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| 1 | OPTICAL PROPERTIES OF GeO_2 AND Ge NANOCRYSTALS显示文摘he co m pound m aterial of n m size particles Ge O2 Si O2 w as synthesied through hydrolysis of Si( O C2 H4) and Ge Cl4 . A heat treatm ent w as carried out for the sa m ples at 100 ~1200 ℃in air . Its optical property w as deter mined by U V Vis spectur m . We have found that theabsorption edge of spectru m shifted progressively to longer w avelengths . The quantu m size ef fect of nanocrystals appears because crystals gro w and energy of optical band gap reduces d ueto the influence of te m perature . By the analysis of X ray diffraction w e have observed theprocess in w hich the structure of particles changed fro m disorder into order . | Y.H.Zhou 1) ,Y.Y.Feng 2) and H.Y.Lu 2) 1)Department of Physics Nanjing Normal University, Nanjing 210097,China 2)Physics and Ch寁O P T I C A L P R O P E R T I E S O F Ge O2 A N D Ge N A N O C R Y S T A L S Y. H. Zhou1) , Y. Y. Feng2) | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，5： | 22 |
| 2 | Protective actions of salvianolic acid A on hepatocyte injured by peroxidation in vitro显示文摘INTRODUCTION Salvianolic radix,one of the most commonly usedtraditional Chinese herbs,was widely studied aboutits actions against liver injury and fibrosis,and wasone of the focuses of recent research.Salvianolic acid-A(SA-A)was an aqueous solublecomponent of Salvianolic radix.In our | Hu YY Liu CH Wang RP Liu C Liu P Zhu DY | 2000 | World Journal of Gastroenterology2000，6，3： | 15 |
| 3 | Effects of partial portal vein arterialization on the hilar bile duct in a rat model显示文摘BACKGROUND: Liver revascularization is frequently required during the enlarged radical operation for hilar cholangio carcinoma involving the hepatic artery. Researchers have carried out a number of experiments applying partial porta vein arterialization (PVA) in clinical practice. In this study we aimed to establish a theoretical basis for clinical application o partial PVA and to investigate the effects of partial PVA on ra hilar bile duct and hepatic functions. METHODS: Thirty rats were randomly and equally assigned into 3 groups: control (group A), hepatic artery ligation+bile duct recanalization (group B), and partial PVA+bile duc recanalization (group C). Proliferation and apoptosis o rat hilar bile duct epithelial cells, arteriolar counts of the peribiliary plexus (PBP) of the bile duct wall, changes in serum biochemistry, and pathologic changes in the bile duc were assessed 1 month after operation. RESULTS: The proliferation of hilar bile duct epithelial cells in group B was greater than in groups A and C (P<0.01). No apoptotic hilar bile duct epithelial cells were detected in any of the groups. The PBP arteriolar counts of the hilar bile duc wall were similar in groups A and C (P>0.05), but the coun was lower in group B than in group A (P<0.01). No statistically significant differences in alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and albumin were found in the 3 groups. The gamma-glutamyltransferase value was higher in group B than in groups A and C (P<0.01) The hepatic tissues of groups A and C showed no significan