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| 1 | Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study显示文摘AIM To study the impact of vaccination critical illness due to H1N1pdm09, we compared the incidence and severity of H1N1pdm09 infection in Canada and France.METHODS We studied two national cohorts that included children with documented H1N1pdm09 infection, admitted to a pediatric intensive care unit(PICU) in Canada and in France between October 1, 2009 and January 31, 2010.RESULTS Vaccination coverage prior to admission to PICUs was higher in Canada than in France(21% vs 2% of children respectively, P < 0.001), and in both countries, vaccination coverage prior to admission of these critically ill patients was substantially lower than in the general pediatric population(P < 0.001). In Canada, 160 children(incidence = 2.6/100000 children) were hospitalized in PICU compared to 125 children(incidence = 1.1/100000) in France(P < 0.001). Mortality rates were similar in Canada and France(4.4% vs 6.5%, P = 0.45, respectively), median invasive mechanical ventilation duration and mean PICU length of stay were shorter in Canada(4 d vs 6 d, P = 0.02 and 5.7 d vs 8.2 d, P = 0.03, respectively). H1N1pdm09 vaccination prior to PICU admission was associated with a decreased risk of requiring invasive mechanical ventilation(OR = 0.30, 95%CI: 0.11-0.83, P = 0.02).CONCLUSION The critical illness due to H1N1pdm09 had a higher incidence in Canada than in France. Critically ill children were less likely to have received vaccination prior to hospitalization in comparison to general population and children vaccinated had lower risk of ventilation. | Olivier Fléchelles Olivier Brissaud Robert Fowler Thierry Ducruet Philippe Jouvet the Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques | 2016 | World Journal of Clinical Pediatrics2016，5，4： | 2 |
| 2 | The nested radiosity model for the distribution of light within plant canopies显示文摘 | CHELLE M A | 1998 | Eeolosical Modelling1998，111，： | 1 |
| 3 | Insights into neural stem cell biology in flies显示文摘 | Egger B Chell J M Brand A | 2008 | Phil Trans R Soe B2008，363，1489： | 1 |
| 4 | The nested radiosity model for the distribution of light within plant canopies显示文摘 | Michael Chelle Bruno Andrieu | 1998 | Ecological Modeling1998，111，： | 1 |
| 5 | An Overview of Object Oriented Simulation显示文摘 | Chell A Robe s Yasser M Dessouky | 1998 | SimuJation1998，70，6： | 1 |
| 6 | Human transforming growth factor - beta complementary DNA sequence and expression in normal and transformed cells显示文摘 | Derynck R Jarrett JA Chell EY | 1985 | Nature1985，6030，： | 1 |
| 7 | A study of entrepreneurship in the restaurant and cafe industry:Exploratory work using the critical incident technique as a methodology显示文摘 | Pittaway L | 1998 | International Journal of Hospitality Management1998，17，1： | 1 |
| 8 | Cerebral monitoring:jugular venous oximetry显示文摘 | Chell RM Cole DJ | 2000 | Anesth Analg2000，90，4： | 1 |
| 9 | An overview of object oriented simulation 显示文摘 | CHELL A R YASSER M D | 2005 | Simulation2005，7，6： | 1 |
| 10 | Abdominal wall abscess presenting 35 years after insertion of an intrauterine contraceptive device显示文摘 | Chell KI Lipscomb GH | 2010 | Obstet Gynecol2010，115，22： | 1 |
| 11 | Design and performance of a permanent- magnet rotary refrigerator显示文摘 | C Zimm A Boeder J Chell | 2006 | International Journal of Refrigeration2006，29，8： | 1 |
| 12 | An Overview of Object-Oriented Simulation显示文摘 | Robers Chell A Dessouky Yasser M | 1998 | Simulation1998，70，6： | 1 |
| 13 | Light interception of contrasting azimuth canopies under square and rectangular plant spatial distributions:Simulations and crop measurements 显示文摘 | Maddonni G A Chelle M Drouet J L | 2001 | Field Crops Research2001，70，1： | 1 |
| 14 | Control of virulence and pathogenicity genes ofRalstonia solanacearum by an elaborate sensory network 显示文摘 | CHELL M A | 2000 | Annu Rev Phytopathol2000，38，9： | 1 |
| 15 | Characterizat ion of the ef- fect s of isoprostanes on platelet aggregation in human whole blood 显示文摘 | Cranshaw JH Evans TW Mit chell JA | 2001 | British J Pharmacol2001，132，8： | 1 |
| 16 | A Study of Entrepreneurship in the Restaurant and Caf6 Industry: Exploratory Story Work Us- ing the Critical Incident Technique as a Methodology 显示文摘 | Chell E Pittacay L | 1998 | International Journal of Hospitality Management1998，17，3： | 1 |
| 17 | Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treat- ment of colorectal cancer显示文摘 | Chell S Kaidi A Williams A C | 2006 | Biochim Biophys Acta2006，1766，1： | 1 |
| 18 | Production and partial characterization of a novel protease from marine Engyodontium album BTMFS10 under solid state fermentation 显示文摘 | CHELL APPAN S JASMIN C BASHEER M | 2006 | Proe Biochem2006，41，4： | 1 |
| 19 | Mediators of PGE2 synthesis and signlling downstream of COX-2 represent potential targets for the prevention /treatment of colorectal cancer 显示文摘 | CHELL S KAIDI A WILLIAMS AC | 2006 | Bioehim Biophys Acta2006，1776，1： | 1 |
| 20 | Design and performance of a permanentmagnet rotary refrigerator显示文摘 | Zimm C Boeder A Chell J Sternberg A Fujita A Fujieda S Fukamichi K | | 0，，： | 1 |
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