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| 1 | Diabetic neuropathic pain:Physiopathology and treatment显示文摘Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes,which affects over 90% of the diabetic patients.Although pain is one of the main symptoms of diabetic neuropathy,its pathophysiological mechanisms are not yet fully known.It is widely accepted that the toxic effects of hyperglycemia play an important role in the development of this complication,but several other hypotheses have been postulated.The management of diabetic neuropathic pain consists basically in excluding other causes of painful peripheral neuropathy,improving glycemic control as a prophylactic therapy and using medications to alleviate pain.First line drugs for pain relief include anticonvulsants,such as pregabalin and gabapentin and antidepressants,especial y those that act to inhibit the reuptake of serotonin and noradrenaline.In addition,there is experimental and clinical evidence that opioids can be helpful in pain control,mainly if associated with first line drugs.Other agents,including for topical application,such as capsaicin cream and lidocaine patches,have also been proposed to be useful as adjuvants in the control of diabetic neuropathic pain,but the clinical evidence is insufficient to support their use.In conclusion,a better understanding of the mechanisms underlying diabetic neuropathic pain will contribute to the search of new therapies,but also to the improvement of the guidelines to optimize pain control with the drugs currently available. | Anne K Schreiber Carina FM Nones Renata C Reis Juliana G Chichorro Joice M Cunha | 2015 | World Journal of Diabetes2015，6，3： | 34 |
| 2 | Feeding behaviour of fast- and slow-growing stains of rainbow trout,Oncorhynchus mykiss (Walbaum) during first feeding 显示文摘 | Valente L M P Saglio P Cunha L M | 2001 | Aquaculture Research2001，32，： | 1 |
| 3 | The nonsubsampled Contourlet transform: theory, design, and applications 显示文摘 | Cunha A L Zhou J Do M N | 2006 | IEEE Transactions on Image Process2006，15，10： | 1 |
| 4 | Multiloop edgewise archwire in the treatment of a patient with an anterior open bite and a long face显示文摘 | Ribeiro GL Regis S Jr da Cunha Tde M | 2010 | Am J Orthod Dentofacial Orthop2010，138，1： | 1 |
| 5 | Postobturation pain and associated factors in adolescent patients undergoing one-and two-visit root canal treatment显示文摘 | Risso P Cunha A Araujo M | 2008 | Journal of Den- tistry2008，36，11： | 1 |
| 6 | The electronic properties of sputtered chromium and iron oxide films显示文摘 | G Goodlet S Faty S Cardoso P.P Freitas A.M.P Sim?es M.G.S Ferreira M Da Cunha Belo | 2003 | Corrosion Science2003，，6： | 1 |
| 7 | Characterization of Pore Systems in Seal Rocks Using Nitrogen Gas Adsorption Combined with Mercury Injection Capillary Pressure Techniques 显示文摘 | Schmitt M Fernandes C P da Cunha Neto J A B | 2013 | Marine and Petroleum Geology2013，39，1： | 1 |
| 8 | Widely used herpes simplex virus 1 ICP0 deletion mutant strain d11403 and its derivative viruses do not express glycoprotein C due to a secondary mutation in the gC gene显示文摘 | Cunha C W Taylor K E Pritchard S M | 2015 | Plos One2015，10，13： | 1 |
| 9 | PAHs in SD: polycyclic aromatic hydrocarbons levels in street dust in the central area of Niter6i City, R J, Brazil显示文摘 | NettoA D P Krauss T M Cunha I F | 2006 | Water Air and Soll Pollution2006，176，14： | 1 |
| 10 | Larviculture of marine fish: problems and perspectives显示文摘 | | 1999 | Aquaculture1999，177，： | 1 |
| 11 | Sequential solid-state and submerged cultivation of Aspergillus niger on sugarcane bagasse for the production of cellulose显示文摘 | Cunha F M Esperanca M N Zangirolami T C | 2012 | Bioresource Technology2012，112，： | 1 |
| 12 | Toxoplasma gondii: humoral and cellular immune response of BALB/c mice immu- nized via intranasal route with rTgROP2 显示文摘 | Igarashi M Zulpo DL Cunha IA | 2010 | Rev Bras Parasitol Vet2010，19，4： | 1 |
| 13 | Effect of milk fatand total solids concentration on the kinetics of moistureuptake by ready-to-eat breakfast cereal 显示文摘 | Machado M F Oliveira FAR Cunha L M | 1999 | InternationalJournal of Food Science and Technology1999，34，1： | 1 |
| 14 | The NonSubsampled Contourlet Transform: Theory, design, and applications 显示文摘 | Cunha A L Zhou J and Do M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 15 | The nonsub-sampled contourlet transform:theory,design and applica-tions显示文摘 | Da Cunha A L Zhou Jiangping Do M N | 2006 | IEEE Trans on Image Proecess2006，15，10： | 1 |
| 16 | A Voltammetric Study of the Electrodeposition of CuInSe2 in a Citrate Electrolyte显示文摘 | Oliveira M Azevedo M Cunha A | 2002 | Thin Solid Films2002，405，： | 1 |
| 17 | The nonsubsampledcontourlet transform : theory,design,and applica-tions 显示文摘 | Cunha A L Zhou J Do M N | 2006 | IEEE Transactions on Image Process-ing2006，15，10： | 1 |
| 18 | Removal of aromatics from multi-component organic mixtures bypervaporation using polyurethane membranes: experimenttal and modeling显示文摘 | Cunha V S Paredes M L L Nobrega R | 2002 | J Membr Sci2002，206，： | 1 |
| 19 | Measuring self- efficacy to deal with infertility: psychometric properties and confirmatory factor analysis of the Portuguese ver- sion of the infertility self-efficacy scale显示文摘 | Galhardo A Cunha M Pinto-Gouveia J | 2013 | Res Nurs Health2013，36，1： | 1 |
| 20 | The effect of the glucono-8-1actone/caseinate ratio on sodium caseinate gelation显示文摘 | BRAGA A L M MENOSSI M CUNHA R L | 2006 | International Dairy Journal2006，16，5： | 1 |
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