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| 1 | Coronary microvascular dysfunction in diabetes mellitus:A review显示文摘The exploration of coronary microcirculatory dysfunction in diabetes has accelerated in recent years.Cardiac function is compromised in diabetes.Diabetic patients manifest accelerated atherosclerosis in coronary arteries.These data are confirmed in diabetic animal mod-els,where lesions of small coronary arteries have been described.These concepts are epitomized in the classic microvascular complications of diabetes,i.e.blindness,kidney failure and distal dry gangrene.Most importantly,accumulating data indicate that insights gained from the link between inflammation and diabetes can yield predictive and prognostic information of considerable clinical utility.This review summarizes the evidence for the predisposing factors and the mechanisms involved in diabetes,and assesses the current state of knowledge regarding the triggers for inflammation in this disease.We evaluate the roles of hyperglycemia,oxidative stress,polyol pathway,protein kinase C,advanced glycation end products,insulin resistance,peroxisome proliferator-activated receptor-γ,inflammation,and diabetic cardiomyopathy as a 'stem cell disease'.Furthermore,we discuss the mechanisms responsible for impaired coronary arteriole function.Finally,we consider how new insights in diabetes may provide innovative therapeutic strategies. | Andrea Picchi Stefano Capobianco Marta Focardi | 2010 | World Journal of Cardiology2010,2,11: | 24 |
| 2 | Endothelial progenitor cells as factors in neovascularization and endothelial repair显示文摘Endothelial progenitor cells(EPCs)are a heterogeneous population of cells that are provided by the bone marrow and other adult tissue in both animals and humans.They express both hematopoietic and endothelial surface markers,which challenge the classic dogma that the presumed differentiation of cells into angioblasts and subsequent endothelial and vascular differentiation occurred exclusively in embryonic development.This breakthrough stimulated research to understand the mechanism(s)underlying their physiologic function to allow development of new therapeutic options.One focus has been on their ability to form new vessels in injured tissues,and another has been on their ability to repair endothelial damage and restore both monolayer integrity and endothelial function in denuded vessels.Moreover,measures of their density have been shown to be a better predictor of cardiovascular events,both in healthy and coronary artery disease populations than the classical tools used in the clinic to evaluate the risk stratification.In the present paper we review the effects of EPCs on revascularization and endothelial repair in animal models and human studies,in an attempt to better understand their function,which may lead to potential advancement in clinical management. | Stefano Capobianco Venu Chennamaneni Mayank Mittal | 2010 | World Journal of Cardiology2010,2,12: | 7 |
| 3 | Smart cities and urban networks:are smart networks what we need?显示文摘Metropolitan areas have become very important subjects at political,social and economic levels.They draw information from sources of data and official statistics aimed to operate classification in a quite static way.In parallel,the idea of a smart city has been largely promoted in recent years,becoming a paradigm of continuous transformation.However,cities have been called smart in so many ways that it is almost impossible to formulate any generally accepted prioritization.Owing to the role of social media,which is now dominant in modern societies,we evaluate the impact of urban networks in the metropolitan area context.In particular,we revisit the latter in light of the functions of networks referred to transportation systems and‘big data’associated to them.We measure the impact of both transportation networks and big data networks,establishing their centrality and addressing the current needs. | Nicola Ianuale Duccio Schiavon Enrico Capobianco | 2015 | Journal of Management Analytics2015,2,4: | 3 |
