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| 1 | Cloning of first abc transporter encoding gene from Trichoderma spp. and its expression during stress and mycoparasitism显示文摘Trichoderma in its natural environment competes for nutrient uptake and is required to protect itself from adverse natural toxic compounds, such as those produced by plants and other microbes in the soil community, or synthetic toxic compounds released human activity. One of the most important metabolic pathways for drug resistance and substrate uptake, both in prokaryotes and eukaryotes, is ATP dependent. The role of ABC transporter proteins in the biology of Trichoderma is still not known. We present the cloning of the first four ABC transporter genes (TABC1, TABC2, TABC3, TABC4 ) in Trichoderma, and in particular T. atroviride P1, and the characterization of TABC2 The complete sequence of this gene is 6535 bp, which includes a promoter of 1624 bp, a terminator of 642 bp and a coding region of 4264 bp. The promoter contains many of the potential transcription factor binding sites found in the 5’ upstream region of the ech42 gene of T. atroviride P1. These included: heat shock factors (HSF), a nitrogen-regulating factor (Nit-2), a stress-response element (STRE), a GCR1 elements, and a Cre BP1 motif. Northern analysis and RT-PCR demonstrated that TABC2 is highly expressed when Trichoderma is subjected to nitrogen starvation, grown in the presence of culture filtrates of Botrytis cinerea, Rhizoctonia solani, and Pythium ultimum, or when N-acetylglucosamine is added to the substrate. TABC2 appears to be co-regulated with some CWDE-encoding genes, suggesting that this is the first ABC transporter encoding gene involved in mycoparasitic events. It’s role in the interaction of Trichoderma with fungal hosts or plants is being investigated by targeted gene disruption and overexpression. | Lanzuise S Ruocco M Scala V Catapano L Woo S Ciliento R Ferraioli S Soriente I Vinale F Scala F Del Sorbo G Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 2 |
| 2 | Insight and resistance in patients with obsessive --compulsive disorder 显示文摘 | Catapano F Sperandeo R Perris F | 2001 | Psy- chopathology2001，34，2： | 1 |
| 3 | Treatment of HCV - associated cryoglobulinemic glomerulonephritis 显示文摘 | Laurino S Borrelli S Catapano F | 2009 | G Ital Nefrol2009，26，3： | 1 |
| 4 | Long pentraxin 3:experimental and clinical relevance in cardiovascular disease 显示文摘 | Bonacina F Baragetti A Catapano AL | 2012 | Mediators inflamm2012，23，2： | 1 |
| 5 | Insight and resistance in patients with obsessive-compulsive disorder显示文摘 | Sperandeo R Perris F | 2001 | Psychopathology2001，34，： | 1 |
| 6 | The anti-proliferative effect of synthetic peptidyl GH secretagogues in human CALU-1 lung carcinoma cells显示文摘 | Ghe C Cassoni P Catapano F | 2002 | Endocrinology2002，143，： | 1 |
| 7 | In human endothelial cells amino acids inhibit insulin-induced Akt and ERK1/2 phosphorylatlon by an roTOR-dependent mechanism 显示文摘 | PELLEGATrA F CATAPANO A L LUZI L | 2006 | J Cardiovase Pharmacol2006，47，5： | 1 |
| 8 | Obses- sive-compulsive disorder with poor insight: a three year pro- spective study显示文摘 | CATAPANO F PERRIS F FABRAZZO M | 2010 | Prog Neuropsychopharmacol Biol Psychia- try2010，，： | 1 |
| 9 | Plasma exchange for re- nal vasculitis and idiopathic rapidly progressive glomerulone- phritis : a meta-analysis 显示文摘 | Walsh M Catapano F Szpirt W | 2010 | Am J Kidney Dis2010，57，： | 1 |
| 10 | MicroRNAs and lipopro- teins: a connection beyond atherosclerosis? 显示文摘 | Norata GD Sala F Catapano AL | 2013 | Atherosclerosis2013，227，2： | 1 |
| 11 | Plasma exchange for renal vasculitis and idiopathic rapidly progressive glomerulonephritis: a meta- analysis显示文摘 | Walsh M Catapano F Szpirt W | 2011 | Am J Kidney Dis2011，57，4： | 1 |
| 12 | Long pentraxin 3:experimental and clinical relevance in cardiovascular diseases 显示文摘 | Bonacina F Baragetti A Catapano AL | 2013 | Mediators Inflamm2013，2013，72： | 1 |
| 13 | Decreased blood levels of tumor necrosis fctor-alpha patients with obsessive-complusive disorder显示文摘 | Monteleone P Catapano F Fabrazzo M | | 0，，4： | 1 |
| 14 | Plasma ex- change for renal vasculitis and idiopathic rapidly progressive glomerulonephritis: a meta- analysis 显示文摘 | Walsh M Catapano F Szpirt W | 2011 | Am J Kidney Dis2011，57，： | 1 |
| 15 | Dexamethasone suppression test in patients with primary obsessive-compulsive disorder and in healthy controls显示文摘 | Catapano F Monteleone P Maj M | 1990 | Neuropsychobiology1990，23，2： | 1 |
| 16 | Pharmacology of competitive inhibitors of HMG-CoA reductase 显示文摘 | Corsini A Maggi F M Catapano A L | 1995 | Pharmacol Res1995，31，： | 1 |
| 17 | The anti-proliferative effect of synthetic peptidyl GH secretagogues in human CALU-1 lung carcinoma cells显示文摘 | Ghe C Cassoni P Catapano F | 2002 | Endocrinology2002，143，： | 1 |
| 18 | Effects of calcium antagonists on lipids and atherosclerosis显示文摘 | Catapano AL Corsini A et ai | 1989 | Am J Cardiol1989，64，： | 1 |
| 19 | Rosuvastatin: pharmacologic features 显示文摘 | Bemini F Catapano AL | 2003 | Ital Heart J2003，47，： | 1 |
| 20 | Thermodynamic and optical characterizations of a high performance GDI engine operating in homogeneous and stratified chargemixture conditions fueled with gasoline and bio-ethanol 显示文摘 | Sementa P Vaglieco B M Catapano F | 2012 | Fuel2012，96，： | 1 |
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