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| 1 | Draining Tangjiashan Barrier Lake after Wenchuan Earthquake and the flood propagation after the dam break显示文摘Tangjiashan Barrier Lake is one of the largest barrier lakes caused by the Wenchuan Earthquake. Its risk analysis, emergency plan and effect of the emergency plan are introduced in this paper. The dam height of Tangjiashan Barrier Dam is about 105 m, and the reservoir storage capacity is 3.2×108 m3. When the dam broke the flood peak were estimated to be larger than 48000 m3/s, which might cause a enormous disaster to the downstream cities and residents. A discharge channel with 13 m deep and 8 m wide was drug, so that the water may flow out of the lake before the dam breaks. As a result, the drainage and risk mitigation project are successful. During the drainage process, the flood peak was about 6500 m3/s, and about 1.6×108 m3 of water was drained off and the residual reservoir capacity was only 8.97×107 m3. A new channel with average width 100 m was formed, which can bear floods of 200 years frequency. The successful experience and the collected data can be used to deal with the similar natural disasters in future. | LIU Ning1, ZHANG JianXin2, LIN Wei3, CHENG WuYI4 & CHEN ZuYu5 1 Ministry of Water Resources of the People’s Republic of China, Beijing 100053, China 2 Bureau of Hydrology of the Ministry of Water Resources of the People’s Republic of China, Beijing 100053, China 3 Sichuan Hydrographic and Water Resources Survey Bureau Chengdu 610031, China 4 HydroChina Chengdu Engineering Corporation, Chengdu 610072, China 5 China Institute of Water Resources and Hydropower Research, Beijing 100044, China | 2009 | Science China(Technological Sciences)2009，52，4： | 29 |
| 2 | Modelling of multi-bodies in close proximity under water waves——Fluid resonance in narrow gaps显示文摘Viscous fluid model and potential flow model with and without artificial damping force(f=-μV,μ the damping coefficient and V the local averaging flow velocity) are employed in this work to investigate the phenomenon of fluid resonance in narrow gaps between multi-bodies in close proximity under water waves.The numerical results are compared with experimental data available in the literature.The comparison demonstrates that both the viscous fluid model and the potential flow model are able to predict the resonant frequency reasonably well.However the conventional potential flow model(without artificial damping term) significantly over-predicts the wave height in narrow gaps around the resonant frequency.In order to calibrate the appropriate damping coefficient used for the potential model and make it work as well as the viscous fluid model in predicting the resonant wave height in narrow gaps but with little computational efforts,the dependence of damping coefficient μ on the body geometric dimensions is examined considering the parameters of gap width Bg,body draft D,body breadth ratio Br and body number n(n = 2,3),where Br = BB/BA for the case of two bodies(Body A and Body B) with different breadths of BA and BB,respectively.It was confirmed that the damping coefficient used for the potential flow model is not sensitive to the geometric dimensions and spatial arrangement.It was found that μ∈ [0.4,0.5] may guarantee the variation of Hg/H0 with kh to be generally in good agreement with the experimental data and the results of viscous fluid model,where Hg is the excited wave height in narrow gaps under various dimensionless incident wave frequencies kh,H0 is the incident wave height,k = 2π/L is the wave number and h is the water depth. | LU Lin1,2,TENG Bin3,CHENG Liang 4,SUN Liang5 & CHEN XiaoBo6 1 Center for Deepwater Engineering,Dalian University of Technology,Dalian 116024,China 2 State Key Laboratory of Structural Analysis for Industrial Equipment,Dalian University of Technology,Dalian 116024,China 3 State Key Laboratory of Coastal and Offshore Engineering,Dalian University of Technology,Dalian 116024,China 4 School of Civil and Resource Engineering,The University of Western Australia,Crawly 6003,Australia 5 Centre for Offshore Research and Engineering,Department of Civil Engineering,National University of Singapore,117576,Singapore 6 Research Department,Bureau Veritas,Neuilly-Sur-Seine,92570,France | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，1： | 29 |
| 3 | Overexpression of P53 and its risk factors in esophageal cancer in urban areas of Xi′an显示文摘OverexpressionofP53anditsriskfactorsinesophagealcancerinurbanareasofXi′anQIAOGuiBin1,HANChengLong2,JIANGRenChao1,SUNChang?.. | QIAO GuiBin1, HAN ChengLong2, JIANG RenChao1, SUN ChangSheng3, WANG Yan3 and WANG YunJie3 | 1998 | World Journal of Gastroenterology1998，4，1： | 21 |
