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| 1 | Use of a combination strategy to improve neuroprotection and neuroregeneration in a rat model of acute spinal cord injury显示文摘Spinal cord injury is a very common pathological event that has devastating functional consequences in patients. In recent years, several research groups are trying to find an effective therapy that could be applied in clinical practice. In this study, we analyzed the combination of different strategies as a potential therapy for spinal cord injury. Immunization with neural derived peptides(INDP), inhibition of glial scar formation(dipyridyl: DPY), as well as the use of biocompatible matrix(fibrin glue: FG) impregnated with bone marrow mesenchymal stem cells(MSCs) were combined and then its beneficial effects were evaluated in the induction of neuroprotection and neuroregeneration after acute SCI. Sprague-Dawley female rats were subjected to a moderate spinal cord injury and then randomly allocated into five groups: 1) phosphate buffered saline; 2) DPY; 3) INDP + DPY; 4) DPY+ FG; 5) INDP + DPY + FG + MSCs. In all rats, intervention was performed 72 hours after spinal cord injury. Locomotor and sensibility recovery was assessed in all rats. At 60 days after treatment, histological examinations of the spinal cord(hematoxylin-eosin and Bielschowsky staining) were performed. Our results showed that the combination therapy(DPY+ INDP + FG+ MSCs) was the best strategy to promote motor and sensibility recovery. In addition, significant increases in tissue preservation and axonal density were observed in the combination therapy group. Findings from this study suggest that the combination theapy(DPY+ INDP + FG + MSCs) exhibits potential effects on the protection and regeneration of neural tissue after acute spinal cord injury. All procedures were approved by the Animal Bioethics and Welfare Committee(approval No. 178544; CSNBTBIBAJ 090812960)on August 15, 2016. | Elisa García Roxana Rodríguez-Barrera Vinnitsa Buzoianu-Anguiano Adrian Flores-Romero Emanuel Malagón-Axotla Marco Guerrero-Godinez Estefanía De la Cruz-Castillo Laura Castillo-Carvajal Monserrat Rivas-Gonzalez Paola Santiago-Tovar Ivis Morales Cesar Borlongan Antonio Ibarra | 2019 | Neural Regeneration Research2019，14，6： | 6 |
| 2 | Coronary artery calcium score on low-dose computed tomography for lung cancer screening显示文摘AIM: To evaluate the feasibility of coronary artery calcium score(CACS) on low-dose non-gated chest CT(ngCCT).METHODS: Sixty consecutive individuals(30 males; 73 ± 7 years) scheduled for risk stratification by means of unenhanced ECG-triggered cardiac computed to-mography(gCCT) underwent additional unenhanced ngCCT. All CT scans were performed on a 64-slice CT scanner(Somatom Sensation 64 Cardiac, Siemens, Germany). CACS was calculated using conventional methods/scores(Volume, Mass, Agatston) as previ-ously described in literature. The CACS value obtained were compared. The Mayo Clinic classification was used to stratify cardiovascular risk based on Agatston CACS. Differences and correlations between the two methods were compared. A P-value < 0.05 was considered sig-nificant.RESULTS: Mean CACS values were significantly higher for gCCT as compared to ngCCT(Volume: 418 ± 747 vs 332 ± 597; Mass: 89 ± 151 vs 78 ± 141; Agatston: 481 ± 854 vs 428 ± 776; P < 0.05). The correlation between the two values was always very high(Volume: r = 0.95; Mass: r = 0.97; Agatston: r = 0.98). Of the 6 patients with 0 Agatston score on