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1篇 您的检索式：作者名="C.Yan Cheng"

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		题名	作者	年代	出处	被引量
	1	Human obstructive(postvasectomy)and nonobstructive azoospermia-Insights from scRNA-Seq and transcriptome analysis显示文摘A substantial number of male infertility is caused by azoospermia.However,the underlying etiology and the molecular basis remain largely unknown.Through single-cell(sc)RNA sequencing,we had analyzed testis biopsy samples from two patients with obstructive azoospermia(OA)and nonobstructive azoospermia(NOA).We found only somatic cells in the NOA samples and explored the transcriptional changes in Sertoli cells in response to a loss of interactions with germ cells.Moreover,we observed a germ cell population discrepancy between an OA(postvasectomy)patient and a healthy individual.We confirmed this observation in a secondary study with two datasets at GSM3526588 and GSE124263 for detailed analysis wherein the regulatory mechanisms at the transcriptional level were identified.These findings thus provide valuable information on huma n spermatoge nesis,and we also ide ntified in sightful info rmation for further research on reproducti on-related diseases.	Shitao Chen Geng An Hanshu Wang Xiaolong Wu Ping Ping Longfei Hu Yunmei Chen Jue Fan C.Yan Cheng Fei Sun	2022	Genes & Diseases2022，9，3：	2

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