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| 1 | Senescence and p130/Rb12: a new beginning to the end显示文摘 | Francesco P Fiorentinot Catherine E Symonds Marcella Macaluso Antonio Giordano | 2009 | Cell Research2009，19，9： | 3 |
| 2 | Metabolite profile comparisons between ascending and descending colon tissue in healthy adults显示文摘BACKGROUND Obesity is a risk factor for colorectal cancer,yet metabolic distinctions between healthy right and left colon tissue,before cancer is diagnosed,remains largely unknown.This study compared right-ascending and left-descending colon tissue metabolomes to identify differences from the stool metabolome in normal weight,overweight,and obese adults.AIM To examine right and left colon tissue metabolites according to body mass index that may serve as mechanistic targets for interventions and biomarkers for colon cancer risk.METHODS Global,non-targeted metabolomics was applied to assess right-ascending and left-descending colon tissue collected from healthy adults undergoing screening colonoscopies to test the hypothesis that BMI differentially impacts colon tissue metabolite profiles.The colon tissue and stool metabolome of healthy adults(n=24)was analyzed for metabolite signatures and metabolic pathway networks implicated in progression of colorectal cancer.RESULTS Ascending and descending colon contained 504 host,food,and microbiotaderived metabolites from normal weight,overweight and obese adults grouped according to body mass index.Amino acids,lipids,and nucleotides were among the chemical types that further differentiated from the stool metabolite profiles.Normal weight adults had 46 significantly different metabolites between ascending and descending colon tissue locations,whereas there were 37 metabolite differences in overweight and 28 metabolite differences for obese adults(P<0.05).Obese adults had trimethylamine N-oxide,endocannabinoids and monoacylglycerols with different relative abundances identified between ascending and descending colon.Primary and secondary bile acids,vitamins,and fatty acids also showed marked relative abundance differences in colon tissue from overweight/obese adults.CONCLUSION There were metabolite profile differences between right-ascending and leftdescending colon tissue in healthy adults.Colon lipids and other metabolites in obese and overweight adults were distinguished from normal weight participants and associated with gut inflammation,nutrient absorption,and products of microbiota metabolism. | Bridget A Baxter Kristopher D Parker Michael J Nosler Sangeeta Rao Rebecca Craig Catherine Seiler Elizabeth P Ryan | 2020 | World Journal of Gastroenterology2020，26，3： | 2 |
| 3 | Rheological behavior of water-in-oil emulsions stabilized by hydrophobic bentonite particles显示文摘 | Bernard P Binks John H Chnt Catherine P Whitby | 2005 | Langmuir2005，21，21： | 1 |
| 4 | Directions for productivity measurement in fisheries显示文摘 | Felthovena R G Catherine J Morrison P | 2004 | Marine Policy2004，28，： | 1 |
| 5 | CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients显示文摘 | Savoldo Barbara Ramos Carlos Almeida Liu Enli Mims Martha P Keating Michael J Carrum George Kamble Rammurti T Bollard Catherine M Gee Adrian P Mei Zhuyong Liu Hao Grilley Bambi Rooney Cliona M Heslop Helen E Brenner Malcolm K Dotti Gianpie | 2011 | Journal of Clinical Investigation2011，，5： | 1 |
| 6 | The Delphi technique: myths and realities显示文摘 | Catherine P | 2003 | J ofAdv Nurs2003，414，： | 1 |
| 7 | Human Bcl-2 protects against AMPA receptor-mediated apoptosis 显示文摘 | Nam S C Philip M B Catherine J P | 2000 | Neurochem2000，74，4： | 1 |
| 8 | FromGreta's mind to her face:modelling the dynamics of affectivestates in a conversational embodied Agent显示文摘 | FIORELLA DE R CATHERINE P POGGI I | 2003 | InternationalJournal of Human-Agent Studies2003，59，12： | 1 |
| 9 | Agglomeration econo- mies and industry location decisions:the impacts of spatial and in- dustrial spiUovers 显示文摘 | Jeffrey P Cohen Catherine J Morrison Paul | 2005 | Regional Science and Urban Economics2005，，35： | 1 |
| 10 | Electrical Characteristics and Growth Kinetics in Discharges Used for Plasma Deposition of Amorphous Carbon显示文摘 | Catherine Y Couderc P | 1986 | Thin Solid Films1986，144，2： | 1 |
| 11 | Automation and optimization of glycine Synthesis显示文摘 | Mehrdad N Catherine P | 1996 | Process Control Qual1996，8，1： | 1 |
| 12 | Remote sensing of global wetland dynamics with multiple satellite data sets显示文摘 | Catherine P Elaine M Filipe A | 2001 | Geophysical Researeh Letters2001，28，15： | 1 |
| 13 | Docetaxel and Estramustine Compared with Mitoxantrone and Prednisone for Advanced Refractory Prostate Cancer显示文摘 | Daniel P Petrylak M D Catherine M | 2004 | N Engl J Med2004，351，： | 1 |
| 14 | Forces on adhesive contacts a ffect cell function显示文摘 | Catherine G Galbraith Michael P Sheetz | 1998 | Cell Biology1998，10，： | 1 |
| 15 | Differentiation of vascular tumorsfrom vascular malformations by expression of Wilms tumor 1 gene: Eval-uation of 126 cases显示文摘 | Rola AD Julie P Catherine M | 2010 | J AM ACAD DERMATOL2010，63，6： | 1 |
| 16 | A recombinant fowl adenovirus expressing the S1 gene of infectious bronchitis virus protects against challenge with infectious bronchitis virus 显示文摘 | Michael A Catherine P Jagoda I | 2003 | Vaccine2003，21，： | 1 |
| 17 | Socioeconomic status in health research: title and subtitle break one size doos not fit all显示文摘 | Paula A Braveman M M Catherine Cubbiu P Susan Ege-ler P et at | 2005 | jama-Journal of the American Medical Association2005，294，22： | 1 |
| 18 | Evaluating the Environmental Impact of Products and Production Processes:A Comparison of Six Methods 显示文摘 | Edgar G H William S P Catherine P K | 1997 | The Science of the Total Environment1997，196，1： | 1 |
| 19 | Effects of secondary phases on the damping behavior of metal,alloys and metal matrix composites显示文摘 | Zhang Jinmin Robert J P Catherine R W | | 0，，08： | 1 |
| 20 | Pro-gress in developing cationic vectors for nonviral systemicgene therapy against cancer 显示文摘 | MARIE M CATHERINE P ARNAUD V | 2008 | Biomaterials2008，29，： | 1 |
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