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12篇 您的检索式:作者名="Checquolo"
    题名 作者 年代 出处 被引量
1Notch3:from subtle structural differences to functional diversity显示文摘Bellavia D Checquolo S Campese AF 0,,38:1
2Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis显示文摘Bellavia D Campese AF Checquolo S 0,,:1
3Combined expression of pTalpha and Notch-3 in T cell leukemia identifies the requirement of pre-TCR for leukemogenesis显示文摘Bellavia D Campese AF Checquolo S 2002Proc Natl Acad Sci USA2002,99,6:1
4Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis显示文摘Bellavia D Campese AF Checquolo S 2002Proc Natl Acad Sci USA2002,99,6:1
5Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement ofpreTCR for leukemogenesis显示文摘Bellavia D Campese AF Checquolo S 2002Proc Natl Acad Sci U S A2002,99,6:1
6The molecular basis of notch signaling regulation:a complex simplicity 显示文摘Palermo R Checquolo S Bellavia D 2014Curr Mol Med2014,14,1:1
7Notch3 :from su- btle structural differences to functional diversity显示文摘Bellavia D Checquolo S Campese A F 2008Onco- gene2008,27,38:1
8Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis 显示文摘Bellavia D Campese AF Checquolo S 2002Proc Natl Aead Sci2002,99,6:1
9Notch3: from subtle structural differences to functional diversity 显示文摘Bellavia D Checquolo S Campese AF 2008Oncogene2008,27,38:1
10Combined expression of pTalpha and Notch-3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis显示文摘BELLAVIA D CAMPESE A F CHECQUOLO S 2002Proc Natl Acad Sci USA2002,99,:1
11Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis显示文摘Bellavia D Campese AF Checquolo S 2002Proc Natt Acad Sci U S A2002,99,6:1
12Notch signaling in female cancers: a multifaceted node to overcome drug resistance显示文摘Drug resistance is one of the main challenges in cancer therapy,including in the treatment of female-specific malignancies,which account for more than 60%of cancer cases among women.Therefore,elucidating the underlying molecular mechanisms is an urgent need in gynecological cancers to foster novel therapeutic approaches.Notably,Notch signaling,including either receptors or ligands,has emerged as a promising candidate given its multifaceted role in almost all of the hallmarks of cancer.Concerning the connection between Notch pathway and drug resistance in the afore-mentioned tumor contexts,several studies focused on the Notch-dependent regulation of the cancer stem cell(CSC)subpopulation or the induction of the epithelial-to-mesenchymal transition(EMT),both features implicated in either intrinsic or acquired resistance.Indeed,the present review provides an up-to-date overview of the published results on Notch signaling and EMT-or CSC-driven drug resistance.Moreover,other drug resistance-related mechanisms are examined such as the involvement of the Notch pathway in drug efflux and tumor microenvironment.Collectively,there is a long way to go before every facet will be fully understood;nevertheless,some small pieces are falling neatly into place.Overall,the main aim of this review is to provide strong evidence in support of Notch signaling inhibition as an effective strategy to evade or reverse resistance in female-specific cancers.Maria V.Giuli Angelica Mancusi Eugenia Giuliani Isabella Screpanti Saula Checquolo 2021Cancer Drug Resistance2021,4,4:0
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