维普期刊资源整合服务平台（V6.5）

55篇 您的检索式：作者名="Capsoni A"

选中清除导出查看参考文献查看引证文献引用追踪共3页首页上一页第1页下一页末页 /3 跳转

	题名	作者	年代	出处	被引量
1	神经生长因子增强小胶质细胞的神经保护作用显示文摘小胶质细胞是脑组织内的防御细胞,但在病理和生理条件下,调控小胶质细胞活化的因子并不十分清楚。本研究发现,神经生长因子(NGF)可以增强小胶质细胞的神经保护和抗炎功能。在体内和体外研究中都发现,小胶质细胞表达NGF受体。原代培养小胶质细胞,给予NGF处理,转录本分析结果显示,NGF对小胶质细胞的运动、吞噬和降解吞噬物的能力均产生影响。对功能的研究显示,NGF可增加小胶质细胞的膜运动能力和胞饮作用;在体研究显示,NGF可激活小胶质细胞释放向外整流电流,调节周围谷氨酸能神经元的神经传递。既往研究提示,小胶质细胞有清除脑内Aβ肽的功能,本研究观察了NGF对小胶质细胞吞噬能力的影响。结果显示,NGF可促进小胶质细胞通过Trk A途径清除Aβ,并加速其降解。此外,NGF还可减轻由Aβ导致的炎症激活。特异性激活小胶质细胞还可以减轻由Aβ导致的神经元树突损伤和长时程增强抑制。在对离体脑片的研究中,我们也发现NGF可以促进小胶质细胞吞噬Aβ。综上所述,本研究证实NGF可以促进小胶质细胞活化,活化的小胶质细胞通过抗炎作用减轻Aβ聚集,发挥神经保护作用。	唐颖馨 Rizzi C Tiberi A Giustizieri M Marrone MC Gobbo F Carucci NM Meli G Arisi I D'Onofrio M Marinelli S Capsoni S Cattaneo A	2018	神经损伤与功能重建2018，13，2：	2
2	Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice 显示文摘	CAPSONI S GIANNOTTA S CATTANEO A	2002	Proc Natl Acad Sci USA2002，99，12：	1
3	Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice 显示文摘	Capsoni S Ugolini G Comparini A	2000	Proc Natl Acad Sci USA2000，97，12：	1
4	Evaulation of the kinetics of the imunomodulation activity of pidotimod on human显示文摘	F Minonzio A Mongari	1992	Neutrophils pharmacol Res1992，26，2：	1
5	Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice显示文摘	Capsoni S Giannotta S Cattanco A	2002	Proc Natl Acad Sci USA2002，99，12：	1
6	The neuropeptide α-MSH has specific receptors on neutrophils and reduces chemotaxis in vitro 显示文摘	Catania A Rajora N Capsoni F	1996	Peptides1996，17，4：	1
7	Nerve growth factor regulates axial rotation during early stages of chick embryo development显示文摘	Manca A Capsoni S Di Luzio A	2012	Proc Natl Acad Sci USA2012，109，6：	1
8	Nerve growthfactor regulates axial rotation during early stages of chickembryo development显示文摘	Manca A Capsoni S Di Luzio A	2012	Proc Natl Acad Sci U S A2012，109，6：	1
9	A small molecule targeting the multifactorial nature of Alzheimer's disease显示文摘	Cavalli A Bolognesi ML Capsoni S		0，，20：	1
10	A small molecule targeting the multifactorial nature of Alzheimer's disease显示文摘	CAVALLI A BOLOGNESI M L CAPSONI S	2007	Angew Chem Int Ed Engl2007，46，20：	1
11	On the molecular basis linking nerve growthfactor(NGF)to Alzheimer’s disease显示文摘	Capsoni S Cattaneo A	2006	Cell Mol Neurobiol2006，2，6：	1
12	Dark rearing blocks the developmental down-regulation of brain-derived neurotrophic factor messenger RNA expression in layers Ⅳ and Ⅴ of the rat visual cortex显示文摘	Capsoni S Tongiorgi E Cattaneo A	1999	Neuroscience1999，88，2：	1
13	Differential regulation of brain-derived neurotrophic factor messenger RNA cellular expression in the adult rat visual cortex显示文摘	Capsoni S Tongiorgi E Cattaneo A	1999	Neuroscience1999，93，3：	1
14	Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice显示文摘	Capsoni S Ugolini G Comparini A et a1	2000	Pro Nal Acad Sci2000，97，：	1
15	Alzheimer-like neyrodegeneration in aged antinerve growth factor transgenic mice显示文摘	Capsoni S Ugolini G Comparini A	2000	Prod Natl Acad Sci USA2000，97，12：	1
16	Phenotypic knock out of nerve growth factor in adult transgenic mice reveals severe deficit s in basal forebrain cholinergic neurons cell death in the spleen and skeletal muscle dystrophy 显示文摘	Ruberti F Capsoni S Comparini A	2000	J Neurosci2000，20，7：	1
17	A limit analysis study to interpret the ultimate behavior of bolted joints 显示文摘	Aceti R Ballio G Capsoni A	2004	Journal of Constructional Steel Research2004，60，9：	1
18	Nerve growth factor regulates axial rotation during early stages of chick embryo development 显示文摘	Manca A Capsoni S Di Luzio A	2012	Proc Natl Acad Sci U S A2012，109，6：	1
19	Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice显示文摘	Capsoni S Giannotta S Cattaneo A	2002	Proc Natl Acad Sci USA2002，99，12：	1
20	Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti- nerve growth factor mice 显示文摘	Capsoni S Giannotta S Cattaneo A	2002	Proc Nat Acad Sci USA2002，99，12：	1

返回顶部每页显示：

共3页首页上一页第1页下一页末页 /3 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示