abnormality. Chronic inflammatory changes in the hilar bile duct walls were observed only in group B. CONCLUSION: Partial PVA can restore the arterial blood supply of the hilar bile duct and significantly extenuate the injury to hilar bile duct epithelial cells resulting from hepatic artery ligation. | Shao-Hua Guo, Chong-Hui Li,Yong-Liang Chen, Jian-Ning Song,Ai-Qun Zhang and Cheng Zhou Department of Hepatobiliary Surgery (Guo SH, Li CH, Chen YL, Song JN, Zhang AQ and Zhou C) and Department of Surgical Oncology (Guo SH), General Hospital of PLA, Beijing 100853, China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，5： | 8 |
| 4 | 巨噬细胞中缺氧诱导因子1α表达促进动脉粥样硬化的发展显示文摘粥样硬化病变包含缺氧区域,但缺氧病理生理的重要性未知。缺氧诱导因子1a(hypoxia-induciblefactor-1α,HIF-1α)是细胞对低氧反应的关键转录因子。研究人员对HIF-1α在巨噬细胞促进小鼠动脉粥样硬化的生物学效应方面进行调查和验证。 | 刘莉 叶鹏 Aarup A Pedersen TX Junker N Christoffersen C Bartels ED Madsen M Nielsen CH Nielsen LB | 2016 | 中华高血压杂志2016，24，9： | 3 |
| 5 | Early dynamic transcriptomic changes during preoperative radiotherapy in patients with rectal cancer: A feasibility study显示文摘AIM: To develop novel biomarkers of rectal radiotherapy, we measured gene expression profiles on biopsies taken before and during preoperative radiotherapy. METHODS: Six patients presenting with a locally advanced rectal cancer (T>T2, N0/Nx, M0) eligible for preoperative radiotherapy (45 Gy in 25 fractions) were selected in a pilot study. Six tumor and 3 normal tissues biopsies were taken before and during radiotherapy,after a dose of 7.2 Gy at a median time of 1 h following irradiation (0:27-2:12). Tumor or normal tissue purity was assessed by a pathologist prior to RNA extraction. Mean RNA content was 23 μg/biopsy (14-37) before radiotherapy and 22.7 μg/biopsy (12-35) during radiotherapy. After RNA amplification, biopsies were analysed with 54K HG-U133A Plus 2.0 Affymetrix expression micro-arrays. Data were normalized according to MAS5 algorithm. A gene expression ratio was calculated as: (gene expression during radiotherapy-gene expression before radiotherapy)/gene expression before radiotherapy. Were selected genes that showed a ratio higher than ± 0.5 in all 6 patients. RESULTS: Microarray analysis showed that preoperative radiotherapy significantly up-regulated 31 genes and down-regulated 6 genes. According to the Gene Ontology project classification, these genes are involved in protein metabolism (ADAMDEC1 ; AKAP7 ; CAPN5 ; CLIC5 ; CPE ; CREB3L1 ; NEDD4L ; RAB27A), ion transport (AKAP7 ; ATP2A3 ; CCL28 ; CLIC5 ; F2RL2 ; NEDD4L ; SLC6A8), transcription (AKAP7 ; CREB3L1 ; ISX ; PAB-PC1L ; TXNIP), signal transduction (CAPN5 ; F2RL2 ; RA- B27A ; TNFRSF11A), cell adhesion (ADAMDEC1 ; PXDN ; SPON1 ; S100A2), immune response (CCL28 ; PXDN ; TNFRSF11A) and apoptosis (ITM2C ; PDCD4 ; PVT1). Up-regulation of 3 genes (CCL28 ; CLIC5 ; PDCD4) was detected by 2 different probes and up-regulation of 2 genes (RAB27A ; TXNIP) by 3 probes. CONCLUSION: Micro-arrays can efficiently assess early transcriptomic changes during preoperative radiotherapy for rectal cancer, and may help better understand tumor radioresistance. | Stephane Supiot Wilfried Gouraud Loc Campion Pascal Jezéquel Bruno Buecher Josiane Charrier Marie-Francoise Heymann Marc-Andre Mahé Emmanuel Rio Michel Chérel | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 6 | 越南胡志明市及周边地区大学汉语教学情况调查与对策研究显示文摘本文采用实地考察、数据统计分析等方法对胡志明市及周边地区有汉语教学的5所大学的具体情况进行了调查,调查总人数为364人。