| 4 | TRAF-mediated regulation of immune and inflammatory responses显示文摘The tumor necrosis factor (TNF) receptor-associated factor (TRAF) family consists of six mammalian members,and is shown to participate in signal transduction of a large number of receptor families including TNF receptor family (TNFR) and Toll-like receptors-interleukin-1 receptors (TLR-IL-1R) family.Upon receptor activation,TRAFs are directly or indirectly recruited to the intracellular domains of these receptors.They subsequently engage other signaling proteins to activate inhibitor of κB kinase (IKK) complex,TRAF family member-associated NF-κB activator (TANK)-binding kinase 1 (TBK1) and inducible I κB kinase (IKK-i) (also known as IKKε),ultimately leading to activation of transcription factors such as NF-κB and interferon-regulatory factor (IRF) to induce immune and inflammatory responses. | WANG YaYa1,ZHANG Peng2,LIU YingFang2 & CHENG GenHong1 1 Department of Microbiology,Immunology & Molecular Genetics,University of California Los Angeles,609 Charles E.Young Drive East,Los Angeles,California 90095,USA 2 National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China | 2010 | Science China(Life Sciences)2010，53，2： | 19 |
| 5 | Efects of a bioartificial liver support system on a cetaminophen-induced acute liver failure canines显示文摘Seeinvitedcommentaryonpage286Subjectheadingsliversupportsystem;acuteliverfailure;canines;porcinehepatocytes;bioartificiallive... | XUE Yi Long 1, ZHAO Shi Feng 2, ZHANG Zuo Yun 1, WANG Yue Feng 1, LI Xin Jian 1, HUANG Xiao Qiang 3, LUO Yun 1, HUANG Ying Cai 4 and LIU Cheng Gui 1 | 1999 | World Journal of Gastroenterology1999，5，4： | 19 |
| 6 | The cloning of 3'-truncated preS/S gene from HBV genomic DNA and its expression in transgenic mice显示文摘INTRODUCTIONHepatitis B virus (HBV) is regarded as one of themain etiologic factors involved in the developmentof human hepatocellular carcinoma (HCC).The open reading frame (orf)of X gene of HBVencoded a transactivating factor is the evidence thatstrongly supported the notion that the X gene ofHBV DNA integrated in HCC genomic DNA couldcontribute to the carcinogenesis of liver cells byactivation of some related cellular genes | Yi Ping Hu~1 Yu Cheng Yao~1 Jian Xiu Li~1 Xin Min Wang~1 Hong Li~2 Zhong Hua Wang~1 Zhang Heng Lei~3 1 Department of Cell Biology,Second Military Medical University,Shanghai 200433,China 2 Department of Biology,Department of Basic Medicine,West-China University of Medical Sciences,Chengdu 610041,China 3 Department of Biology,North Sichuan Medical College,Nanchong 637007,China | 2000 | World Journal of Gastroenterology2000，6，5： | 18 |
| 7 | Design,analysis and control of hybrid excited doubly salient stator-permanent-magnet motor显示文摘In this paper,a new hybrid excited doubly salient stator-permanent-magnet motor is proposed,where both permanent magnets and DC field windings are located in the stator.In theory,the mathematical model and design method of the motor are developed.The corresponding output power equation and the relationship between the flux control capability and the extended speed range are deduced in details.By using an efficient 'one-step' three-dimensional(3D) finite element method,the electromagnetic performances are analyzed,in which the leakage flux outside the stator circumference and end-effect are taken into account.Based on the operation principle of the motor,the control strategy and scheme are developed and implemented experimentally.Both experimental results and finite element analysis show that the proposed motor not only maintains the advantages of doubly salient permanent magnet motors,but also offers high energy efficiency over a wide speed range,which makes the motor an interesting candidate for electric vehicles. | ZHU XiaoYong1,2 & CHENG Ming1 1 Engineering Research Center for Motion Control of MOE,School of Electrical Engineering,Southeast University,Nanjing 210096,China 2 School of Electrical and Information Engineering,Jiangsu University,Zhenjiang 212013,China | 2010 | Science China(Technological Sciences)2010，53，1： | 16 |
| 8 | Persistence of hepatitis B vaccine immune protection and response to hepatitis B booster immunization显示文摘AbstractAIMToidentifythepersistenceofimmuneprotectionofChinamade,plasmaderivedhepatitisBvaccineafterinfancyimmunizationandt... | LI Hui 1, LI Rong Cheng 2, LIAO Su Su 1, YANG Jin Ye 2, ZENG Xian Jia 1 and WANG Shu Sheng 2 | 1998 | World Journal of Gastroenterology1998，4，6： | 15 |
