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您的检索式：作者名="Cari Whyne"
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| 1 | 整合素α5和肌动蛋白在周期性压力下椎间盘细胞中的表达显示文摘目的探讨整合素α5和肌动蛋白在周期性压力下椎间盘细胞中的表达。方法对猪椎间盘组织进行体外细胞的分离和培养,对细胞施加周期性液压,通过对细胞的形态学观察、Western免疫印迹和免疫组化染色,分别检测整合素α5和肌动蛋白在周期性压力下椎间盘细胞中的表达。结果经加压后,纤维环细胞和髓核细胞均可见体积缩小,由多角形转变为细长形,整合素α5和肌动蛋白在纤维环细胞和髓核细胞中的表达均明显减少。结论体外培养的单层椎间盘细胞在受力状态下,整合素α5的表达减少,整合素α5将力信号转换到细胞内时,进一步影响到与其关系密切的肌动蛋白。这可能是椎间盘细胞力学传导的重要机制。 | 于胜吉 邱贵兴 Yang Burton Roth Sandra Whyne Cari Yee Albert | 2005 | 中华外科杂志2005，43，24： | 1 |
| 2 | Effect of the pedicle and posterior arch on vertebral body strength predieions in finite element modeling 显示文摘 | WHYNE CARI M D H U | 1998 | Spine1998，23，8： | 1 |
| 3 | A comparison of financial and operational efficiency between smart and traditional insufflation for laparoscopic surgery: A granular analysis显示文摘Objective:Smart insufflation(SI)techniques relying on valve and membrane-free insufflation are increasing in usage.Although considerable literature exists demonstrating the benefits of SI on procedural ease and patient outcomes,there remains a paucity describing the financial impact of these devices.The purpose of this study was to determine the financial and efficiency impact of these devices on the operating room and inpatient wards of a hospital.Methods:A discrete event simulation model representing a typical mid-sized North American hospital comparing SI to traditional insufflation(TI)was generated.The National Surgical Quality Improvement database from 2015 to 2019 was used to populate the model with data supplemented from the literature.Outcomes included length of stay(LOS),duration of surgery(DOS),annual procedure volume,profit,return on investment(ROI),and gross profit margin(GPM).From the literature review,DOS savings were 10e32 minutes/case,while LOS savings were 0e3 days/case.Results:Implementation of an SI led to an increase in annual throughput of 42e346(4.4%e36.6%)cases for all procedures and 38 to 297(4.3%e33.3%)cases for complex procedures.LOS was found to be decreased by 175e614(18.3%e64.2%)days for all procedures and 231 to 614(35.6%e77.9%)cases for complex procedures with the implementation of an SI.Together,this resulted in an increase in net profit of$104,685 per annum.The ROI of SI over the TI device was>1000%,and the GPM for the TI was 90.0%,while the GPM for the SI was 71.7%.Conclusion:Despite the initial financial investment being greater,the implementation of SI offsets these expenses and yields significant financial benefits.Our study demonstrates the financial benefits of SI over TI and illustrates how granular operational and financial analyses of technologies are essential to aid in sound healthcare procurement decision making. | Aazad Abbas Imran Saleh Graeme Hoit Gurjovan Sahi Sam Park Jihad Abouali Cari Whyne Jay Toor | 2023 | Laparoscopic, Endoscopic and Robotic Surgery2023，6，3： | 0 |
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