gCCT, 2(33%) showed an Agatston score > 0 in the ngCCT. Of the 3 patients with 1-10 Agatston score on gCCT, 1(33%) showed an Agatston score of 0 in the ngCCT. Overall, 23(38%) patients were reclassified in a different car-diovascular risk category, mostly(18/23; 78%) shifting to a lower risk in the ngCCT. The estimated radiation dose was significantly higher for gCCT(DLP 115.8 ± 50.7 vs 83.8 ± 16.3; Effective dose 1.6 ± 0.7 mSv vs 1.2 ± 0.2 mSv; P < 0.01).CONCLUSION: CACS assessment is feasible on ngCCT; the variability of CACS values and the associated re-stratification of patients in cardiovascular risk groups should be taken into account. | Teresa Arcadi Erica Maffei Nicola Sverzellati Cesare Mantini Andrea I Guaricci Carlo Tedeschi Chiara Martini Ludovico La Grutta Filippo Cademartiri | 2014 | World Journal of Radiology2014，6，6： | 4 |
| 3 | Angiostatin inhibits endothelial MMP-2 and MMP-14 expression: A hypoxia specific mechanism of action显示文摘 | Aneta Radziwon-Balicka Corey Ramer Cesar Moncada de la Rosa Barbara Zielnik-Drabik Paul Jurasz | 2012 | Vascular Pharmacology2012，，： | 2 |
| 4 | Te-seeded growth of few-quintuple layer Bi2Te3 nanoplates显示文摘 | Yanyuan Zhao Maria de la Mata Richard L. J. Qiu Jun Zhang Xinglin wen Cesar Magen Xuan P. A. Gao Jordi Arbiol Qihua Xiong | 2014 | Nano Research2014，7，9： | 2 |
| 5 | 热流效应对场向电流确定的影响显示文摘给出了任意速度分布函数条件下复频率的介电函数和色散关系的求解方法.讨论了16矩近似条件下,场向热流对电子速度分布函数,介电函数实部与虚部,以及离子与电子谐振频率和阻尼率的影响,并与平衡态时麦克斯韦分布等离子体的计算结果进行了比较.忽略场向热流效应,正向电子漂移速度条件下,上行等离子线探测,会过高估计场向电流;负向电子漂移速度条件下,上行等离子线探测会过低估计场向电流.对上下行等离子线同时探测情况,忽略热流效应同样会过高估计场向电流. | 徐彬 吴健 Cesar La Hoz 吴振森 车海琴 薛昆 | 2009 | 空间科学学报2009，29，6： | 2 |
| 6 | Sinus bradycardia as a predictor of right coronary artery occlusion in patients with inferior myocardial infarction显示文摘 | Serrano CV Bortolotm LA Cesar LA | 1999 | Int J Cardiol1999，68，1： | 1 |
| 7 | Slow coronary run-off in patients with angina pectoris : clinical significance and Thallium-201 scintigraphic study显示文摘 | Cesar LA Ramires JA Serrano CV | 1996 | Braz J reed Biol Res1996，29，6： | 1 |
| 8 | The baseline serum value of α-amylase is a significant predictor of distance running performance显示文摘 | Giuseppe Lippi Gian Luca Salvagno Elisa Danese Cantor Tarperi Antonio La Torre Gian Cesare Guidi Federico Schena | 2015 | Clinical Chemistry and Laboratory Medicine (CCLM)2015，，3： | 1 |
| 9 | Syphilitic aortitis causing critical obstruction of coronary ostia显示文摘 | Vianna CB Shiozaki AA Cesar LA | 2009 | Eur Heart J2009，30，： | 1 |
| 10 | Comparative study between verapamil and adenosine triphosphate in the treatment of paroxysmal supraventrieular taehycardia 显示文摘 | Ferreira JF Pamplona D Cesar LA | 1996 | Arq Bras Cardiol1996，66，2： | 1 |
| 11 | Guideline for stable coronary artery disease显示文摘 | Cesar LA Ferreira JF Armaganijan D | 2014 | Arq Bras Cardiol2014，103，： | 1 |
| 12 | Review of the El Soplao Amber Outcrop,Early Cretaceous of Cantabria,Spain显示文摘El Soplao 露头,最近在北西班牙(Cantabria ) 发现的早白垩纪琥珀存款,被显示了是有到目前为止在西班牙被发现了的节肢动物包括的琥珀的最大的地点。为琥珀,孢粉学, taphonomy 和那些以前出版了的节肢动物 bioinclusions 补充的 biogeochemistry 此处提供的相关数据。数据的这个集合为 El Soplao 沉积物的琥珀建议至少二植物的来源。? rst (类型 A 琥珀) 强烈支持与 Cheirolepidiaceae 有关的来源,并且第二(类型 B 琥珀) 显示出非特定的针叶树 biomarkers。有 Frenelopsis 的琥珀离开的类型(Cheirolepidiaceae ) 的分子的作文的比较强烈建议一种生物化学的亲密关系和普通植物的起源。初步的 palynologlcal 研究显示地区性的高分类的差异,主要蕨类植物孢子和裸子植物花粉谷物。根据初步的 palynologlcal 数据,这个区域由在副热带的气候下面使适应一个旱季的针叶树森林被住在。在一样的床上与琥珀联系的丰富的 charcoalified 木头是很可能加植物表皮支持了树脂生产和崽,和琥珀的随后的大累积的集中的侵蚀的 paleofires 的证据。另外,第一次在石块记录,在琥珀的 bioinclusions 被报导的 charcoalified 植物纤维。另外的相关 taphonomic 数据在两个都显示长暴露在上的一些琥珀片的表面上是 serpulids 和 bryozoans 的非凡的存在海洋或略有盐味水并且琥珀的一个混合集合。最后,昆虫 bioinclusions 的新调查结果,他们中的一些在石块记录不平常或显示出显著改编,被报导。在结论,为 El Soplao 琥珀露头的起源的一种记录情形被提供。 | María NAJARRO Enrique PENALVER Ricardo PEREZ-DE LA FUENTE Jaime ORTEGA-BLANCO Cesar MENOR-SALVAN Eduardo BARRON Carmen SORIANO Idoia ROSALES Rafael LOPEZ DEL VALLE Francisco VELASCO Fernando TORNOS Véronique DAVIERO-GOMEZ Bernard GOMEZ Xavier DELCLOS | 2010 | Acta Geologica Sinica(English Edition)2010，84，4： | 1 |