| 9 | Recent progress of solar physics research in China显示文摘Owing to the largely improved facilities and working conditions,solar physics research in China has recently shown marked development.This paper reports on the recent progress of solar physics research in China's Mainland,mainly focusing on several hot issues,including instrumentations,magnetic field observations and research,solar flares,filaments and their eruptions,coronal mass ejections and related processes,as well as active regions and the corona,small-scale phenomena,solar activity and its predictions.A vision of the future is also described. | Cheng Fang 1 School of Astronomy and Space Science,Nanjing University,Nanjing 210093,China 2 Key Laboratory of Modern Astronomy and Astrophysics(Nanjing University),Ministry of Education,China | 2011 | Research in Astronomy and Astrophysics2011，11，12： | 14 |
| 10 | Long-term efectiveness of infancy low-dose hepatitis B vaccine immunization in Zhuang minority area in China显示文摘METHODSTwoepidemiologicmethods,acrosssectionalfolowupstudyandacasecontrolstudy,wereusedfortheevaluationoftheserologicalef... | LI Hui 1, LI Rong Cheng 2, LIAO Su Su 1, GONG Jian 2, ZENG Xian Jia 1 and LI Yan Ping 2 | 1999 | World Journal of Gastroenterology1999，5，2： | 14 |
| 11 | Preliminary study on the production of transgenic mice harboring hepatitis B virus X gene显示文摘INTRODUCTIONDespiteoverwhelmingepidemiologicalevidencelinkingpersistentHepatitisBVirus(HBV)infectionandthedevelopmentofhepato... | ZHU Huan Zhang 1, CHENG Guo Xiang 2, CHEN Jian Qu 2, KUANG Shu Yuan 3, CHENG Yong 2, ZHANG Xin Li 1, Ll Hou Da 2, XU Shao Fu 2, SHI Jing Quan 1, QIAN Geng Sun 3 and GU Jian Ren 3 | 1998 | World Journal of Gastroenterology1998，4，6： | 14 |
| 12 | Power system low frequency oscillation monitoring and analysis based on multi-signal online identification显示文摘The advance in the wide-area measurement system (WAMS) is driving the power system to the trend of wide-area monitoring and control.The Prony method is usually used for low frequency oscillation online identification.However,the identified amplitude and phase information is not sufficiently used.In this paper,the amplitude is adopted to detect the occurrence of the oscillation and to obtain the mode observability of the sites.The phase is adopted to identify the oscillation generator grouping and to obtain the mode shapes.The time varying characteristics of low frequency oscillations are studied.The behaviors and the characters of low frequency oscillations are displayed by dynamic visual techniques.Demonstrations on the '11.9' low frequency oscillation of the Guizhou Power Grid substantiate the feasibility and the validation of the proposed methods. | YUAN Ye1,2,SUN YuanZhang2,CHENG Lin2,CHEN Gang2 & WANG Peng3 1 State Nuclear Electric Power Planning Design and Research Institute,Beijing 100032,China 2 State Key Laboratory of Power Systems,Deptment of Electrical Engineering,Tsinghua University,Beijing 100084,China 3 EEE School,Nanyang Technological University,Singapore | 2010 | Science China(Technological Sciences)2010，53，9： | 13 |
| 13 | RESEARCH ON THE EVALUATION METHOD OF FRICTION AND LUBRICATION IN DEEP DRAWING显示文摘The deformation characteristic of bland in deep drawing is discussed. It is pointed out that the friction and lubrication conditions in for drawing are different from that in mechanical motion or machine work or other plastic process. The common test methods in laboratories are analyzed. It shows that though all those test methods can test the friction coefficient, the probe test method is most suitable for the research of friction and lubrication and the process in deep drawing, for this method is identical with the actual work condition either from the test principle or deformation status of the blank. Last the successful application in the deep drawing simulator newly developed the the probe method are intro- duced in detail. | D. N. He, X. F. Yin, H. Z. Thao, D. L*, X. Y. Ruan, J. L. Cheng and J. Y. Jiang 1) Shanghai Jiao Tong University, National Die & Mold CAD E. R. C, Shanghai 200030, China 2) Shanghai Vopkswagen Automotive Company Ltd., Shanghai 201805, China Manuscript re | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 13 |
