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| 1 | Characterization of functional biliary pain and dyspeptic symptoms in patients with sphincter of Oddi dysfunction:Effect of papillotomy显示文摘AIM: To characterize functional biliary pain and other gastrointestinal (GI) symptoms in postcholecystectomy syndrome (PCS) patients with and without sphincter of Oddi dysfunction (SOD) proved by endoscopic sphincter of Oddi manometry (ESOM), and to assess the post- endoscopic sphincterotomy (EST) outcome. METHODS: We prospectively investigated 85 cholecystectomized patients referred for ERCP because of PCS and suspected SOD. On admission, all patients completed our questionnaire. Physical examination, laboratory tests, abdominal ultrasound, quantitative hepatobiliary scintigraphy (QHBS), and ERCP were performed in all patients. Based on clinical and ERCP findings 15 patients had unexpected bile duct stone disease and 15 patients had SOD biliary typeⅠ. ESOM demonstrated an elevated basal pressure in 25 patients with SOD biliary-type Ⅲ. In the remaining 30 cholecystectomized patients without SOD, the liver function tests, ERCP, QHBS and ESOM were all normal. As a control group, 30 ‘asymptomatic’ cholecystectomized volunteers (attended to our hospital for general cardiovascular screening) completed our questionnaire, which is consisted of 50 separate questions on GI symptoms and abdominal pain characteristics. Severity of the abdominal pain (frequency and intensity) was assessed with a visual analogue scale (VAS). In 40 of 80 patients having definite SOD (i.e. patients with SOD biliary typeⅠand those with elevated SO basal pressure on ESOM), an EST was performed just after ERCP. In these patients repeated questionnaires were filled at each follow-up visit (at 3 and 6 mo) and a second lookQHBS was performed 3 mo after the EST to assess the functional response to EST. RESULTS: The analysis of characteristics of the abdominal pain demonstrated that patients with common bile duct stone and definite SOD had a significantly higher score of symptomatic agreement with previously determined biliary-like pain features than patient groups of PCS without SOD and controls. In contrary, no significant differences were found when the pain severity scores were compared in different groups of PCS patients. In patients with definite SOD, EST induced a significant acceleration of the transpapillary bile flow; and based on the comparison of VASs obtained from the pre- and post-EST questionnaires, the severity scores of abdominal pain were significantly improved, however, only 15 of 35 (43%) patients became completely pain free. Post-EST severity of abdominal pain by VASs was significantly higher in patients with predominant dyspepsia at initial presentation as compared to those without dyspeptic symptoms. CONCLUSION: Persistent GI symptoms and general patient dissatisfaction is a rather common finding after EST in patients with SOD, and correlated with the presence of predominant dyspeptic symptoms at the initial presentation, but does not depend on the technical and functional success of EST. | László Madácsy Roland Fejes Gábor Kurucsai Ildikó Joó András Székely Viktória Bertalan Attila Szepes János Lonovics | 2006 | World Journal of Gastroenterology2006，12，42： | 33 |
| 2 | Endoscopic transluminal pancreatic necrosectomy using a self-expanding metal stent and high-flow water-jet system显示文摘Walled-off pancreatic necrosis and a pancreatic abscess are the most severe complications of acute pancreatitis. Surgery in such critically ill patients is often associated with significant morbidity and mortality within the first few weeks after the onset of symptoms. Minimal invasive approaches with high success and low mortality rates are therefore of considerable interest. Endoscopic therapy has the potential to offer safe and effective alternative treatment. We report here on 3 consecutive patients with infected walled-off pancreatic necrosis and 1 patient with a pancreatic abscess who underwent direct endoscopic necrosectomy 19-21 d after the onset of acute pancreatitis. The infected pancreatic necrosis or abscess was punctured transluminally with a cystostome and, after balloon dilatation, a non-covered self-expanding biliary metal stent was placed into the necrotic cavity. Following stent deployment, a nasobiliary pigtail catheter was placed into the cavity to ensure continuous irrigation. After 5-7 d, the metal stent was removed endoscopically and the necrotic cavity was entered with a therapeutic gastroscope. Endoscopic debridement was performed via the simultaneous application of a high-flow water-jet system; using a flush knife, a Dormia basket, and hot biopsy forceps. The transluminal endotherapy was repeated 2-5 times daily during the next 10 d. Supportive care included parenteral antibiotics and jejunal feeding. All patients improved dramatically and with resolution of their septic conditions; 3 patients were completely cured without any further complications or the need for surgery. One patient died from a complication of prolonged ventilation severe bilateral pneumonia, not related to the endoscopic procedure. No procedure related complications were observed. Transluminal endoscopic necrosectomy with temporary application of a self-expanding metal stent and a high-flow water-jet system shows promise for enhancing the potential of this endoscopic approach in patients with walled-off pancreatic necrosis and/or a pancreatic abscess. | István Hritz Roland Fejes András Székely Iván Székely László Horváth gnes Sárkány ron Altorjay László Madácsy | 2013 | World Journal of Gastroenterology2013，19，23： | 10 |
