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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Effect of air-oxygen and argon-oxygen mixtures on dielectric barrier dischargedecomposition of toluene显示文摘 | Cabrera O G Callejas R L Valencia R | 2004 | Brazilian Journal of Physics2004，34，4： | 1 |
| 3 | Genetic Polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) Genes Associated With Pathological Characteristics of Prostate Cancer in the Ecuadorian Population显示文摘 | Andrés López-Cortés Gabriela Jaramillo-Koupermann María J. Mu?oz Alejandro Cabrera Carolina Echeverría Felipe Rosales Nicolás Vivar César Paz-y-Mi?o | 2013 | The American Journal of the Medical Sciences2013，，： | 1 |
| 4 | Highstrength concrete with different fine aggregate显示文摘 | DONZA H CABRERA O IRASSAR E F | 2002 | Cement and Concrete Research2002，32，11： | 1 |
| 5 | High-strength concrete with different fine aggregate显示文摘 | H Donza O Cabrera E.F Irassar | 2002 | Cement and Concrete Research2002，，11： | 1 |
| 6 | The mitechondrial genome of Moniliophthora roreri,the frosty pod rot pathogen of cacao显示文摘 | COSTA G G L CABRERA O G TIBURCIO R A | 2012 | Fungal biology2012，116，5： | 1 |
| 7 | 17β-estradiol and testos- terone in soil and runoff from grasslands amended with broiler litter显示文摘 | Finlay-Moore O Hartel P G Cabrera M L | 2000 | Journal of Environmental Quality2000，29，5： | 1 |
| 8 | Lithium protects against glucocorticoid induced neural progenitor cell ap- optosis in the developing cerebellum显示文摘 | Cabrera O Dougherty J Singh S | 2014 | Brain Res2014，1545，： | 1 |
| 9 | Photocatalytic reactions involving hydroxyl radical attack显示文摘 | Alfano O M Cabrera M I Cassano A E | 1997 | J Catal1997，172，： | 1 |
| 10 | Wunderlich syndrome as mani-festation of leiomyosarecoma of the kidney显示文摘 | Ortiz O Gonz'a|ez Cabrera L A Arap A | 1990 | Arch Esp Urol1990，43，： | 1 |
| 11 | Protein and lysine digestibility and protein quality of cooked Filipino rice diets and milled rice in growing rats显示文摘 | EGGUM B O CABRERA M I Z | 1993 | Plant Foods for Human Nutrition1993，43，2： | 1 |
| 12 | 17β-estradiol and testosterone in Soil and runoff from grasslands amended with broiler litter显示文摘 | FINLAY-MOORE O HARTEL P G CABRERA M L | 2000 | J Environ Qual2000，29，： | 1 |
| 13 | Protein and lysine digestibility and protein quality of cooked Filipino rice diets and milled rice in growing rats显示文摘 | EGGUM B O CABRERA M I JULIANO B O | 1993 | Plant Foods for Human Nutrition1993，43，2： | 1 |
| 14 | Novel reactor for photocatalytic kinetic studies显示文摘 | CABRERA M I ALFANO O M CASSANO A E | 1994 | Ind Eng Chem Res1994，33，12： | 1 |
| 15 | Structure–activity relationship of mastoparan analogs: Effects of the number and positioning of Lys residues on secondary structure, interaction with membrane-mimetic systems and biological activity显示文摘 | Bibiana Monson de Souza Marcia Perez dos Santos Cabrera Paulo Cesar Gomes Nathalia Baptista Dias Rodrigo Guerino Stabeli Natalia Bueno Leite Jo?o Ruggiero Neto Mario Sergio Palma | 2015 | Peptides2015，，： | 1 |
| 16 | Non-isothermal stamp forming of continuous tape reinforced all-polypropylene composite sheet 显示文摘 | CABRERA N O REYNOLDS C T ALCOCK B | 2008 | Composites Part A2008，39，： | 1 |
| 17 | Wavelet neural networks are asymptotically optimal approximators for {unctions of one variable显示文摘 | Kreinovieh V Sirisaengtaksin O Cabrera S | 1994 | Neural Networks1994，，1： | 1 |
| 18 | Noninvasive in vivo imaging of pancreatic islet cell biology显示文摘 | Speier S Nyqvist D Cabrera O | | 0，，： | 1 |
| 19 | Endogenously released ATP serves as a positive autocrine feedback loop for the human pancreatic beta cell显示文摘 | Jacques-Silva M Cabrera O Makeeva N | 2008 | Purinergic Signal2008，4，： | 1 |
| 20 | Intravenous thrombolysis with recombinant tissue plasminogen activator in vascular warning syndromes显示文摘 | Gonzglez Herngndez A Fabre Pi O Cabrera Naranjo F | 2014 | Neurologia2014，29，： | 1 |
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