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您的检索式：作者名="CAO Weixue"
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| 1 | Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripotent stem cells显示文摘Multiple sclerosis(MS) is an autoimmune disease of the central nervous system(CNS), with focal T lymphocytic infiltration and damage of myelin and axons. The underlying mechanism of pathogenesis remains unclear and there are currently no effective treatments. The development of neural stem cell(NSC) transplantation provides a promising strategy to treat neurodegenerative disease. However, the limited availability of NSCs prevents their application in neural disease therapy. In this study, we generated NSCs from induced pluripotent stem cells(iPSCs) and transplanted these cells into mice with experimental autoimmune encephalomyelitis(EAE), a model of MS. The results showed that transplantation of iPSC-derived NSCs dramatically reduced T cell infiltration and ameliorated white matter damage in the treated EAE mice. Correspondingly, the disease symptom score was greatly decreased, and motor ability was dramatically rescued in the iPSC-NSC-treated EAE mice, indicating the effectiveness of using iPSC-NSCs to treat MS. Our study provides pre-clinical evidence to support the feasibility of treating MS by transplantation of iPSC-derived NSCs. | Chao Zhang Jiani Cao Xiaoyan Li Haoyu Xu Weixu Wang Libin Wang Xiaoyang Zhao Wei Li Jianwei Jiao Baoyang Hu Qi Zhou Tongbiao Zhao | 2016 | Science China(Life Sciences)2016，59，9： | 9 |
| 2 | Ultra-thin robust CNT@GC film integrating effective electromagnetic shielding and flexible Joule heating显示文摘The demand for lightweight,thin electromagnetic interference(EMI)shielding film materials with high shielding effectiveness(SE),excellent mechanical properties,and stability in complex environments is particularly pronounced in the realm of flexible and portable electronic products.Here,we developed an ultra-thin film(CNT@GC)in which the glassy carbon(GC)layer wrapped around and welded carbon nanotubes(CNTs)to form a core-shell network structure,leading to exceptional tensile strength(327.2 MPa)and electrical conductivity(2.87×10^(5) S·m^(−1)).The CNT@GC film achieved EMI SE of 60 dB at a thickness of 2µm after post-acid treatment and high specific SE of 3.49×10^(5) dB·cm^(2)·g^(−1),with comprehensive properties surpassing those of the majority of previous shielding materials.Additionally,the CNT@GC film exhibited Joule heating capability,reaching a surface temperature of 135℃at 3 V with a fast thermal response of about 0.5 s,enabling anti-icing/de-icing functionality.This work presented a methodology for constructing a robust CNT@GC film with high EMI shielding performance and exceptional Joule heating capability,demonstrating immense potential in wearable devices,defense,and aerospace applications. | Ding Zhang Chunhui Wang Meng Li Weixue Meng Shipeng Zhang Mengdan Yang Xinguang Huang Yingjiu Zhang Yuanyuan Shang Anyuan Cao | 2024 | Nano Research2024，17，5： | 0 |
| 3 | Distribution Characteristics of Transmitted Diffuse Solar Radiation on the Indoor Surface显示文摘The transparent envelope structure has huge energy-saving potential, which is the key point to reduce building energy consumption and improve the thermal building environment. The solar radiation transmitted through the transparent envelope structure(transmitted solar radiation) is reflected, scattered and absorbed by the indoor surface, which has a significant impact on the heat gain of the building. In this paper, firstly, the diffuse radiation received by different depths of various indoor surfaces is measured by experimental tests, and the distribution function of transmitted diffuse solar radiation(TDSR) on the indoor surface is established. Secondly, the diffuse solar radiation received by the indoor and outdoor surfaces in different seasons is continuously monitored;the variation of TDSR with time is analyzed, and the distribution function of TDSR on indoor surface with time is proposed. Finally, based on the temporal and spatial distribution characteristics of diffuse radiation under different weather conditions, the variation of TDSR with the weather is studied, and the distribution function of TDSR on the indoor surface with weather changes is established. The distribution function of the TDSR on the indoor surface under different depths, time and weather conditions obtained in this study can supplement and improve the theory of building heat gain and load, and help accurate simulation of building energy consumption. | YAO Wanxiang TIAN Wanfeng SHANG Jiacheng HE Haiyan DONG Jiajun CAO Weixue | 2022 | Journal of Thermal Science2022，31，6： | 0 |
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