| 14 | Lithospheric seismic fabrics of Sulu ultrahigh-pressure metamorphic belt显示文摘Calibration of seismic reflectors appearing in the crust of the Chinese continent sci- entific drilling site can be completed through the correlation studies between direct evidences, such as the drill cores, and geophysical signatures; therefore the interpretation of geophysical data could produce reliable results of crustal structure and composition. On the other hand, there are two Cenozoic volcanoes close to the scientific drilling site; analyzing composition of xenoliths existent in the volcanoes and evaluating their seismic velocities can also offer information about the mantle and lower crust. After the calibration via cores and well-logging data, the seismic re- flectors appearing in the UHP belt can be caused by lithological changes within the UHP rock slice, ductile shearing rock-suites, and later fracture zones. Among these sources, ductile shearing resulted in displacement and detachment of original rock-sheets, producing some rock-interbeds of several hundred meters thick that are named the ductile shearing rock-suites. A suite consists of mylonized gneiss and eclogite slices that underwent shearing, becoming the major mechanism responsible to generate regional strong reflections. The UHP rock-slice is characterized by complicated structures and high density, high seismic velocity and high electri- cal resistivity, its thickness is usually less than 11 km. Velocity and density of the gneiss-layer beneath gradually tend to normal with increasing depth. Based on the xenoliths we can infer that the middle crust contains a lot of gneisses, and the lower crust consists of different granulites. The lithospheric mantle has multi-layer structures and consists mainly of spinal lherzolite and harzburgite, implying late Mesozoic lithospheric thinning. The seismic fabrics with different ori- gins were possible products of different geodynamic processes. For instance, the UHP rock-slice was produced by the UHP metamorphic process and the exhumation of subducted supercrustal rocks after the Triassic collision between the Yangtze and Sino-Korean cratons; whilst the ductile shearing rock-suites resulted from shearing deformation processes during the subduction and exhumation. The normal velocity below the UHP rock-slice was correlated with Mesozoic exten- sion processes in the area. Through careful calibration of seismic reflectors and analyzing xeno- liths, one can find the relationship between the causes of seismic reflectors and corresponding geodynamic processes, offering a new basis for reconstruction of regional dynamic evolution history. | YANG Wencai 1 , YANG Wuyang 1 , JIN Zhenmin 2 & CHENG Zhenyan 1 1. Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037, China 2. China University of Geosciences, Wuhan 430074, China | 2005 | Science China Earth Sciences2005，48，5： | 13 |
| 15 | Effect of Protein Kinase C on Proliferation and Apoptosis of T Lymphocytes in Idiopathic Thrombocytopenic Purpura Children显示文摘It is well-documented that T lymphocyte proliferation and apoptosis are abnormal in idiopathic thrombocytopenic purpura (ITP) children. However, the underlying regulation mechanisms especially in terms of signal transduction remain unknown. In this paper, we reported the changes of protein kinase C (PKC) activity in peripheral blood T lymphocytes and the effect of PKC on T lymphocyte proliferation and apoptosis. We demonstrated that in ITP children, the activator (PMA) and inhibitor (H-7) of PKC affected on T lymphocyte proliferation and apoptosis dramatically, but they altered little in healthy children. PKC activity was significantly enhanced in ITP children together with an increased expression of FasL on CD3+ T, CD4+ T and CD8+T cells, resulting in a positive correlation between PKC activity and the expression of FasL on T cells. While the PKC activity and the platelet count were negatively correlated. Taken together, our findings suggest that the PKC activation may enhance T lymphocytes activity, suppress T cell apoptosis and be involve in thrombocytes damage as a mechanism related to immune pathogenesis of ITP. | Changlin Wu~(1,2) Fang Liu~1 Xuemin Zhou~1 Zhengwei Cheng~1 Xiaomeng Yang~1 Hong Xiao~1 Qun Chen~1 Kangrong Cai~1 ~1Department of Microbiology and Immunology,Guangdong Medical College,Zhanjiang,Guangdong,524023,China ~2Corresponding to:Dr.Changlin Wu,Department of Microbiology and Immunology,Guangdong Medical College,2 Wen-Ming East Road,Zhanjiang,Guangdong,524023,China. | 2005 | Cellular & Molecular Immunology2005，2，3： | 12 |
