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| 1 | The Sunway TaihuLight supercomputer: system and applications显示文摘The Sunway Taihu Light supercomputer is the world's first system with a peak performance greater than 100 PFlops. In this paper, we provide a detailed introduction to the Taihu Light system. In contrast with other existing heterogeneous supercomputers, which include both CPU processors and PCIe-connected many-core accelerators(NVIDIA GPU or Intel Xeon Phi), the computing power of Taihu Light is provided by a homegrown many-core SW26010 CPU that includes both the management processing elements(MPEs)and computing processing elements(CPEs) in one chip. With 260 processing elements in one CPU, a single SW26010 provides a peak performance of over three TFlops. To alleviate the memory bandwidth bottleneck in most applications, each CPE comes with a scratch pad memory, which serves as a user-controlled cache. To support the parallelization of programs on the new many-core architecture, in addition to the basic C/C++and Fortran compilers, the system provides a customized Sunway Open ACC tool that supports the Open ACC2.0 syntax. This paper also reports our preliminary efforts on developing and optimizing applications on the Taihu Light system, focusing on key application domains, such as earth system modeling, ocean surface wave modeling, atomistic simulation, and phase-field simulation. | Haohuan FU Junfeng LIAO Jinzhe YANG Lanning WANG Zhenya SONG Xiaomeng HUANG Chao YANG Wei XUE Fangfang LIU Fangli QIAO Wei ZHAO Xunqiang YIN Chaofeng HOU Chenglong ZHANG Wei GE Jian ZHANG Yangang WANG Chunbo ZHOU Guangwen YANG | 2016 | Science China(Information Sciences)2016，59，7： | 45 |
| 2 | The use of fire at Zhoukoudian:evidence from magnetic susceptibility and color measurements显示文摘In order to provide direct evidence for the use of fire by humans at Locality 1,Zhoukoudian,we examine the burnt and unburnt sediments of newly excavated area in Layer 4 by detailed measurements of magnetic susceptibility,color,and diffuse reflectance spectrum.Results show that the magnetic susceptibility and redness of the burnt sediments are remarkably higher than those of other areas on the same level:up to*22 times for magnetic susceptibility and*3 times for redness of those of the adjacent unburnt sediments.Fine-grained(superparamagnetic/stable single-domain)magnetite and hematite grains make dominant contributions to the distinctly high values of magnetic susceptibility and redness in the burnt sediments.Diffuse reflectance spectroscopy results show that the burnt sediments contain more hematite than those of other areas and localities 2 and 3.High-temperature magnetic susceptibility measurements demonstrate that the burnt sediments have been heated above 700°C.Those changes in low-frequency magnetic susceptibility and redness are impossibly resulted from natural fires,thus most likely signaling the human activities of controlled use of fire.However,further work is needed to confirm whether or not these heat-affected sediments were produced in situ. | Yan Zhang Zhengtang Guo Chenglong Deng Shuangquan Zhang Haibin Wu Chunxia Zhang Junyi Ge Deai Zhao Qin Li Yang Song Rixiang Zhu | 2014 | Chinese Science Bulletin2014，59，10： | 6 |
| 3 | Chartrenoline, a novel alkaloid isolated from a marine Streptomyces chartreusis NA02069显示文摘A novel alkaloid, chartrenoline(1), featuring an unusual 6/6/5/5-tetracyclic nucleus, was isolated from a marine Streptomyces chartreusis NA02069. The structure of 1 including its absolute configurations was established by extensive analyses of its high resolution mass, NMR and single-crystal X-ray diffraction data. A plausible biosynthetic pathway for chartrenoline(1) is proposed. | Chengli Liu Chenglong Yang Yingjie Zeng Jing Shi Lingyu Li Wei Li Ruihua Jiao Renxiang Tan Huiming Ge | 2019 | Chinese Chemical Letters2019，30，1： | 3 |
| 4 | Thermodynamics of Molten Pool Predicted by Computational Fluid Dynamics in Selective Laser Melting of Ti6Al4V:Surface Morphology Evolution and Densification Behavior显示文摘The three-dimensional physical model of the randomly packed powder material irradiated by the laser beam was established,taking into account the transformation of the material phase,the melt spreading and the interaction of the free surface of the molten pool and the recoiling pressure caused by the material evaporation during the selective laser melting.Influence of the processing parameters on the thermal behavior,the material evaporation,the surface morphology and the densification behavior in the connection region of the molten pool and the substrate was studied.It was shown that the powder material underwent the transformation from the partial melting state to the complete melting state and finally to the overheating state with the applied laser energy density increasing from 167 J/mm^(3) to 417 J/mm^(3).Therefore,the solidified track ranged from the discontinuous tracks with the rough surface to the continuous tracks with residual porosities,then to the continuous and dense tracks and terminally to the fluctuated tracks with the increase in the laser energy density.Meanwhile,the laser energy effect depth was maintained the positive relationship with the laser energy density.The vortex velocity obtained in the free surface of the molten pool towards to the rear region in the opposite laser scan direction promoted the melt convection to the edge region of the molten pool as the laser energy density was higher than 277 J/mm^(3),demonstrating the efficient energy dissipation from the center of the irradiation region to the whole part of the molten pool and the attendant production of the sufficient melt volume.Therefore,the efficient spreading of the molten pool and the metallurgical bonding ability of the melt with the substrate was obtained at the optimized laser energy density of 277 J/mm^(3).However,the severe material evaporation would take place as the melt was overheated,resulting in the formation of the residual pores and poor surface quality. | Donghua Dai Dongdong Gu Qing Ge Chenglong Ma Xinyu Shi Han Zhang | 2020 | Computer Modeling in Engineering & Sciences2020，，9： | 1 |
