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| 1 | Association of time to prostate-specific antigen nadir and logarithm of prostate-specific antigen velocity after progression in metastatic prostate cancer with prior primary androgen deprivation therapy显示文摘我们与优先的主要雄激素剥夺治疗(ADT ) 在变形前列腺癌症在前进木头(PSAVAP ) 以后调查了前列腺特定的抗原天底(TTPN ) 和前列腺特定的抗原速度的对数的时间的协会。从 2000 ~ 2009 与主要 ADT 对待的所有变形前列腺癌症病人被考察。开发了疾病前进的病人在随后的分析被包括。病人们根据他们的 TTPN 被分成三个组:< 的 TTPN; 3 个月, 3-17 月,和 > 17 个月。我们用 Mann-Whitney U-test 和 Kruskal-Wallis 测试比较了在不同 TTPN 组之间的木头(PSAVAP ) 。木头(PSAVAP ) 上的进一步多重的线性回归分析被执行为使因素惊讶的另外的潜力调整。在与主要 ADT 被对待的 419 个病人之中, 306 个病人与 28 个月的中部的后续开发了疾病前进。更长的 TTPN 与更低的木头(PSAVAP ) 被联系(P = 0.008 ) 在所有亚群分析以内(< 的 TTPN; 3 对 3-17 月, P = 0.020;3-17 对 > 的 TTPN; 17 个月, P = 0.009;并且 < 的 TTPN; 3 对 > 17 个月, P = 0.001 ) 。在多重线性回归分析之上,基线 PSA (回归系数 0.001 , P = 0.045 ), PSA 天底(回归系数 0.002 , P = 0.040 ),并且 TTPN (回归系数 − ; 0.030 , P = 0.001 )是显著地与木头( PSAVAP )被联系的三个因素。在结论,更长的 TTPN 在跟随主要 ADT 的变形前列腺癌症病人与更低的木头(PSAVAP ) 被联系。在 3 个月和 17 个月的 TTPN cut-offs 看起来在预言木头(PSAVAP ) 有预示的意义。TTPN 可以在与疾病前进在病人决定治疗策略用作好预示的指示物。 | Jeremy YC Teoh James HL Tsu Steffi KK Yuen Peter KF Chiu Samson YS Chan Ka-Wing Wong Kwan-Lun Ho Simon SM Hou Chi-Fai Ng Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 6 |
| 2 | Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome显示文摘Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory support.We aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this disease.Methods Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome Database.Intubation rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( NIVHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital groups.Results Both hospital groups had comparable demographics and clinical profiles, but NIV Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid commencement.Compared to IMV Hospitals (451 patients), NIV Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid rescue.There were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive ventilation.Conclusion Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality. | Loretta YC Yam Alfred YF Chan Thomas MT Cheung Eva LH Tsui Jane CK Chan Vivian CW Wong | 2005 | Chinese Medical Journal2005，，17： | 3 |
| 3 | Spinal aneurysmal bone cyst causing acute cord compression without vertebral collapse:CT and MRI findings显示文摘 | Chan MS Wong YC Yuen MK | 2002 | Pediatr Radiol2002，32，8： | 2 |
| 4 | Comparative analysis of NS3 sequences of temporally separated dengue virus strains isohted from southeast Asia显示文摘 | Chow VTK Seah CL Chan YC | 1994 | Intervirology1994，37，： | 1 |
| 5 | MR imaging of bone marrow edema and joint effusion in patients with osteonecrosis of the femoral head : relationship to pain 显示文摘 | Huang GS Chan WP Chang YC | 2003 | ARJ Am J Roentgenol2003，181，： | 1 |
| 6 | Radiation dose reduction in pediatric cranial CT显示文摘 | Chan CY Wang YC Chau LE | 1999 | Pediatr Radiol1999，29，： | 1 |
| 7 | Electricity use characteristics of purpose-bulh office buildings in subtropical climates 显示文摘 | Lain C Joseph Chan YC Ricky Tsang CL | 2004 | Energy Conversion and Management2004，45，6： | 1 |
| 8 | The positive correlation between cord serum retinol-binding protein 4 concentrations and fetal growth显示文摘 | Chan TF Tsai YC Wu CH | | 0，，02： | 1 |
| 9 | The effectiveness of serum alpha- fetoprotein level in anti-HCV positive patients for screening hepa- tocellular carcinoma 显示文摘 | Peng YC Chan CS Chen GH | 1999 | Hepatogastroenterology1999，46，30： | 1 |
| 10 | Extracoronal resilient attachments in distal extension removable partial dentures 显示文摘 | Ku YC Shen YF Chan CP | 2000 | Quintessence lnt2000，31，5： | 1 |
| 11 | Therapeutically relevant concentrations of raloxifene dilate pressurized rat resistance arteries via calcium-dependent endothelial nitric oxide synthase activation显示文摘 | Chan YC Leung FP Wong WT Tian XY Yung LM Lau CW Tsang SY Yao X Chen ZY Huang Y | | 0，，： | 1 |
| 12 | Human heart-type fatty acid- binding protein for on-site diagnosis of early acute myocardial in- farction显示文摘 | Liao J Chan CP Cheung YC | 2009 | Int J Cardiol2009，133，3： | 1 |
| 13 | Nail infestation by Liposcelis bostrychophila Badonnel 显示文摘 | Lin YC Chan ML Ko CW | 2004 | Clin Exp Dermatol2004，29，6： | 1 |
| 14 | miR-210:The master hypoxamir显示文摘 | Chan YC Banerjee J Choi SY | 2012 | Microcirculation2012，19，： | 1 |
| 15 | Human heart-type fatty acid-binding protein for on site diagnosis of early acute myocar dial infarction显示文摘 | Liao J Chan CP Cheung YC | 2009 | Int J Cardiol2009，133，3： | 1 |
| 16 | Experimental microarterial grafts: freeze-dried allografts versus autografts显示文摘 | SO YC Chan CW | 1983 | Br J Plast Surg1983，36，： | 1 |
| 17 | Spinal aneurysmal bone cyst causing acute cord compression without vertebral collapse:CT and MRI findings显示文摘 | Chan MS Wong YC | 2002 | Pediatr Radiol2002，32，： | 1 |
| 18 | Extracoronal resilient attachments indistal-extension removable partial dentures显示文摘 | Ku YC Shen YF Chan CP | 2003 | QIIintesence hat2003，31，5： | 1 |
| 19 | The effects of eradication of Helicobacter pylori on the recurrence of duodenal ulcers in patients with cirrhosis显示文摘 | Lo GH Yu HC Chan YC | | 0，，03： | 1 |
| 20 | Acute pancreatitis : animal models and recent ad- vances in basic research显示文摘 | Chan YC Leung PS | 2007 | Pancreas2007，34，1： | 1 |
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