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| 1 | 前列腺铥激光摘除术治疗良性前列腺增生患者的性功能结果显示文摘患者继发于良性前列腺增生(B P H) 的下尿路症状(LUTS)的治疗可能影响性功能和射精的质量。新的手术方法治疗良性前列腺增生,对勃起和射精的影响,目前研究甚少。这项研究的目的是评估对继发于前列腺增生的LUTS患者,前列腺铥激光摘除术(ThuLEP)对性功能和逆行射精的影响。我们进行了一项前瞻性研究,收集了连续110例行ThuLEP患者,分析性功能和排尿症状的变化。为了评估勃起、射精变化及排尿症状对生活质量(Qol)的影响,我们使用了五个经验证的问卷:ICIQ-MLUTSsex,MSHQ-EJD,IIFE-5,IPSS,以及Qol调查问卷。患者还经过IPSS和尿流率仪来评估尿流率结果。对患者进行ThuLEP术前和术后3-6个月的评估,而那些有既往腹部手术史的病人被排除在外。患者平均年龄为67.83年。术后排尿症状好转。手术前后的勃起功能没有观察到显著差异。与文献中描述的其他技术相比,患者ThuLEP后保留的射精功能增加了52.7%。 通过对患者问卷调查得分的评估,ThuLEP正面影响排尿症状和的和患者的生活质量。而前列腺增生内镜治疗(如经尿道前列腺电切术),导致大多数患者逆行射精。那些接受ThuLEP治疗的患者保留了射精和勃起功能。 | Luca Carmignani Giorgio Bozzini Alberto Macchi Serena Maruccia Stefano Picozzi Stefano Casellato | 2015 | Asian Journal of Andrology2015，17，5： | 16 |
| 2 | Safety and feasibility of thullium laser transurethral resection of prostate for the treatment of benign prostatic enlargement in overweight patients显示文摘Objective:We aimed to determine safety and feasibility of thulium laser transurethral vapoenucleation of prostate(ThuVEP)for treatment of obese patients affected by benign prostatic hyperplasia(BPH).Methods:We retrospectively analysed data of 452 patients with BPH who underwent ThuVEP from February 2012 to March 2016 in a single center.Patients were divided into three groups according to body mass index(BMI,kg/m^2):Normal weight(18.5≤BMI<25;Group A),overweight(25≤BMI<30;Group B)and obese(BMI≤30;Group C),for a total of 412 patients evaluable for this study.Preoperative total serum prostate-specific antigen(PSA),digital rectal examination of the prostate,transrectal ultrasound(TRUS),renal ultrasound,urine culture,uroflowmetry,International Prostate Symptoms Score(IPSS),and Quality of Life(QoL)score were analyzed.Post-operative complications,hospital stay and days of catheterization,questionnaires and uroflowmetry at 1 and 3 months after surgery were evaluated.Preoperative data,surgical outcomes,complication rate and clinical outcomes were compared between groups.Results:The median age of patients was 69 years(Interquartile Range[IQR 10]).The preoperative median IPSS among groups was 19(IQR 8.75),20(IQR 10),and 18(IQR 10)respectively.At 1 and 3 months of follow-up,this value was 8(IQR 7),8(IQR 4),7(IQR 5)and 5(IQR 6.25),5(IQR 6),6(IQR 5),respectively(all p between groups>0.05).There was no statistically significant difference among three groups as for hospital stay and days of catheterization(p>0.05).Conclusion:Our results showed that ThuVEP was safe and feasible even in overweight patients with substantially enlarged prostate. | Luca Carmignani Maria Chiara Clementi Claudia Signorini Gloria Motta Sebastiano Nazzani Franco Palmisano Elisa De Lorenzis Michele Catellani Alessandro Francesco Mistretta Andrea Conti Valeria Tringali Maria Beatrice Costa Damiano Vizziello | 2019 | Asian Journal of Urology2019，6，3： | 3 |
| 3 | Menopause and cognitive impairment:A narrative review of current knowledge显示文摘A severe impairment of cognitive function characterizes dementia.Mild cognitive impairment represents a transition between normal cognition and dementia.The frequency of cognitive changes is higher in women than in men.Based on this fact,hormonal factors likely contribute to cognitive decline.In this sense,cognitive complaints are more common near menopause,a phase marked by a decrease in hormone levels,especially estrogen.Additionally,a tendency toward worsened cognitive performance has been reported in women during menopause.Vasomotor symptoms(hot flashes,sweating,and dizziness),vaginal dryness,irritability and forgetfulness are common and associated with a progressive decrease in ovarian function and a subsequent reduction in the serum estrogen concentration.Hormone therapy(HT),based on estrogen with or without progestogen,is the treatment of choice to relieve menopausal symptoms.The studies conducted to date have reported conflicting results regarding the effects of HT on cognition.This article reviews the main aspects of menopause and cognition,including the neuroprotective role of estrogen and the relationship between menopausal symptoms and cognitive function.We present and discuss the findings of the central observational and interventional studies on HT and cognition. | Délio Marques Conde Roberto Carmignani Verdade Ana L R Valadares Lucas F B Mella Adriana OrcesiPedro Lucia Costa-Paiva | 2021 | World Journal of Psychiatry2021，11，8： | 3 |
