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| 1 | 膳食中钠(盐)与血压的关系及其他膳食因素可能的调节作用显示文摘现有资料表明,膳食钠(盐)与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究(international study on macro/micronutrients and blood pressure,INTERMAP)结果显示,在控制多种非膳食因素情况下,年龄40~59岁的男性和女性4680人(中国、日本、英国和美国的17个人口样本)的血压与24h尿钠排泄和尿钠/钾直接相关。 | 刘莉 叶鹏 Stamler J Chan Q Daviglus ML Dyer AR Van Horn L Garside DB Miura K Wu Y Ueshima H Zhao L Elliott P INTERMAP Research Group | 2018 | 中华高血压杂志2018，26，4： | 8 |
| 2 | Inflammatory bowel disease in Asia: A systematic review显示文摘 | Lani Prideaux Michael A Kamm Peter P De Cruz Francis K L Chan Siew C Ng | 2012 | Journal of Gastroenterology and Hepatology2012，，8： | 5 |
| 3 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010，7，3： | 3 |
| 4 | Oocyte maturation inhibition activity in porcine granulose cells 显示文摘 | Centola G Anderson L Channing C P | 1981 | Gamete Res1981，4，： | 1 |
| 5 | Reversal of obesity bytargeted ablation of adipose tissue显示文摘 | Kolonin M G Saha P K Chan L | 2004 | Nat Med2004，10，6： | 1 |
| 6 | Supplementation-time dependence of growth factors in promoting tendon healing显示文摘 | Chan B P Fu S C Qin L | 2006 | Clin Orthop Relat Res2006，448，1： | 1 |
| 7 | Early and sustained survival benefit associated with statin therapy at the time of percutaneous coronary intervention显示文摘 | Chan A W Bhatt D L Chew D P | | 0，，： | 1 |
| 8 | On the runup of long waves on a plane beach显示文摘 | CHAN I C LIU P L F | 2012 | Journal of Geophysical Research2012，117，8： | 1 |
| 9 | Cloning of a cDNA encoding a pu- tative molt-inhibiting hormone from the eyestalk of the sand shrimp Metapenaeus ensis 显示文摘 | Gu P L Chan S M | 1998 | Mol Marine Bio- tech1998，7，3： | 1 |
| 10 | Strapdown INS error model for muhiposition alignment 显示文摘 | DOHYOUNG C JANG G L CHAN G P | 1996 | IEEE Transactions on Aerospace and Electronic Systems1996，32，4： | 1 |
| 11 | Vibration and Deflection Characteristics of Semi Rigid Jointed Frames 显示文摘 | Peter P T C Chan S L | 1997 | Engineering Structures1997，19，10： | 1 |
| 12 | Microstructure and current-voltage characteristics of ZnO-V2O5-MnO2 varistor system显示文摘 | Hng H H Chan P L | 2003 | Ceramic international2003，，12： | 1 |
| 13 | Presenilin mutations and calcium signaling defects in the nervous and immune systems显示文摘 | Mattson M P Chan S L Camandola S | 2001 | Bioessays2001，23，8： | 1 |
| 14 | Undergraduate Medical Education:Comparison of Problem-based Learning and Conventional Teaching显示文摘 | Nandi P L Chan J N F Chan C P K | 2000 | HKMJ2000，6，3： | 1 |
| 15 | Atomic force microscopy study of microbiologically influenced corrosion of mild steel显示文摘 | Xu L C Fang H H P Chan K Y | 1999 | Electrochemistry Society1999，146，12： | 1 |
| 16 | Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B显示文摘 | Wong G L Wong V W Choi P C Chan A W Chim A M Yiu K K | 2009 | Gut2009，58，： | 1 |
| 17 | Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma显示文摘 | Chan J L Tang K C Patel A P | 2006 | Blood2006，107，： | 1 |
| 18 | Neuroprotective and neurorestorative signal transduction mechanisms in brain aging:modification by genes,diet and behavior显示文摘 | MATTSON M P DUAN W CHAN S L | 2002 | Neurobiol Aging2002，23，5： | 1 |
| 19 | Imaging of peripheral PNET:common and uncommon locations显示文摘 | Khong P L Chan G C Shek T W H | 2002 | Clin Radiol2002，57，4： | 1 |
| 20 | Com-pact multiple-valued multiplexers using negative differen-tial resistance devices 显示文摘 | CHAN H L MOHAN S MAZUMDER P | 1996 | IEEE Journal of Sold-StateCircuits1996，31，8： | 1 |
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