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2篇 您的检索式:作者名="Cancan Lv"
    题名 作者 年代 出处 被引量
1Ten-year Etiologic Review of Chinese Children Hospitalized for Pediatric Cataracts显示文摘Purpose:Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.Methods:.Medical records accrued over a 10-year period(from August, 2003 to July, 2013) at Shengjing Hospital of China Medical University were reviewed retrospectively,ide ntifying all patients treated for various subtypes of pediatric cataract..A database with 367 subjects under 14 years of age(598, including second-round surgeries) was generated.Results:.Of this cohort(n =367; males: 232, 63.2%; females: 135, 36.8%), 200 patients(54.5%) had bilateral cataracts,and 258(70.3%) were under 3 years of age. In all age groups and in all subtypes of pediatric cataract,.males were most commonly affected..Congenital cataract was the most prevalent subtype, accounting for 296 patients(80.7%). Most congenital cataracts were associated with other ocular or systemic abnormalities;.and in 48 patients(16.22%),.they were hereditary..Traumatic cataract was the most common subtype(85.92%) of acquired cataract. The few instances of cataracts due to steroids(n=3) or to metabolic disorders(n=2) occurred in males and involved both eyes.Conclusion: The majority of pediatric cataracts in this patient population were congenital in nature. A significant lag in ophthalmologic evaluation of Chinese infants was evident and should be addressed by educating both children and parents on risk factors for cataract development. Regular assessments are especially important in children subjected to long-term systemic steroid treatments.Zixun Song Daixin Zhao Cancan Lv Wei Pu Wei Xiao 2014Eye Science2014,29,3:1
2Clinical Analysis of the Incidence and the Treatment of Pediatric Cataract Patients with Optic-nerve Maldevelopment显示文摘Purpose: To interpret the incidence of optic-nerve maldevelopment in postoperative pediatric cataract patients, and evaluate the clinical efficacy of administration of murine nerve growth factor(mNGF) in such patients.Methods: Pattern visual evoked potential(P-VEP) was used to measure the visual pathway function in 28 cases(56 eyes)with bilateral congenital cataract and 13 cases(13 eyes) with unilateral congenital cataract who underwent cataract extraction and intraocular lens implantation surgeries. The results were compared with 25 age-sex-matched healthy children(50eyes). mNGF was administered in 13 cases(23 eyes) who had visual pathway disorder. The efficacy of mNGF injection was observed. P100 latencies, which were used as a main parameter in P-VEP measurement, were analyzed statistically.Results: When compared with normal children, the P100 latency was significantly prolonged in the congenital cataract group(P<0.05). A significant improvement was noted in the visual pathway of subjects treated with mNGF(P<0.05).Conclusion: Compared with normal children, the congenital cataract patients are more vulnerable to optic-nerve maldevelopment. Murine NGF likely plays a protective and nutritive role in the development of optic nerve in cases of optic-nerve maldevelopment followed by congenital cataract surgery.Cancan Lv Wei Xiao 2014Eye Science2014,29,1:0
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