结果显示:目前越南大学汉语培养的类型主要有汉语语言专业与非汉语语言专业两类,招生条件日趋灵活,招生数量呈逐年上升的趋势;学生方面,汉语学习的动机主要是为工作服务,学习态度与策略需要改善与协助;教师方面,博士学位教师及外籍教师资源少,有的学校甚至没有;教材方面,由于一些客观原因未能及时更新,教材及参考书籍缺乏。针对目前的汉语教学现状,本文提出以下对策:组织丰富、有效的活动,以帮助学生改善学习态度和策略;通过更多的渠道营造语言环境;越南本土教师积极参加编写具有针对性、统一性的教材;携手创办汉语书架,以丰富汉语参考资料。 | 王玲娟 黄美英 chí cám mùi | 2017 | 重庆师范大学学报(哲学社会科学版)2017，0，1： | 2 |
| 7 | Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture显示文摘 | Pan W Quarles LD Song LH Yu YH Jiao C Tang HB Jiang CH Deng HW Li YJ Zhou HH Xiao ZS | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 8 | Semi-wild wheat from Xi zang(Tibet)显示文摘 | Shao Q Q Li Ch S Basang C R | 1980 | Acta Genet Sin1980，7，2： | 1 |
| 9 | Back to the future:testing in disseminated intravascular coagulation显示文摘 | Toh CH Downey C | 2005 | Blood Coagulation Fibrinolysis2005，16，8： | 1 |
| 10 | MicroRNA miR-326 regulates Th-17 differentiation and is associated with the pathogenesis of multiple sclerosis 显示文摘 | Du CH Liu C Kang JK | 2009 | Nature Immunology2009，10，： | 1 |
| 11 | Proteinuria as a modifiable risk factor for the progression of nondiabetic renal diseases显示文摘 | Jafar T H Stark P C Schm id CH etal | 2001 | Kidney Int2001，60，3： | 1 |
| 12 | Real-time imaging of trapping and ureasedependent transmigration of Cryptococcus neoformans in mouse brain显示文摘 | Shi M Li SS Zheng C Jones GJ Kim KS Zhou H Kubes P Mody CH | 2010 | J Clin Invest2010，120，5： | 1 |
| 13 | Protection of mouse photoreceptors by survival factors in retinal degeneration 显示文摘 | Lavail MM Yasumura D Matthes MT Lau-Villacorta C Unoki K Sung CH | 1998 | Invest Ophthalmol Vis Sci1998，39，3： | 1 |
| 14 | Protection of mouse photoreceptors by survival factors in retinal degenerations 显示文摘 | LaVail MM Yasumura D Matthes MT Lau-Villacorta C Unoki K Sung CH Steinberg RH | 1998 | Invest Ophthalmol Vis Sci1998，39，3： | 1 |
| 15 | Trans-fatty acids intake and risk of myocardial infarction显示文摘 | A Ascherio CH Hennekens JE Buring C Master | 1994 | Circulation1994，89，： | 1 |
| 16 | A novel drought-inducible gene,A TAF1,encodes a NAC family protein that negatively regulates the expression of stress-responsive genes in Arabidopsis显示文摘 | LU P L CH EN N Z AN R SU Z QI B S REN F CHEN J WANG X C | 2007 | Plant Molecular Biology2007，63，2： | 1 |
| 17 | A Cellular MicroRNA Mediates Antiviral Defense in Human Cells显示文摘 | Lecellier CH Dunoyer P Arar K Lehamnn-Che J Eyquem S Himber C | 2005 | Science2005，308，4： | 1 |
| 18 | Hedgehog signaling is essential for maintenance of cancer stem cells in myeloid leukaemia显示文摘 | ZHAO C CHEN A JAMIESON CH | 2009 | Nature2009，458，7239： | 1 |
| 19 | Cytotoxic activity of xanthatin and the crude extracts of Xanthium strumarium显示文摘 | Roussakls CH Chinoul Vavas C | 1994 | Planta Med1994，60，： | 1 |
| 20 | Effects of chronic insomnia and use of benzodiazepines on daytime performance in older adults显示文摘 | Vignola A Lamoureux C Bastien CH | 2000 | Gerontol B Psychol Sci Soc Sci2000，55，： | 1 |
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