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| 1 | Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development显示文摘cytosine 的 Methylation 是与基因压抑联系的 DNA 修正。最近,新奇 cytosine 修正, 5-hydroxymethylcytosine (5-hmC ) 被发现了。这里,我们在哺乳动物的开发期间并且在细胞的系统检验 5-hmC 分发,并且证明 5-hmC 的发展动力学与 5-methylcytosine (5-mC ) 的那些不同;特别地 5-hmC 与成年纸巾相比在胚胎的上下文被充实。一个可检测的 5-hmC 信号在在父亲的染色体受到 5-mC 的染色体宽的 hydroxylation 的地方,在接合子阶段开始的培植前开发出现,它精确在父亲的前核与 5-mC 信号的损失与一致。5-hmC 的层次与在老鼠的表示 nestin 房间人口在在胚囊,和修正 colocalises 的内部房间团的房间高培植以后的胚胎。比作另外的成年哺乳动物的机关, 5-hmC 强烈在骨头髓和大脑被充实, 5-hmC 内容在那里高是 neuronal 祖先和 mitotic 以后神经原的一个特征。我们证明 5-hmC 的那高水平是在老鼠和人的胚胎的干细胞(转换字符) 的不仅现在并且,在区别期间输以前被报导了,而且在导致的 pluripotent 干细胞的产生期间重现;因此, 5-hmC 丰富与一个 pluripotent 房间状态相关。我们的调查结果建议除了 neuronal 系的房间, genomic 5-hmC 的高水平是胚胎的房间人口和细胞的 pluri 系和多系力量的一个 epigenetic 特征。到我们的知识, 5-hmC 那么代表其丰富是的发现的 DNA 的第一 epigenetic 修正房间类型特定。 | Alexey Ruzov Yanina Tsenkina Andrea Serio Tatiana Dudnakova Judy Fletcher Yu Bai Tatiana Chebotareva Steve Pells Zara Hannoun Gareth Sullivan Siddharthan Chandran David C Hay Mark Bradley Ian Wilmut Paul De Sousa | 2011 | Cell Research2011，21，9： | 4 |
| 2 | ITO deposited by pyrosol for photovoltaic applications显示文摘 | Chebotareva A B Untila G G Kost T N | 2007 | Thin Solid Films2007，515，： | 1 |
| 3 | Crystallization of calcium carbonate in magnetic water in the presence of paramagnetic substances显示文摘 | Goncharuk V V Bagrii V A Chebotareva R D | 2008 | Russian Journal of Applied Chemistry2008，81，12： | 1 |
| 4 | The effect of an alternating electromagnetic field upon early development in roach (ru- tilus rutilus: cyprinidae, cypriniformes)显示文摘 | Chebotareva Y V Izyumov Y G: Krylow V V | 2009 | Journal of Ichthyology2009，49，5： | 1 |
| 5 | Production ofsodium hypochlorite in an electrolyser equipped with a ceramicmembrane显示文摘 | BashtanSY Goncharuk VV Chebotareva RD | 1999 | Desalination1999，126，： | 1 |
| 6 | Produc- tion of sodium hypochlorite in an electrolyser equipped with ace ramic membrane显示文摘 | Bashtan S Y Goncharuk V V Chebotareva R D | 1999 | Desalination1999，126，13： | 1 |
| 7 | Estimation of podocyte dysfunction by nephrinuria severity in proteinuric forms of chronic glomerulonephritis显示文摘 | Chebotareva NV Bobkova IN Kozlovskaia LV | 2011 | Ter Arkh2011，83，6： | 1 |
| 8 | Cloned rats produced by nuclear transfer from adult somatic cells显示文摘 | Chailakhyan T A Vikhlyantseva E F Chebotareva T | 2003 | Dokl Biol Sci2003，388，4： | 1 |
| 9 | Influence of hydrogen bonds on the supramolecular order of Hexa-peri- hexabenzocoronens显示文摘 | Wasserfallen D Fishbach I Chebotareva N | 2005 | Adv Funct Mater2005，15，： | 1 |
| 10 | Large intestine dysbacteriosis and therapy efficacy in patients with respiratory tract tuberculosis in sanatoria显示文摘 | Dugina N N Chebotareva T V Mitrokhin S D | 2004 | Antibiot Khimioter2004，49，4： | 1 |
| 11 | Production of sodium hypochlorite in an electrolyser equipped with a ceramic membrane显示文摘 | S Y Bashtan V V Goncharuk R D Chebotareva V N Belyakov and V M Linkov | | 0，，： | 1 |
| 12 | ITO Deposited by Pyrosol for Photovoltaic Applicatiom显示文摘 | Chebotareva A B Untila G G Kost T N | 2007 | Thin Solid Films2007，515，24： | 1 |
| 13 | Crystallization of calcium carbonate in magnetic water in the presence of paramagnetic substances 显示文摘 | Goncharuk V V Bagrii V A Chebotareva R D | 2008 | Russian Journal of Applied Chemistry2008，81，12： | 1 |
| 14 | Mammalian and malaria parasite cyclase-associated proteins catalyze nucleotide exchange on G-actin through a conserved mechanism显示文摘 | Makkonen M Bertling E Chebotareva NA | 2013 | J Biol Chem2013，288，2： | 1 |
| 15 | Production of sodium hypochlorite in an electrolyser equipped with a ceramic membrane显示文摘 | Bashtan SY Goncharuk W Chebotareva RD | 1999 | Desalination1999，126，13： | 1 |
| 16 | Surface modification of anion-exchange electrodialysis membranes to enhance anti-fouling characteristics显示文摘 | Grebenyuk V D Chebotareva R D Peters S | 1998 | Desalination1998，115，3： | 1 |
| 17 | Crystallization of calcium carbonate in magnetized water in the presence of paramagnetic substances显示文摘 | V. V. Goncharuk V. A. Bagrii R. D. Chebotareva S. Yu. Bashtan A. V. Nanieva | 2009 | Journal of Water Chemistry and Technology2009，，3： | 1 |
| 18 | Effect of conditions of deposition and annealing of indium oxide films doped with fluorine (IFO) on the photovoltaic properties of the IFO/p-Si heterojunction 显示文摘 | Untila G G Kost N T Chebotareva A B | 2008 | Semiconductors2008，42，4： | 1 |
| 19 | Modifications to improve the efficiency of zona-free mouse nuclear transfer显示文摘 | Ribas R Oback B Ritchie W and Chebotareva T | 2006 | Cloning and Stem Cells2006，8，： | 1 |
| 20 | On adaptative changes of rates of oxygen consumption and lipid metabolism in Littorina saxatilis at parasitic invasions 显示文摘 | Arakelova E S Chebotareva M A Zabelinskii S A | 2003 | Journal of Evolutionary Biochemistry and Physiology2003，，39： | 1 |
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