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| 1 | Enzymohistochemical study on burn effect on rat intestinal NOS显示文摘INTRODUCTION The blood irrigate flow obstruction,especially thegastrointestinal(GI)ischemia,is the main factorof the damage to the digestive tract caused byserious burns.The effect of GI ischemia on thewhole body is extensive and profound,which notonly causes the increase of intestinal permeabilityand the movement of bacteria and toxin in theintestinal cavity,but releases a large quantity ofinflammatory media.Neuroendocrine element | Wang QG He LY Chen YW Hu SL | 2000 | World Journal of Gastroenterology2000，6，3： | 12 |
| 2 | 小胶质细胞对星形胶质细胞的免疫和神经保护功能的调节作用(英文)显示文摘在中枢神经系统中,小胶质细胞和星形胶质细胞对神经元的发育、功能维持及细胞存活具有重要的作用。但在炎症反应过程中,星形胶质细胞增生的作用及其对神经元的影响目前并不十分清楚。因此,本研究对不同种类的细胞进行培养,给予细菌脂多糖(lipopolysaccharide,LPS)刺激,观察各种细胞的反应。结果显示,星形胶质细胞可以减轻炎症反应的神经元毒性,提示星形胶质细胞增生主要具有神经保护作用。如果去掉上清液中由星形胶质细胞分泌的胶质细胞源性神经营养因子(glial cell line-derived neurotrophic factor,GDNF),这种神经保护作用显著降低。为了研究星形胶质细胞的免疫功能,本研究培养了高浓度的星形胶质细胞,并发现LPS不能诱导肿瘤坏死因子(tumor necrosis factor,TNF)-α及诱导型一氧化氮合酶(inducible nitric oxide synthase,iN OS)/一氧化氮(nitric oxide,NO)(iN OS/NO)释放。但如果在培养的高浓度星形胶质细胞中增加0.5%~1%的小胶质细胞,则可以诱导TNF-α及iN OS/NO的释放。这提示小胶质细胞和星形胶质细胞间的相互作用对于LPS诱导星形胶质细胞释放前炎症因子及GDNF是必须的。我们还发现,小胶质细胞释放的TNF-α可以通过旁分泌作用调节星形胶质细胞的神经保护功能。综上所述,本研究结果提示星形胶质细胞可能不会直接被LPS激活,而是通过与小胶质细胞相互作用被激活,释放神经营养因子,减少因炎症反应激活的小胶质细胞释放的毒性物质对神经元的损害作用。 | Chen SH Oyarzabal EA Sung YF Chu CH Wang Q Chen SL Lu RB Hong JS 唐颖馨 | 2015 | 神经损伤与功能重建2015，10，1： | 9 |
| 3 | REAL-VALUED PERIODIC WAVELETS: CONSTRUCTION ANDRELATION WITH FOURIER SERIES显示文摘1.IntroductionWaveletshaverecentlyreceivedagreatdealofattentioninsuchareasassignalprocessingandimageprocessing([12],[8]).Variousmethodstoconstructwaveletshavebeengiven([14],[13],[9],[7]).Itiswellknownthatinmathematicsandmathematicphysicsmanyperiodicp... | Chen, HL Liang, XZ Peng, SL Xiao, SL | 1999 | Journal of Computational Mathematics1999，17，5： | 3 |
| 4 | THE CHEMICAL STRUCTURE OF CELASTRINE FROM CELASTRUS FLAGELLARIS显示文摘THECHEMICALSTRUCTUREOFCELASTRINEFROMCELASTRUSFLAGELLARIS￥MingAnWANG;MinWANG;JunLIU;FuHengCHEN(DepatmetofAppliedChemistry,Beij... | Wang, MA Wang, M Liu, J Chen, FH Hong, SL Ma, LB | 1995 | Chinese Chemical Letters1995，6，8： | 3 |
| 5 | Some recent results in the theory of the Wiener number 显示文摘 | Gutman I Yeh YN Lee SL Chen JC | 1993 | Indian J Chem1993，32，： | 1 |
| 6 | Medial sural artery perforator flap for intraoral reconstruction following cancer ablation 显示文摘 | Chen SL Yu CC Chang MC | 2008 | Ann Plastic Surgery2008，61，3： | 1 |
| 7 | Distally based sural fasciomusculocutaneous flap for chronic calcaneal osteomyelitis in diabetic patients显示文摘 | Chen SL Chen TM Chou TD | 2005 | Ann Plast Surg2005，54，1： | 1 |
| 8 | The risk of unexplained antepartum stillbirth in second pregnancies following caesarean section in the first pregnancy显示文摘 | Wood SL Chen S Ross S | 2008 | B JOG2008，115，： | 1 |
| 9 | Ovarian damage after laparoscopic endometrioma excision might be related to the size of cyst显示文摘 | Tang Y Chen SL Chen X | 2013 | Fertil Steril2013，100，2： | 1 |
| 10 | NaCl-induced ahernations of cellular and tissue ion fluxes in roots of salt-resistant and sah-sensitive poplar species显示文摘 | Sun J Chen SL Da SX | | 0，，： | 1 |
| 11 | Relationship between geno- type and enzyme activity of glutathione S-transferases M1 and P1 in Chinese 显示文摘 | Zhong SL Zhou SF Chen X | 2006 | Eur J Pharm Sci2006，28，12： | 1 |
| 12 | Intensity modulated radiation therapy (IMRT) for nasopharyngeal cancer, update of the Memorial Sloan Kettering experience显示文摘 | Wolden SL Chen WC Pfister DG | 2006 | Int J Radiat Oncol Biol Phys2006，64，1： | 1 |
| 13 | Prevalence and risk factors of knee osteoarthritis in Huang - Pu District,Shanghai,China 显示文摘 | Du H Chen SL Bao CD | 2005 | Rheumatol Int2005，25，8： | 1 |
| 14 | Expression of CD4+CD25+regulatory T cells and Foxp3 in peripheral blood of patients with gastric carcinoma显示文摘 | Chen SL Cai SR Zhang XH | 2016 | J Biol Regul Homeost Agents2016，30，1： | 1 |
| 15 | National and regional trends in heart failure hospitalization and mortality rates for medicare beneficiaries显示文摘 | Chen J Normand SL Wang Y | 2011 | JAMA2011，306，： | 1 |
| 16 | Insulin Inhibits Dexamethasone Effect on Angiotensinogen Gene Expression and Induction of Hypertrophy in Rat Kidney Proximal Tubular Cells in High Glucose显示文摘 | Zhang SL Chen X Wei CC | 2002 | Endocrinology2002，143，： | 1 |
| 17 | Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchyrnal stem cell in patients with acute myocardial infarction显示文摘 | Chen SL Fang WW Ye F | 2004 | Am J Cardiol2004，94，1： | 1 |
| 18 | c-Kit (CD117)reactivity in extramedullary myeloid tumor/granulocytic sarcoma显示文摘 | J Chen RR Yanuck 3rd SL Abbondanzo | 2001 | Arch Pathol Lab Med2001，125，11： | 1 |
| 19 | Tetramethylpyrazine reduces ischemic brain injury in rats显示文摘 | Liao SL Kao TK Chen WY | 2004 | Neurosci Let2004，372，12： | 1 |
| 20 | Activation of nuclear factor kappa B in hepatitis C virus infection: implications for pathogenesis and hepatocarcino genesis显示文摘 | Tai Di Tsai SL Chen YM | 2000 | Hepatology2000，31，3： | 1 |
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