| 4 | 高血压患者同型半胱氨酸水平升高与代谢综合征和心血管事件相关显示文摘高同型半胱氨酸(homocysteine,Hcy)血症和代谢综合征(metabolic syndrome,MS)是明确的心血管危险因素,常与高血压相关。然而血浆Hcy与MS、胰岛素抵抗相关性存在争议,且在高血压患者中的研究较少。该研究探讨高血压患者Hcy与MS和心脑血管事件的相关性。 | Catena C Colussi G Nait F Capobianco F Sechi LA 陈云 叶鹏 | 2016 | 中华高血压杂志2016,24,1: | 2 |
| 5 | Increased matrix metalloproteinases 2 and 9 in placenta of diabetic rats at midgestation显示文摘 | Pustovrh MC Jawerbaum A Capobianco E | 2005 | Placenta2005,26,4: | 1 |
| 6 | Induction of cyclin D1 transcription and CDK2 activity by Notch(ic):implication for cell cycle disruption in transformation by Notch(ic)显示文摘 | Ronchini C Capobianco AJ | 2001 | Mol Cell Biol2001,21,17: | 1 |
| 7 | Long-term outcome of hyst- eroscopic endometrial ablation without endometrial preparation 显示文摘 | Rosati M Vigone A Capobianco F | 2008 | Eur J Obstet Gynecol Reprod Bio12008,138,2: | 1 |
| 8 | Human cleavage-stage embryo vitrification is comparable to slow-rate cryopreservation in cycles of assisted reproduction显示文摘 | Wilding M Capobianco C Montanaro N | 2010 | J Assist Reprod Genet2010,27,: | 1 |
| 9 | A summary of European experience with shore nourishment显示文摘 | L Hamm M Capobianco H.H Dette A Lechuga R Spanhoff M.J.F Stive | 2002 | Coastal Engineering2002,,2: | 1 |
| 10 | A second hysterosalpingography reduces the use of selective technique for treatment of a proximal tubal obstruction显示文摘 | Dessole S Meloni GB Capobianco G | 2000 | Fertil Steril2000,73,5: | 1 |
| 11 | Endometriosis, a disease of the maerophage 显示文摘 | Capobianco A Rovere-Querini P | 2013 | From Immuno12013,4,: | 1 |
| 12 | Facial pain显示文摘 | Hentschel K Capobianco DJ Dodick DW | 2005 | Neurologist2005,11,3: | 1 |
| 13 | 15-Deoxy-Delta (12,14)-prostaglandin J2 and peroxisome proliferator-activated receptor gamma (PPARgamma) levels in term placental tissues from control and diabetic rats:modulatory effects of a PPARgamma agonist on nitridergic and lipid placental metabolism显示文摘 | Capobianco E Jawerbaum A Romanini MC | 2005 | Reprod Fertil Dev2005,17,4: | 1 |
| 14 | Increased matrix Metalloproteinases 2 and 9 in placenta of diabetic rats at midgestation显示文摘 | Pustovrh MC Jawerbaum A Capobianco E | 2005 | Placenta2005,26,4: | 1 |
| 15 | Mesenchy- mal stem cell-natural killer cell interactions:evidence that acti- vated NK cells are capable of killing MSCs,whereas MSCs can inhibit IL-2-induced NK-cell proliferation显示文摘 | Spaggiari GM Capobianco A Becchetti S | 2006 | Blood2006,107,4: | 1 |
| 16 | Visible upconversion of Er 3+ doped nanocrystalline and bulk Lu 2 O 3显示文摘 | J.A Capobianco F Vetrone J.C Boyer A Speghini M Bettinelli | 2002 | Optical Materials2002,,: | 1 |
| 17 | Intratympanic dexamethasone treatment for control of subjective idiopathic tinnitus: our clinical experience 显示文摘 | CESARANI A CAPOBIANCO S SOI D | 2002 | Int Tinnitus J2002,8,: | 1 |
| 18 | Isobaric gasless laparoscopy versus minilaparotomy in uterine myomeetomy : a randomized trial 显示文摘 | Sesti F Capobianco F Capozzolo T | 2008 | Surg Endosc2008,22,4: | 1 |
| 19 | Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia显示文摘 | Demarest RM Dahmane N Capobianco AJ | | 0,,10: | 1 |
| 20 | Significance of Yb3 concentration on the upconversion mechanisms in codoped Y2O3:Er3,Yb3 nanocrystals显示文摘 | VETRONE F BOYER J C CAPOBIANCO J A | 2004 | J Appl Phys2004,,96: | 1 |