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| 1 | Response to endoscopic therapy for biliary anastomotic strictures in deceased versus living donor liver transplantation显示文摘BACKGROUND:Endoscopic therapy has been successful in the management of biliary complications after both deceased donor liver transplantation(DDLT) and living donor liver transplantation(LDLT).LDLT is thought to be associated with higher rates of biliary complications,but there are few studies comparing the success of endoscopic management of anastomotic strictures between the two groups.This study aims to compare our experience in the endoscopic management of anastomotic strictures in DDLT versus LDLT.METHODS:This is a retrospective database review of all liver transplant patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) after liver transplantation.The frequency of anastomotic stricture and the time to develop and to resolve anastomotic stricture were compared between DDLT and LDLT.The response of anastomotic stricture to endoscopic therapy was also analyzed.RESULTS:A total of 362 patients underwent liver transplantation between 2003 and 2011,with 125 requiring ERCP to manage biliary complications.Thirty-three(9.9%) cases of DDLT and 8(27.6%) of LDLT(P=0.01) were found to have anastomotic stricture.When comparing DDLT and LDLT,there was no difference in the mean time to the development of anastomotic strictures(98±17 vs 172±65 days,P=0.11),likelihood of response to ERCP [22(66.7%) vs 6(75.0%),P=0.69],mean time to the resolution of anastomotic strictures(268±77 vs 125±37 days,P=0.34),and the number of ERCPs required to achieve resolution(3.9±0.4 vs 4.7±0.9,P=0.38).CONCLUSIONS:Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation.Anastomotic strictures occur more frequently in LDLT compared with DDLT,with equivalent endoscopic treatment response and outcomes for both groups. | Calvin HY Chan Fergal Donnellan Michael F Byrne Alan Coss Mazhar Haque Holly Wiesenger Charles H Scudamore Urs P Steinbrecher Alan A Weiss Eric M Yoshida | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 7 |
| 2 | Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes - Association analyses in 9,518 subjects显示文摘 | Owen, KR Groves, CJ Hanson, RL Knowler, WC Shuldiner, AR Elbein, SC Mitchell, BD Froguel,P Ng, MCY Chan, JC Jia, WP Deloukas, P Hitman, GA Walker, M Frayling, TM Hattersley, AT Zeggini, E McCarthy, MI | 2007 | 中国生物学文摘2007，21，11： | 2 |
| 3 | The 40-50 day oscillation and El Nino/Southern Oscillation:A new perspective显示文摘 | Lau K M Chan P H | 1986 | Bull Amer Meteor Soc1986，67，5： | 2 |
| 4 | Framework of Success Criteria for Design Build Projects 显示文摘 | A P C Chan D Scott E W M Lam | 2002 | Journal of Management in Engineering2002，18，3： | 1 |
| 5 | A multicenter trial of photorefractive keratectomy for residual myopia after previous ocular surgery显示文摘 | Maloney RK chan WK Steinert R Hersh P O' Connell M | 1995 | Ophthalmology1995，102，7： | 1 |
| 6 | Cytotoxic Acylated Triterpene Saponins from the husks of Xanthoceras sorbifolia显示文摘 | Chan P K Zhao M Che C T | 2008 | J Nat Prod2008，71，： | 1 |
| 7 | Comparison of the stimulatory sffects of ovine,porcine and human follicle-stimulating hormone and of ovine and human luteinizing hormone on the accumulation of cyclic AMP by porcine granulosa cells显示文摘 | Lindsay A M Channing C P | 1979 | Journal of Endocrinology1979，80，： | 1 |
| 8 | A prospective randomized study of chemotherapy adjunctive to definitive radiotherapy in advanced nasopharyngeal carcinoma显示文摘 | Chan A T Teo P M Leung T W | 1995 | Int J Radiat Oncol Biol Phys1995，33，3： | 1 |
| 9 | Reversal of obesity bytargeted ablation of adipose tissue显示文摘 | Kolonin M G Saha P K Chan L | 2004 | Nat Med2004，10，6： | 1 |
| 10 | A PhysiologicallyBased Pharmacokinetic Model for Endosulfan in the MaleSprague-Dawley Rats显示文摘 | Chan M P Morisawa S Nakayama A | 2006 | Environmental Toxicology2006，21，5： | 1 |
| 11 | Temporal and spatial trends of mercury in fish collected in the English-Wabigoon river system in Ontario, Canada显示文摘 | Kinghorn A Solomon P Chan H M | 2007 | Science of the Total Environment2007，372，2： | 1 |
| 12 | The effect of excimer laser surface treatment on the pitting corrosion fatigue behaviour of alnminium alloy 7075 显示文摘 | Chan C P Yue T M Man H C | 2003 | Journal of Materials Science2003，15，12： | 1 |
| 13 | Fracture Energy of Weakly Reinforced Concrete Beams显示文摘 | Azad A Mirza M Chan P | | 0，，01： | 1 |
| 14 | Cloning of a cDNA encoding a pu- tative molt-inhibiting hormone from the eyestalk of the sand shrimp Metapenaeus ensis 显示文摘 | Gu P L Chan S M | 1998 | Mol Marine Bio- tech1998，7，3： | 1 |
| 15 | Temporal and spatial trends of mercury in fish collected in the English-Wabigoon river system in Ontario, Canada 显示文摘 | Kinghorn A Solomon P Chan H M | 2007 | Science of the Total Environment2007，372，23： | 1 |
| 16 | The rode of chemotherapy in the management of nasopharyngea carcinomal显示文摘 | Chan A T C Teo P M Leung T W | 1998 | Cancer1998，82，6： | 1 |
| 17 | Presenilin mutations and calcium signaling defects in the nervous and immune systems显示文摘 | Mattson M P Chan S L Camandola S | 2001 | Bioessays2001，23，8： | 1 |
| 18 | Nanocrystal targeting in vivo显示文摘 | Akerman M E Chan W C W Laakkonen P | 2002 | Proceedings of the Na- tional Academy of Sciences of the United States of Amer- ica2002，99，12： | 1 |
| 19 | High prevalence of human papillomavirus type 58 in Chinese women with cervical cancer and precancerous lesions显示文摘 | Chan P K Li W H Chan M Y | 1999 | J Med Viral1999，59，2： | 1 |
| 20 | Aspects of the 40-50 day oscillation during the northern summer as inferred from outgoing longwave radiation 显示文摘 | Lau K M Chan P | 1986 | Monthly Weather Review1986，114，7： | 1 |
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