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| 1 | Bouveret's syndrome complicated by a distal gallstone ileus显示文摘AIM: Gastric outlet obstruction caused by duodenal impaction of a large gallstone migrated through a cholecystoduodenal fistula has been referred as Bouveret's syndrome. Endoscopic lithotomy is the first-step treatment,however, surgery is indicated in case of failure or complication during this procedure.METHODS: We report herein an 84-year-old woman presenting with features of gastric outlet obstruction due to impacted gallstone. She underwent an endoscopic retrieval which was unsuccessful and was further complicated by distal gallstone ileus. Physical examination was irrelevant.RESULTS: Endoscopy revealed multiple erosions around the cardia, a large stone in the second part of the duodenum causing complete obstruction, and wide ulceration in the duodenal wall where the stone was impacted. Several attempts of endoscopic extraction by using foreign body forceps failed and surgical intervention was mandatory. Preoperative ultrasound evidenced pneumobilia whilst computerized tomography showed a large stone, 5 cm×4 cm×3 cm, loggingat the proximal jejunum and another one, 2.5 cm×2 cm×2 cm,in the duodenal bulb causing a closed-loop syndrome. She underwent laparotomy and the jejunal stone was removed by enterotomy. Another stone reported as located in the duodenum preoperatively was found to be present in the gallbladder by intraoperative ultrasound. Therefore,cholecystoduodenal fistula was broken down, the stone was retrieved and cholecystectomy with duodenal repair was carried out. She was discharged after an uneventful postoperative course.CONCLUSION: As the simplest and the least morbid procedure, endoscopic stone retrieval should be attempted in the treatment of patients with Bouveret's syndrome.When it fails, surgical lithotomy consisting of simple enterotomy may solve the problem. Although cholecystectomy and cholecystoduodenal fistula breakdown is unnecessary in every case, conditions may urge the surgeon to perform such operations even though they carry high morbidity and mortality. | Rasim Gencosmanoglu Resit Inceoglu Caglar Baysal Sertac Akansel Nurdan Tozun | 2003 | World Journal of Gastroenterology2003，9，12： | 9 |
| 2 | Palliation of malignant esophageal obstruction and fistulas with self expandable metallic stents显示文摘AIM: To evaluate the efficacy of self expandable metallic stents (SEMS) in patients with malignant esophageal obstruction and fistulas. METHODS: SEMS were implanted in the presence of fluoroscopic guidance in patients suffering from advanced and non-resectable esophageal, cardiac and invasive lung cancer between 2002 and 2009. All procedures were performed under conscious sedation. All patients had esophagus obstruction and/or fistula. In all patients who required reintervention, recurrence of dysphagia, hemorrhage, and fistula formation were indications for further endoscopy. Patients' files were scanned retrospectively and the obtained data were analyzed using SPSS 13.0 for Windows. The χ 2 test was used for categorical data and was analysis of variance for noncategorical data. Patients' long-term survival was assessed using the Kaplan-Meier method. RESULTS: Stents were successfully implanted in 90 patients using fluoroscopic guidance. Reasons for stent implantation in these patients were esophageal stricture (77/90, 85.5%), external pressure (8/90, 8.8%) and tracheo-esophageal fistula (5/90, 5.5%). Dysphagia scores (mean ± SD) were 3.37 ± 0.52 before and 0.90 ± 0.43 after stent implantation (P = 0.002). Intermittent, nonmassive hemorrhage due to the erosion caused by the distal end of the stent in the stomach occurred in only one patient who received implementation at cardioesophageal junction. Mean survival following stenting was 134.14 d (95% confidence interval: 94.06-174.21).CONCLUSION: SEMS placement is safe and effective in the palliation of dysphagia in selected patients with malignant esophageal strictures. | Ahmet Dobrucali Erkan Caglar | 2010 | World Journal of Gastroenterology2010，16，45： | 9 |
