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| 1 | Malaria Surveillance of Entry People During the COVID-19 Epidemic—Guangdong Province,China,October 2020–May 2021显示文摘Summary What is already known about this topic?Malaria control was affected by the coronavirus disease 2019(COVID-19)pandemic.This study conducted active case finding for key flights and key populations to determine malaria transmission.What is added by this report?Surveillance for malaria was conducted for entry personnel coming from areas affected by malaria.It is estimated that at least 100,000 tests were conducted in Guangdong Province. | De Wu Zhuohui Deng Rongxin Lin Qiang Mao Wenchen Lu Caiwen Ruan Yongzhen Cen Ning Xiao Tie Song | 2021 | China CDC weekly2021,3,38: | 2 |
| 2 | Fabrication of Tβ4-Exosome-releasing artificial stem cells for myocardial infarction therapy by improving coronary collateralization显示文摘Currently,stem cell transplantations in cardiac repair are limited owing to disadvantages,such as immunological rejection and poor cell viability.Although direct injection of exosomes can have a curative effect similar to that of stem cell transplantation,high clearance hinders its application in clinical practice.Previous reports suggested that induction of coronary collateralization can be a desired method of adjunctive therapy for someone who had missed the optimal operation time to attenuate myocardial ischemia.In this study,to mimic the paracrine and biological activity of stem cells,we developed artificial stem cells that can continuously release Tβ4-exosomes(Tβ4-ASCs)by encapsulating specific exosomes within microspheres using microfluidics technology.The results show that Tβ4-ASCs can greatly promote coronary collateralization in the periphery of the myocardial infarcted area,and its therapeutic effect is superior to that of directly injecting the exosomes.In addition,to better understand how it works,we demonstrated that the Tβ4-ASC-derived exosomes can enhance the angiogenic capacity of coronary endothelial cells(CAECs)via the miR-17-5p/PHD3/Hif-1αpathway.In brief,as artificial stem cells,Tβ4-ASCs can constantly release functional exosomes and stimulate the formation of collateral circulation after myocardial infarction,providing a feasible and alternative method for clinical revascularization. | Peier Chen Xiaodong Ning Weirun Li Yuxuan Pan Ling Wang Hekai Li Xianglin Fan Jiexin Zhang Tiantian Luo Yaobin Wu Caiwen Ou Minsheng Chen | 2022 | Bioactive Materials2022,7,8: | 2 |
| 3 | Past and recent advances in sugarcane cytogenetics显示文摘The Saccharum genus comprises species with large and variable chromosome numbers, leading to challenges in genomic studies and breeding improvement. Cytogenetics, including classical and molecular approaches, has played a central role in deciphering the genome structure, classification, and evolution of the genus Saccharum. The application of fluorescence in situ hybridization using oligonucleotide probes significantly improved our understanding of the complex genomes of Saccharum species. This paper reviews the application and progress of cytogenetic techniques in Saccharum. Future applications of cytogenetics are discussed, as they could benefit both genomic studies and breeding of sugarcane as well as other plants with complex genomes. | Kai Wang Hui Zhang Haris Khurshid Ayman Esh Caiwen Wu Qinnan Wang Nathalie Piperidis | 2023 | The Crop Journal2023,11,1: | 0 |
| 4 | Effects of Colchicine on Callus Induction and Differentiation of Erianthus arundinaceus显示文摘Erianthus arundinaceum,a related species of the most important sugar crop Saccharum,and is an essential gene resource for stress and disease resistance in sugarcane breeding. Colchicine is the most common and effective chemical inducer in polyploid breeding at present. To detect the effects of colchicine on callus induction and shoot regeneration,E. arundinaceus‘Yun 83-183',with the chromosome of 2 n = 60,was used as the material for studying the effect of different concentrations of 2,4-D and colchicine,treatment time and culture methods on callus induction and shoot regeneration. The results indicated,when the callus was cultured for 7 d in solid medium with 0. 07% colchicine or 0. 5 d in liquid medium with 0. 05% colchicine,callus had no ability of shoot regeneration,which meant that in liquid culture,colchicine had not only high inhibitory effect on callus,but also lower concentration and shorter treatment time than solid culture;when the concentration of colchicine was 0. 03% and callus was cultured for 7 d in solid medium or 0. 5 d in liquid medium,the resistant callus rate and resistant bud rate were the highest,although the resistant callus rates were all about 88. 00% and had no significant difference between solid culture and liquid culture,the resistance bud rate was only 6. 00% in liquid culture,16. 22% lower than in solid culture,which meant that solid culture was more effective than liquid culture at the same colchicine concentration. For E. arundinaceus ‘Yun 83-183',the best concentration of 2,4-D was 2 mg/L,the best concentration of colchicine was 0. 03%,and the best effect of callus induction and shoot regeneration was achieved within 7 d of solid culture. This study would provide fundamental information for chromosome doubling of E. arundinaceus in the future. | Li YAO Peifang ZHAO Jun ZHAO Jiayong LIU Wei QIN Caiwen WU | 2018 | Agricultural Biotechnology2018,7,1: | 0 |