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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Mercury speciation in fluorescent lamps by thermal release analysis显示文摘 | CLAUDIO R CLAUDIO C WALTER A D J | 2003 | Waste Management2003，23，10： | 1 |
| 3 | Combined biological and chemical degradation for treating a mature municipal landfill leachate 显示文摘 | Claudio D I Roberti R Lopez A | 2006 | Biochemical Engineering Journal2006，31，7： | 1 |
| 4 | Multibaseline In SAR DEM Reconstruction:the Wavelet Approach显示文摘 | FERRETTI A CLAUDIO P FABIO R | 1999 | IEEE Transactions on Geoscience and Remote Sensing1999，37，2： | 1 |
| 5 | Crystallization of the a and y forms of Isotactic Polypropylene as a Tool to Test the Degree of Segregation of Defects in the Polymer Chains显示文摘 | Claudio D R Finizia A Teresa C | 2002 | Macromolecules2002，35，9： | 1 |
| 6 | Obtaining CeO2-ZrO2 mixed oxides by coprecipitation:role of preparation conditions显示文摘 | Sonia L Claudio A T Roberto R A | 2005 | Applied Catalysis B:Environmental2005，58，34： | 1 |
| 7 | Combined biological and chemicaldegradation for treating a mature municipal landfill leachate 显示文摘 | Claudio D I Roberti R Lopez A | 2006 | Biochemical Engineering Journal2006，31，7： | 1 |
| 8 | Protein purification from polyacrylamide gels by sonication extraction显示文摘 | CLAUDIO A R PAULA T ELIAS W A | 1999 | Anal Biochem1999，268，： | 1 |
| 9 | Electrokinetic-enhanced phytoremediation of soils:Status and opportunities显示文摘 | Claudio Cameselle Chirakkara Reshma A Reddy Krishna R | 2013 | Chemosphere2013，93，4： | 1 |
| 10 | Magnetic resonance and echocardiography imaging of pulmonary artery size throughout stages of Fontan reconstruction显示文摘 | Mark A Mary T Claudio R | 1994 | Circulation1994，90，6： | 1 |
| 11 | Anatomical and func- tional results of macular hole retinal detachment surgery in patients with high myopia and posterior staphyloma treated with perfluoropropane gas or silicone oil显示文摘 | MANCINO R CIUFFOLETTI E MARTUCCI A ALESSIO M FRANCESCO A CLAUDIO C | 2013 | Retina2013，33，3： | 1 |
| 12 | Cardiaorenal syndrome显示文摘 | CLAUDIO R MIKKO H ANDREW A | 2008 | J Am Coll Cardiol2008，52，： | 1 |
| 13 | Cationic rhodium (Ⅰ) complexes containing 4, 4'-disubstituted 2,2'-bipyridines: A systematic variation on electron density over the metal centre 显示文摘 | Paulo E A R Claudio L D | 2006 | J Organomet Chem2006，691，： | 1 |
| 14 | Characterization of powder metallurgy (PM) nickel base superalloys for aeronautical applications 显示文摘 | Silva J M Claudio R A Sousae Brito A | 2006 | Materials Science Forum2006，514，516： | 1 |
| 15 | Preoperative serum levels of CA 72-4,CEA,CA 19-9,and alpha-fetoprotein in patients with gastric cancer显示文摘 | REJANE M CLAUDIO R A GIOVANNI M D | 2002 | Rev Hosp Clin Fac Med S Paulo2002，57，3： | 1 |
| 16 | Performance of modified montmorillonite clay in mercury adsorption process and thermodynamic studies显示文摘 | Denis L G Claudio A Rubia R V | 2008 | Inorganic Chemistry Communications2008，11，1： | 1 |
| 17 | Adsorption of mercury cation on chemically modified clay显示文摘 | Denis L G Rubia R V Claudio A | 2009 | Materials Research Bulletin2009，44，3： | 1 |
| 18 | Glycerol acetals as anti- freezing additives for biodiesel显示文摘 | Paulo H R Valter L C Claudio J A | 2010 | Bioresource technology2010，101，15： | 1 |
| 19 | Obtaining CeO2-ZrO2 mixed oxides by coprecipitation:role of preparation conditions显示文摘 | Sonia L Claudio A T Roberto R A | 2005 | Applied Catalysis B:Environmental2005，58，20： | 1 |
| 20 | A1N/Diamond np-junctions 显示文摘 | Christoph E Nebel Claudio R Miskys Jose A Garrido | 2003 | Diamond & Related Materials2003，12，： | 1 |
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