| 3 | A bibliometric analysis of academic publication on diabetic retinopathy disease trends during 1980-2014:a global and medical view显示文摘·AIM: To investigate diabetic retinopathy(DR) literature using the Institute for Scientific Information(ISI) Web of Science(Wo S) database and to analyse the correlation results between socio-economic development datas and number of DR publications.·METHODS: The statistical analysis of the documents published during 1980-2014 was analysed. The data of this study were based on the database of Wo S. 'Diabetic retinopathy' was used as the keywords to search the Wo S database.·RESULTS: The United States ranked first in the DR research with 1840 publications and 24.38% of the world production followed by England and Japan. Besides, the most productive country was Iceland. A high correlation was found between number of publications and 2014 gross domestic product( GDP) values of 81 countries(r =0.800, P <0.001). We found a significant correlation between number of publications and Human Development Index(HDI)(r =0.645, P =0.001). There is a moderate correlation between people with diabetes and number of DR publications for 81 countries(r =0.514, P <0.01). It could be analysed that estimated publication number with DR title will be 445 according to the regression curve constituted with cubic model in 2015(R2=1.000).·CONCLUSION: More DR studies have been published in developed countries, DR and other complications of diabetes have gradually increased in developing countries over recent decades. It can be expected that the number of DR studies will gradually increase in developing countries. | Cagatay Caglar Emre Demir Ferit Kerim Kucukler Mustafa Durmus | 2016 | International Journal of Ophthalmology(English edition)2016，9，11： | 7 |
| 4 | Effect of BMI on outcomes of surgical treatment for tibial plateau fractures: A comparative retrospective case series study显示文摘 | Yasar Mahsut Dincel All Oner Yavuz Arikan Sever Caglar Rasit Ozcafer Mehmet Akif Gulec | 2018 | Chinese Journal of Traumatology2018，21，2： | 7 |
| 5 | Re-adhesion control strategy based on the optimal slip velocity seeking method显示文摘In the railway industry, re-adhesion control plays an important role in attenuating the slip occurrence due to the low adhesion condition in the wheel–rail interaction. Braking and traction forces depend on the normal force and adhesion coefficient at the wheel–rail contact area. Due to the restrictions on controlling normal force,the only way to increase the tractive or braking effect is to maximize the adhesion coefficient. Through efficient utilization of adhesion, it is also possible to avoid wheel–rail wear and minimize the energy consumption. The adhesion between wheel and rail is a highly nonlinear function of many parameters like environmental conditions, railway vehicle speed and slip velocity. To estimate these unknown parameters accurately is a very hard and competitive challenge. The robust adaptive control strategy presented in this paper is not only able to suppress the wheel slip in time, but also maximize the adhesion utilization performance after re-adhesion process even if the wheel–rail contact mechanism exhibits significant adhesion uncertainties and/or nonlinearities. Using an optimal slip velocity seeking algorithm, the proposed strategy providesa satisfactory slip velocity tracking ability, which was demonstrated able to realize the desired slip velocity without experiencing any instability problem. The control torque of the traction motor was regulated continuously to drive the railway vehicle in the neighborhood of the optimal adhesion point and guarantee the best traction capacity after re-adhesion process by making the railway vehicle operate away from the unstable region. The results obtained from the adaptive approach based on the secondorder sliding mode observer have been confirmed through theoretical analysis and numerical simulation conducted in MATLAB and Simulink with a full traction model under various wheel–rail conditions. | Caglar Uyulan Metin Gokasan Seta Bogosyan | 2018 | Journal of Modern Transportation2018，26，1： | 4 |