| 13 | ECL cell tumor and poorly differentiated endocrine carcinoma of the stomach: Prognostic evaluation by pathological analysis显示文摘 | Guido Rindi Cinzia Azzoni Stefano La Rosa Catherine Klersy Donatella Paolotti Sigrid Rappel Manfred Stolte Carlo Capella Cesare Bordi Enrico Solcia | 1999 | Gastroenterology1999，，3： | 1 |
| 14 | Sinus bradycardia as a predictor of right cornary artery occlusion in patients with inferior myocardial infarction显示文摘 | Serrano CV Bortolotto LA Cesar LA | 1999 | Int J Cardial1999，68，1： | 1 |
| 15 | Transportation of heavy and extra-heavy crude oil by pipeline: a review显示文摘 | Martinez-Palou R Maria de Lourdes M Beatriz Z-R Elizabeth M-J Cesar B-H Juan de la Cruz C-L Jorge A | 2011 | J Pet Sci Eng2011，30，75： | 1 |
| 16 | Sinus bradycardia as a predictor of right coronary artery occlusion in patients with inferior myocardial infarction显示文摘 | Serrano CV Bortolotto LA Cesar LA | 1999 | Int J Cardiol1999，68，1： | 1 |
| 17 | Detection and subtyping of Actinobacillus stains by PCR-TFLP analysis of the tbpA and tbpB gene显示文摘 | Victor A de la Puente-Redondo Noemi Garcia Cesar B | 2000 | Res Microbiol2000，151，： | 1 |
| 18 | ECL cell tumor and poorly differentiated endocrine carcinoma of the stomach: Prognostic evaluation by pathological analysis显示文摘 | Guido Rindi Cinzia Azzoni Stefano La Rosa Catherine Klersy Donatella Paolotti Sigrid Rappel Manfred Stolte Carlo Capella Cesare Bordi Enrico Solcia | 1999 | Gastroenterology1999，，3： | 1 |
| 19 | Detection and subtyping of Actinobacillus pleuropneu- moniae stains by PCR-RFLP analysis of the tbpA and tbpB genes 显示文摘 | VICTOR A de la Puente-Redondo NOEMI Garcia CESAR B | 2000 | Res Microbiol2000，151，8： | 1 |
| 20 | Strain-induced spatially indirect exciton recombination in zinc-blende/wurtzite CdS heterostructures显示文摘Strain engineering provides an effective mean of tuning the fundamental properties of semiconductors for electric and optoelectronic applications. Here we report on how the applied strain changes the emission properties of hetero- structures consisting of different crystalline phases in the same CdS nanobelts. The strained portion was found to produce an additional emission peak on the low-energy side that was blueshifted with increasing strain. Furthermore, the additional emission peak obeyed the Varshni equation with temperature and exhibited the band-filling effect at high excitation power. This new emission peak may be attributed to spatially indirect exciton recombination between different crystalline phases of CdS. First-principles calculations were performed based on the spatially indirect exciton recombination, and the calculated and experimental results agreed with one another. Strain proved to be capable of enhancing the anti-Stokes emission, suggesting that the efficiency of laser cooling may be improved by strain engineering. | Dehui Li Yang Liu Maria de la Mata Cesar Magen Jordi Arbiol Yuanping Feng Qihua Xiong | 2015 | Nano Research2015，8，9： | 1 |
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