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| 1 | Stepwise approach and surgery for gallbladder adenomyomatosis: a mini-review显示文摘BACKGROUND: Gallbladder adenomyomatosis (GBA) is a hyperplastic disease affecting the wall of the gallbladder, with some typical features. It has historically been considered a benign condition, nevertheless recent reports highlighted a potential role of GBA in predisposing to malignancies of the gallbladder. DATA SOURCES: We reviewed the literature concerning GBA from its identification until July 2012. Owing to the relative rarity of the disease, studies often are case reports or case series. Thus we herein report a summary of the key-points concerning diagnosis and treatment of GBA, easily applicable in everyday practice, rather than a systematic review. Also, results are integrated with our recent experience. RESULTS: In our experience, we observed a trend toward an increase of GBA during the last years, probably due to enhanced ultrasonographic technical advancements and physician's expertise. GBA has distinctive imaging features. Several recent reports highlight the potential risk of cancer associated with GBA; however the disease is still classified as a benign condition. Although its correlation with malignancy has not been demonstrated, it is prudent to recommend cholecystectomy in some cases. However, in selected asymptomatic patients, a wait-and-see policy is a viable alternative. We propose an algorithm, based on GBA pathological pattern (diffuse, segmental, localized or fundal), suitable for decision-making.CONCLUSIONS: In symptomatic patients and if the diagnosis is doubtful, cholecystectomy is mandatory. Postponing surgery is an option to be offered to asymptomatic patients with low-risk GBA pattern who adhere to scheduled follow-ups. | Gianluca Pellino Guido Sciaudone Giuseppe Candilio Giuseppe Perna Antonio Santoriello Silvestro Canonico Francesco SelvaggiAuthor | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，2： | 9 |
| 2 | Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes显示文摘Fas/CD95 表面受体调停各种各样的房间的快速的死亡打字,包括有为触发 autoimmunity 的潜力的 autoreactive T 房间。这里,我们表明那的船边交货的现在的新奇方面定义一种“社会”的尺寸到导致受体的 apoptosis。船边交货刺激很快导致在附近的 T 房间之间的广泛的膜 nanotube 形成。这极其依赖于 Rho GTPases 然而并非在 caspase 激活上。包括活跃 caspases 的膜和 cytosolic 元素的双向转移能被观察经由这些 nanotubes 发生。Nanotube 形成和死亡信号的细胞间的交换在从有在船边交货受体的自体免疫的 lymphoproliferative 症候群 harbouring 变化的病人的 T 淋巴细胞是有缺点的。我们断定调停 nanotube 的交换组成扩充在附近的 T 房间之间发信号的死亡的繁殖的细胞间的通讯的一种新奇形式。 | Peter D Arkwright Francesca Luchetti Julien Tour Charlotte Roberts Rahna Ayub Ana P Morales Jose J Rodriguez Andrew Gilmore Barbara Canonico Stefano Papa Mauro Degli Esposti | 2010 | Cell Research2010，20，1： | 4 |
| 3 | CD117显示文摘 | Canonico B Felici C Papa S | 2001 | J Biol Regul Homeost Agents2001，15，1： | 2 |
| 4 | Melatonin signaling and cell protection function显示文摘 | Luchetti F Canonico B Betti M | 2010 | FASEB J2010，24，10： | 1 |
| 5 | Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits显示文摘 | Canonico AE Conary JT Meyrick BO | 1994 | Am J Respir Cell Mol Biol1994，10，1： | 1 |
| 6 | Direct brazing of ceramics, graphite and refractory metals显示文摘 | CANONICO D A COLE N C SLAUGHTER G M | 1977 | Welding Journal1977，，8： | 1 |
| 7 | High level of plasma estradiol as a new predictor of ischemic arterial disease in older postmenopausal women:the three-city cohort study显示文摘 | Scarabin-Carre V Canonico M Brailly-Tabard S | | 0，，： | 1 |
| 8 | Melatonin prevents apoptosis induced by UV-B treatment in U937 cell line 显示文摘 | Luchetti F Canonico B Curci R | 2006 | J Pineal Res2006，40，2： | 1 |
| 9 | Progestogens and venous thromboembolism among postmenopausal women using hormone therapy显示文摘 | Canonico M Plu-Bureau G Scarabin PY | 2011 | Maturitas2011，70，4： | 1 |
| 10 | NF-κB mediated regulation of adult hippocampal neurogenesis: relevance to mood disorders and antidepressant activity显示文摘 | Bortolotto V Cuccurazzu B Canonico PL | 2014 | Biomed Res Int2014，2014，61： | 1 |
| 11 | Cerebral manifestations of cefepime toxicity in a dialysis patient显示文摘 | Fishbain JT Monahan TP Canonico MM | 2000 | Neurology2000，55，11： | 1 |
| 12 | Effects of organic tomato pulp powder and nitrite level on the physicochemical, textural and sensory properties of pork luncheon roll 显示文摘 | Hayes J E Canonico I Allen P | 2013 | Meat Science2013，95，3： | 1 |
| 13 | Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits显示文摘 | Canonico AE Conary JT Meyrick BO | 1994 | Am J Respir Cell Mol Biol1994，10，1： | 1 |
| 14 | Lack of in vi-tro interactions using human liver microsomes between ra-beprazole and anticancer drugs显示文摘 | Tamaro I Genazzani A Canonico P | 2009 | Eur J Drug Metab Ph-armacokinet2009，34，1： | 1 |
| 15 | Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: a systematic review and meta-anal- ysis显示文摘 | Canonico M Plu-Bureau G Lowe G DO | 2008 | BMJ2008，336，7665： | 1 |
| 16 | Inguinal hernia repair in parients with human fibrin glue显示文摘 | Canonico S Sciaudione G Pacifico F | 1999 | Surgery1999，125，3： | 1 |
| 17 | Effect of NFE2L2 genetic polymorphism on the association between oral estrogen therapy and the risk of venous thromboembolism in postmenopausal women 显示文摘 | Bouligand J Cabas'et O Canonico M | 2011 | Clin Pharmaeol Ther2011，89，1： | 1 |
| 18 | The association between brain volumes, delirium duration, and cognitive outcomes in intensive care unit survivors: The VISIONS cohort magnetic resonance imaging study*显示文摘 | Max L. Gunther Alessandro Morandi Erin Krauskopf Pratik Pandharipande Timothy D. Girard James C. Jackson Jennifer Thompson Ayumi K. Shintani Sunil Geevarghese Russell R. Miller Angelo Canonico Kristen Merkle Christopher J. Cannistraci Baxter P. Rogers J. | 2012 | Critical Care Medicine2012，，7： | 1 |
| 19 | Progestogen-only contraceptives and the risk of stroke a Meta- analysis显示文摘 | CHAKHTOURA Z CANONICO M GOMPEL A | 2009 | Stroke2009，40，4： | 1 |
| 20 | Effect of NFE2L2 genetic polymor- phism on the association between oral estrogen therapy and the risk of venous thromboembolism in postmenopausal women显示文摘 | Bouligand J Cabaret O Canonico M | 2011 | Clin Pharmacol Ther2011，89，1： | 1 |
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