| 16 | Restudies on Body Surface of Dung Beetle and Application of Its Bionics Flexible Technique显示文摘A scanning electron microscope was used to observe the structures of the setae on the surface of a dung beetle Copris ochus, Motschulsky. There are lots of setae on the body surface, especially on the ventral part surface and lateral to the legs which are different in size, arrangement and shape. These setae have different lengths and many thorns on the whole seta. The top ends of these setae stand up without furcations which direct uprightly towards the surface of the touched soil. By the method of removing these setae, getting the insect weight before and after digging into the dung we affirm farther that the setae on the beetle body surface form the anti-stick and non-adherent gentle interface. The soil machines and components made by imitating the gentle body surface of beetles have favorable non-adherent results. | Jiurong Sun 1, Jianqiao Li 2, Hong Cheng 1, Zhendong Dai 3, Luquan Ren 2 1.College of Life Sciences, Peking University, Beijing, 100871,P.R. China 2.Key Laboratory of Terrain-Machine Bionics Engineering (Ministry of Education,China), Jilin University at Nanling Campus, Changchun, 130022,P.R.China 3.College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016,P.R.China | 2004 | Journal of Bionic Engineering2004，1，1： | 12 |
| 17 | Effects of Fuzhenghuayu decoction on collagen synthesis of cultured hepatic stellate cells,hepatocytes and fibroblasts in rats显示文摘INTRODUCTIONLiverfibrosisisthecommonpathologicalfeatureofchronicliverdiseases,andiscloselyasociatedwithchangesoflivercelfunct... | LIU Cheng 1, LIU Ping 1, LIU Cheng Hai 1, ZHU Xiu Qing 1 and JI Guang 1 | 1998 | World Journal of Gastroenterology1998，4，6： | 11 |
| 18 | A LOOP DRAWBEAD RESTRAINING FORCE MODEL IN SHEET METAL DEEP DRAWING PROCESS显示文摘In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead force is one of the most important pa- rameters in sheet metal forming process control. This paper derives the model of loop drawbead restraining force (DBRF) using plastic forming theory, and gives the min imum blankholding force. Experiments are carried out to verify the proposed DBRF model. The good agreement between the calculated values and experiments data justi- fies the proposed loop drawbead restraining force model. | Y.J. Luo, S.P. Li, J.F. Zheng, D.N. He, Y.Q. Zhang, J.L. Cheng and J. Y. Jiang 1)National Mold & Die CAD Engineering Research Center, Shanghai 200030, China 2)Shanghai Volkswagen Automotive Company Ltd.(SVM), Shanghai 201805, China | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，5： | 11 |
| 19 | Syntheses of amphiphilic biodegradable copolymers of poly(ethyl ethylene phosphate) and poly(3-hydroxybutyrate) for drug delivery显示文摘Biodegradable and amphiphilic triblock copolymers poly(ethyl ethylene phosphate)-poly(3-hydroxybutyrate)-poly(ethyl ethylene phosphate) (PEEP-b-PHB-b-PEEP) have been successfully synthesized through ring-opening polymerization. The structures are confirmed by gel permeation chromatography and NMR analyses. Crystallization investigated by X-ray diffraction reveals that the block copolymer with higher content of poly(ethyl ethylene phosphate) (PEEP) is more amorphous, showing decreased crystallizability. The obtained copolymers self-assemble into biodegradable nanoparticles with a coreshell micellar structure in aqueous solution, verified by the probe-based fluorescence measurements and transmission electronic microscopy (TEM) observation. The hydrophobic poly(3-hydroxybutyrate) (PHB) block serves as the core of the micelles and the micelles are stabilized by the hydrophilic PEEP block. The size and size distribution are related to the compositions of the copolymers. Paclitaxel (PTX) has been encapsulated into the micelles as a model drug and a sustained drug release from the micelles is observed. MTT assay also demonstrates that the block copolymers are biocompatible, rendering these copolymers attractive for drug delivery. | CHENG Jing1 & WANG Jun2 1 Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, China 2 Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China | 2009 | Science China Chemistry2009，52，7： | 10 |
| 20 | Long-term eficacy of plasma-derived hepatitis B vaccine among Chinese children:a 12-year folow-up study显示文摘INTRODUCTIONToevaluatelongtermeficacyofaplasmaderivedhepatitisBvaccineandprovideevidencefordecisionmakingonthevaccineboost... | LIAO Su Su 1, LI Rong Cheng 2, LI Hui 1, YANG Jin Ye 2, ZENG Xian Jia 1, GONG Jian 2, WANG Shu Sheng 2, LI Yan Ping 2 and ZHANG Kong Lai 1 | 1999 | World Journal of Gastroenterology1999，5，2： | 9 |
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