| 3 | Evaluation of the biliary tract in patients with functional biliary symptoms显示文摘这篇论文的目的是在这些病人为胆道的评估描述功能的胆汁的症候群和方法。没有可论证的器官的底层,功能的胆汁的症状能被定义为胆汁的症状。二主要症候群存在:胆囊机能障碍和 Oddi 机能障碍的括约肌。最重要的研究工具是 cholescintigraphy 和 Oddi 测压法的内视镜的括约肌。在胆囊机能障碍 scintigraphic 胆囊喷射部分在下面 35% 能选择将得益于胆囊炎的病人。Oddi 测压法的内视镜的括约肌在 Oddi 机能障碍的括约肌被认为标准答案,但是在 scintigraphic 方法的最近的开发就要改变这。因此, hilum-to-duodenum 运输时间的计算和 cholescintigraphy 上的十二指肠的外观时间在这些病人证明了有用。在结论,周围的方法能诊断功能的胆汁的症候群。然而,仍然有很多个问题,知识进一步被需要。可能,下一个向前走将在感觉测试和阻抗 planimetric 方法的区域。 | Peter Funch-Jensen Asbjφrn Mohr Drewes László Madácsy | 2006 | World Journal of Gastroenterology2006，12，18： | 6 |
| 4 | Study of humic-like substances in fog and interstitial aerosol by size-exclusion chromatography and capillary electrophoresis显示文摘 | Z Krivácsy Gy Kiss B Varga I Galambos Zs Sárvári A Gelencsér á Molnár S Fuzzi M.C Facchini S Zappoli A Andracchio T Alsberg H.C Hansson L Persson | 2000 | Atmospheric Environment2000，，25： | 1 |
| 5 | Prophylactic pancreas stenting followed by needle-knife fistulotomy in patients with sphincter of Oddi dysfunction and difficult cannulation:new method to prevent post-ERCP pancreatitis显示文摘 | MADáCSY L KURUCSAI G FEJES R | 2009 | Dig Endosc2009，21，1： | 1 |
| 6 | Aldose reductase inhibi- tion suppresses oxidative stress-induced inflammatory disorders 显示文摘 | Satish KS Umesh CSY Aramati BMR | 2011 | Chem Biol Interact2011，191，13： | 1 |
| 7 | Importance of organic and blackcarbon in atmospheric aerosols at Mace Head,on the West Coast of Ireland (531190N,91540W)显示文摘 | Kleefeld S Hoffer A Krivácsy Z | 2002 | Atmospheric Environment2002，36，： | 1 |
| 8 | Video manometry of the sphincter of Oddi:a new aid for interpreting manometric tracings and excluding manometric artefacts显示文摘 | Madácsy L Middelfart HV Matzen P | 2000 | Endoscopy2000，32，1： | 1 |
| 9 | Changes in mesopic vision after photorefractive keratectomy for myopia显示文摘 | Nagy ZZ Munkácsy G Krueger RR | 2002 | J Refract Surg2002，18，3： | 1 |
| 10 | Study of water-soluble atmospheric humic matter in urban and marine environments显示文摘 | Zoltán Krivácsy Gyula Kiss Darius Ceburnis Gerard Jennings Willy Maenhaut Imre Salma David Shooter | 2007 | Atmospheric Research2007，，1： | 1 |
| 11 | Gallbladder hypomotility in diabetic polyneuropathy显示文摘 | Tamás T. Várkonyi M.D. Csaba Lengyel M.D. László Madácsy M.D. Borbála Vel?sy M.D. Ph.D. Péter Kempler M.D. Ph.D. D.Sc. Tamás Fazekas M.D. Ph.D. D.Sc. László Pávics M.D. Ph.D. László Csernay M.D. Ph.D. D.Sc. János Lonovics M.D. Ph.D | 2001 | Clinical Autonomic Research2001，，6： | 1 |
| 12 | Effect of a protective ventilation strategy on mortality in the acute respiratory distress syndrome 显示文摘 | AMATO MBP BARBAS CSY MEDIROD DM | 1998 | New Engl J Med1998，338，： | 1 |
| 13 | Recombinant human growth hormone显示文摘 | Trios NA Mantzoros CSY | | 0，，： | 1 |
| 14 | A 2-year longitudinal study of myopia progression and optical component changes among Hong Kong schoolchildren显示文摘 | Lam CSY Edwards M Millodot M | | 0，，06： | 1 |
| 15 | Assessment of nerve excitability in toxic and metabolic neuropathies显示文摘 | Krishnan AV Lin CSY Park SB | 2008 | Journal of the Peripheral Nervours System2008，，： | 1 |
| 16 | Prophylactic pan-creas stenting followed by needle - knife fistulotomy in patients withsphincter of oddi dysfunction and difficult cannulation: new methodto prevent post - ERCP pancreatitis显示文摘 | MADCSY L KURUCSAI G FEJES R | 2009 | Dig Endosc2009，21，21： | 1 |
| 17 | Parallel corpora for medium density languages显示文摘 | Varga D Halácsy P Kornai A | 2007 | AMSTERDAM STUDIES IN THE THEORY AND HISTORY OF LINGUISTIC SCIENCE SERIES 42007，292，： | 1 |
| 18 | PPAR-γ2 Pro12Ala polymorphism is associated with post-challenge abnormalities of glucose homeostasis in children and adolescents with obesity显示文摘 | Agnes Jermendy Anna K?rner Margit Kovács László Madácsy Károly Cseh | 2011 | Journal of Pediatric Endocrinology and Metabolism (-)2011，，1： | 1 |
| 19 | Importance of organic and black carbon in atmospheric aerosols at Mace Head, on the West Coast of Ireland (53°19′N, 9°54′W)显示文摘 | S Kleefeld A Hoffer Z Krivácsy S.G Jennings | 2002 | Atmospheric Environment2002，，28： | 1 |
| 20 | Nerve excitability changes in critical illness polyneuropathy显示文摘 | Graggen WJZ Lin CSY Howard RS | 2006 | Brain2006，129，： | 1 |
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