| 4 | Intraperitoneal cancer dissemination: Mechanisms of the patterns of spread显示文摘 | C. Pablo Carmignani Tessa A. Sugarbaker Christina M. Bromley Paul H. Sugarbaker | 2003 | Cancer and Metastasis Reviews2003，，： | 2 |
| 5 | Incidental splenectomy during left radical nephrectomy:reasons and ways to avoid it显示文摘 | Carmignani G Traverso P Corbu C | 2001 | Urol Int2001，67，3： | 1 |
| 6 | The Seldinger technique for difficult transurethral catheterization a gentle alternative to suprapublic puncture显示文摘 | Carmignani G Campodonico F | 2000 | Br J Surg2000，87，： | 1 |
| 7 | Transient finite element analysis of deep penetration laser welding process in a singlepass butt-welded thick steel plate显示文摘 | CARMIGNANI C MARES R TOSELLI G | 1997 | Computer Methods in Applied Mechanics and Engineering1997，179，3： | 1 |
| 8 | Update on chemotherapeuticagents utilized for perioperative in- traperitoneal chemotherapy 显示文摘 | Sugarbaker P H Mora J T Carmignani P | 2005 | Oncol- ogist2005，10，2： | 1 |
| 9 | Surgery for deep endome- triosis : A pathogenesis-oriented approach 显示文摘 | Vercellini P Carmignani L Rubino T | 2009 | Gynecol Obstet Invest2009，68，2： | 1 |
| 10 | Solubilization of tropicamide by hydroxypropyl-beta-cyclodextrin and water-soluble polymers: in vitro/in vivo studies显示文摘 | Cappello B Carmignani C Iervolino M | 2001 | Int J Pharm2001，213，12： | 1 |
| 11 | Video lap- aroscopic excision of a seminal vesicle cyst associated with ipsilateral renal agenesis显示文摘 | Carmignani G Gallucci M Puppo P | 1995 | J Urol1995，153，2： | 1 |
| 12 | Long-term rsults of intrarenal surgery for branched calculi:is such surgery still valid显示文摘 | Rocco F Casu M Carmignani L | 1998 | Br J Urol1998，81，8： | 1 |
| 13 | Update on chemotherapeutic agents utilized for perioperative intraperitoneal chemotherapy显示文摘 | Sugarbaker PH Mora JT Carmignani P | 2005 | Oncologist2005，10，2： | 1 |
| 14 | Transient finite element analysis of deep penetration laser welding process in a singlepass butt-welded thick steel plate显示文摘 | Carmignani C Mares R Toselli G | 1999 | Computer Methods in Applied Mechanics and Engineering1999，179，34： | 1 |
| 15 | Long-term results of intrarenal surgery for branched calculi: is such surgery still valid?显示文摘 | Rocco F Casu M Carmignani L | 1998 | Br J Urol1998，81，： | 1 |
| 16 | Long-term results of intrarenal surgery for branched calculi:is such surgery still valid?显示文摘 | Rocco F Casu M Carmignani L | 1998 | Br J Urol1998，81，： | 1 |
| 17 | Early Continence Recovery after Open Radical Prostatectomy with Restoration of the Posterior Aspect of the Rhabdosphincter显示文摘 | Francesco Rocco Luca Carmignani Pietro Acquati Franco Gadda Paolo Dell’Orto Bernardo Rocco Stefano Casellato Giacomo Gazzano Dario Consonni | 2007 | European Urology2007，，： | 1 |
| 18 | Transient finite element analysis of deep penetration laser welding process in a singlepass butt-welded thick steel plate显示文摘 | C. Carmignani R. Mares G. Toselli | 1999 | Computer Methods in Applied Mechanics and Engineering1999，，3： | 1 |
| 19 | Long-term results of intrarenal surgery for branched calculus:is such surgery still valid显示文摘 | Rocco F Casu M Carmignani L | 1998 | Br Urol1998，81，： | 1 |
| 20 | AMS three piece inflatable implants for erectile dysfunction:a long-term multi-institutional study in 200 consecutive patients显示文摘 | Montorsi F Carmignani G Campo B | 2000 | Eur Urol2000，37，1： | 1 |
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