| 6 | Clinical evaluation of implants in patients with maxillofacial defects显示文摘AIM: To show the efficacy of reconstruction and rehabilitation of large acquired maxillofacial defects due to tumor resections and firearm injuries. METHODS: The study group comprised of 16 patients(10 men and 6 women) who were operated on because of their maxillofacial defects under local and general anesthesia between June 2007 and June 2011. Prosthetic treatment with the aid of dental implants was performed for all of the patients. Eight patients received an implant supported fixed prosthesis; six patients received implant supported overdentures and two patients received both. Patients were followed up postoperatively for 1 to 4 years. Implant success and survival rates were recorded. Panoramic radiographs were taken preoperatively, immediately after surgery, immediately after loading and at every recall session. Peri-implant and prosthetic complications were recorded. Subjects were asked to grade their oral health satisfaction after treatment according to 100 mm visual analog scale(VAS) and the oral health related quality oflife of the patients was measured with the short-form Oral Health Impact Profile. RESULTS: Five implants(3 in the mandible, 2 in the maxilla) in five patients were lost, while the other 53 survived, which brings an overall survival rate of 91.37% on the implant basis, but 68.75% on patient basis. All the failed implants were lost before abutment connection and were therefore regarded as early failures. For all failed implants, new implants were placed after a 2 mo period and the planning was maintained. The mean marginal bone loss(MBL) was 1.4 mm on the mesial side and 1.6 mm on the distal side of the implants. Five of the implants showed MBL > 2 mm(mean MBL = 2.3 mm) but less than 1/2 of the implant bodies and therefore were regarded as not successful but surviving implants. The VAS General Comfort mean score was 85.07, the VAS Speech mean score was 75.25 and the VAS Esthetics mean score was 82.74. No patient reported low scores(score lower than 50) of satisfaction in any of the evaluated factors. The mean of OHIP-14 scores was 5.5. CONCLUSION: Although further follow up and larger case numbers will give more information about the success of dental implants as a treatment modality in maxillofacial defects patients, the actual results are encouraging and can be recommended for similar cases. | Belir Atalay Hakan Bilhan Onur Geckili Caglar Bilmenoglu Ugur Meric | 2013 | World Journal of Stomatology2013，2，3： | 3 |
| 7 | Neuroprotective effect of edaravone in experimental glaucoma model in rats: a immunofluorescence and biochemical analysis显示文摘AIM: To evaluate the neuroprotective activity of systemically administered edaravone in early and late stage of experimental glaucoma in rats.METHODS: In this study, 60 Wistar albino rats were used. Experimental glaucoma model was created by injecting hyaluronic acid to the anterior chamber once a week for 6wk in 46 of 60 subjects. Fourteen subjects without any medication were included as control group.Edaravone administered intraperitoneally 3 mg/kg/d to the 15 of 30 subjects starting at the onset of glaucoma induction and also administered intraperitoneally3 mg/kg/d to the other 15 subjects starting at three weeks after the onset of glaucoma induction. The other16 subjects who underwent glaucoma induction was administered any therapy. Retinal ganglion cells(RGCs)have been marked with dextran tetramethylrhodamine(DTMR) retrograde at the end of the sixth week and after48 h, subjects were sacrificed by the method of cardiac perfusion. Alive RGC density was assessed in the wholemount retina. Whole-mount retinal tissues homogenized and nitric oxide(NO), malondialdehyde(MDA) and total antioxidant capacity(TAC) values were measured biochemically.RESULTS: RGCs counted with Image-Pro Plus program, in the treatment group were found to be statistically significantly protected, compared to the glaucoma group(Bonferroni,P <0.05). The neuroprotective activity of edaravone was found to be more influential byadministration at the start of the glaucoma process.Statistically significant lower NO levels were determined in the glaucoma group comparing treatment groups(Bonferroni, P <0.05). MDA levels were found to be highest in untreated glaucoma group, TAC levels were found to be lower in the glaucoma induction groups than the control group(Bonferroni, P <0.05).CONCLUSION: Systemic administration of edaravone in experimental glaucoma showed potent neuroprotective activity. The role of oxidative stress causing RGC damage in glaucoma was supported by this study results. | Arzu Toruk Aksar Nursen Yuksel Mustafa Gok Mustafa Cekmen Yusuf Caglar | 2015 | International Journal of Ophthalmology(English edition)2015，8，2： | 2 |
| 8 | Familial chylomicronemia syndrome related chronic pancreatitis: a single-center study显示文摘BACKGROUND: Hypertriglyceridemia induces acute recurrent pancreatitis, but its role in the etiology of chronic pancreatitis(CP) is controversial. This study aimed to evaluate the clinical laboratory and radiological findings of 7 patients with CP due to type 1 hyperlipidemia compared to CP patients with other or undefined etiological factors.METHODS: We retrospectively analyzed the clinical, laboratory and radiological findings of 7 CP patients with type 1 hyper lipidemia compared to CP patients without hypertriglyceridemia These 7 patients had multiple episodes of acute pancreatitis and had features of CP on abdominal CT, endoscopic retrograde cholangiopancreatography and/or endoscopic ultrasonography.RESULTS: All CP patients were classified into two groups: a group with type 1 hyperlipidemia (n=7) and a group with other etiologies (n=58). The mean triglyceride level was 2323±894mg/dL in the first group. Age at the diagnosis of CP in the first group was significantly younger than that in the second group(16.5±5.9 vs 48.3±13.5, P<0.001). The number of episodes of acute pancreatitis in the first group was significantly higher than that in the second group (15.0±6.8 vs 4.0±4.6, P=0.011)The number of splenic vein thrombosis in the first group was significantly higher than that in the second group (4/7 vs 9/58P=0.025). Logistic regression analysis found that younger age was an independent predictor of CP due to hypertriglyceridemia(r=0.418, P=0.000).CONCLUSIONS: Type 1 hyperlipidemia appears to be an etiological factor even for a minority of patients with CP. It manifests at a younger age, and the course of the disease might be severe. | Gurhan Sisman Yusuf Erzin Ibrahim Hatemi Erkan Caglar Salih Boga Vikesh Singh Hakan Senturk | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，2： | 2 |
| 9 | Results of concurrentchemoradiotherapy with low dose weekly gemcitabine in sage m non small celllung cancer 显示文摘 | Abacioglu V Yumuk PF Caglar H | 2004 | Asco2004，23，： | 1 |
| 10 | Microstructure and electro-optical properties of sol-gel derived Cd-doped ZnO films 显示文摘 | Yakuphanoglu F Ilican S Caglar M | 2010 | Supedattice Microst2010，47，： | 1 |
| 11 | Effects of different ceramic and composite materials on stress distribution in inlay and onlay cavities:3-D finite element analysis显示文摘 | Yamanel K Caglar A Gülsahi K | | 0，，06： | 1 |
| 12 | Tracking Refractivity from Clutter Using Kalman and Particle Filters显示文摘 | Caglar Yardim Peter Gerstoft WILLIAM S | | 0，，4： | 1 |
| 13 | Comparison of hematologic toxicity between 3DCRT and IMRT planning in cervical cancer patients afterconcurrent chemoradiotherapy: a national multi-center study显示文摘 | Erpolat OP Alco G Caglar HB | 2014 | Gynaeeol Oneol2014，35，1： | 1 |
| 14 | A generalized parametric PR-QMF design technique based on Bernstein polynomial approximation显示文摘 | Caglar H Akansu A N | 1993 | IEEE Transactions on Signal Processing1993，41，7： | 1 |
| 15 | Adiponectin level isreduced and inversely correlated with the degree of proteinuria in type 2 dia- betic patients 显示文摘 | Ynicesu M Yilmaz MI Caglar K | 2005 | Clin Nephrol2005，64，1： | 1 |
| 16 | Wind power engineering in the world and perspectives of its development in Turkey 显示文摘 | Kenisarin Murat Karsli Vedat M Caglar Mehmet | 2006 | Renewable and Sustainable Energy Reviews2006，10，4： | 1 |
| 17 | An unusual radiographic finding in pulmonary parenchymal endometriosis显示文摘 | Kiyan E Kilicaslan Z Caglar E | 2002 | Acta Radiol2002，43，： | 1 |
| 18 | Therapeutic effects of oral nutrition supplementation during hemodialysis 显示文摘 | Caglar C Fedje L Dimmitt R | 2002 | Kidney Inter2002，62，1： | 1 |
| 19 | Comparison of com- pression plate and flexible intramedullary nail fixation in pediatric femoral shaft fractures显示文摘 | CAGLAR O AKSOY M C YAZICI M | 2006 | J Pediatr Orthop B2006，15，3： | 1 |
| 20 | 'Reading man flap' design for recon- struction of circular infraorbital and malar skin defects 显示文摘 | Seyhan T Caglar B | 2008 | Dermatol Surg2008，34，11： | 1 |
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