| 5 | Research on Real-Time High Reliable Network File Distribution Technology显示文摘The rapid development of Internet of Things(IoT)technology has made previously unavailable data available,and applications can take advantage of device data for people to visualize,explore,and build complex analyses.As the size of the network and the number of network users continue to increase,network requests tend to aggregate on a small number of network resources,which results in uneven load on network requests.Real-time,highly reliable network file distribution technology is of great importance in the Internet of Things.This paper studies real-time and highly reliable file distribution technology for large-scale networks.In response to this topic,this paper studies the current file distribution technology,proposes a file distribution model,and proposes a corresponding load balancing method based on the file distribution model.Experiments show that the system has achieved real-time and high reliability of network transmission. | Chenglong Li Peipeng Liu Hewei Yu Mengmeng Ge Xiangzhan Yu Yi Xin Yuhang Wang Dongyu Zhang | 2020 | Computers, Materials & Continua2020，，11： | 0 |
| 6 | New dating indicates intermittent human occupation of the Nwya Devu Paleolithic site on the high-altitude central Tibetan Plateau during the past 45,000 years显示文摘The timing and mechanisms of the human occupation of the demanding high-altitude Tibetan Plateau environment are of great interest.Here,we report on our reinvestigations and dating of the Nwya Devu site,located nearly 4600 meters above sea level on the central Tibetan Plateau.A new microblade techno-complex was identified on a lower lake shore at this site,distinct from the previously reported blade tool assemblage.These two lithic assemblages were dated to 45.6±2.6 and10.3±0.5 ka using optically stimulated luminescence and accelerator mass spectrometry^(14)C methods.They represent,respectively,the earliest known Paleolithic and microlithic sites on the interior Tibetan Plateau,indicating multiple occupation episodes of hunter-gatherers during the past 45 ka.Our studies reveal that relatively stable depositional conditions and a paleoenvironment characterized by a comparatively warm climate facilitated these multiple occupations at Nwya Devu.The contemporaneous occurrence of the Upper Paleolithic blade technology on the Tibetan Plateau and most of Eurasia between 50 and 40 ka indicates rapid,large-scale dispersals of humans that profoundly affected human demography on a large scale.Combining new archaeological evidence and previously reported genetic data,we conclude that the Tibetan Plateau provided a relatively stable habitat for Upper Paleolithic hunter-gatherers,which may have contributed to the complex and multiple-origin gene pool of present-day Tibetans. | Junyi GE Xiaoling ZHANG Shejiang WANG Linhui LI Wei HE Yingshuai JIN Peiqi ZhANG Bing XU Chenglong DENG John WOLSEN Zhengtang GUO Xing GAO | 2024 | Science China Earth Sciences2024，67，2： | 0 |
| 7 | Equipment remaining useful life prediction oriented symbiotic simulation driven by real-time degradation data显示文摘As an emerging simulation technology in the field of system modeling and simulation,the equipment symbiotic simulation has become research emphasis.In the field of equipment maintenance support,the outstanding problem of equipment remaining useful life(RUL)prediction is analyzed,i.e.,the stable model parameters without self-evolution ability,which has become the primary factor that hinders self-adaptive prediction of equipment RUL.Combined with parallel systems theory,the equipment RUL prediction oriented symbiotic simulation framework is proposed on the basis of modeling analysis and Wiener state space model(SSM)is taken as the basic simulation model in the framework.Driven by the dynamic injected equipment degradation observation data,the model parameters are updated online by using expectation maximum(EM)algorithm and the data assimilation between simulation outputs and observation data is executed by using Kalman filter,so as to realize dynamic evolution of the simulation model.The simulation model evolution which makes the simulation outputs close to equipment real degradation state provides high fidelity model and data for predicting equipment RUL accurately.The framework is verified by the performance degradation data of a bearing.The simulation results show that the symbiotic simulation method can accurately simulate the equipment performance degradation process and the self-adaptive prediction of equipment RUL is realized on the basis of improving prediction accuracy,proving the feasibility and effectiveness of symbiotic simulation method. | Chenglong Ge Yuanchang Zhu Yanqiang Di | 2018 | International Journal of Modeling, Simulation, and Scientific Computing2018，9，2： | 0 |
| 8 | MicroRNA-208a silencing against myocardial ischemia/reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes显示文摘MicroRNA-208a(miR-208a)plays critical roles in the severe fibrosis and heart failure post myocardial ischemia/reperfusion(IR)injury.MiR-208a inhibitor(mI)with complementary RNA sequence can silence the expression of miR-208a,while it is challenging to achieve efficient and myocardium-targeted delivery.Herein,biomimetic nanocomplexes(NCs)reversibly coated with red blood cell membrane(RM)were developed for the myocardial delivery of mI.To construct the NCs,membrane-penetrating helical polypeptide(PG)was first adopted to condense mI and form the cationic inner core,which subsequently adsorbed catalase(CAT)via electrostatic interaction followed by surface coating with RM.The membrane-coated NCs enabled prolonged blood circulation after systemic administration,and could accumulate in the injured myocardium via passive targeting.In the oxidative microenvironment of injured myocardium,CAT decomposed H_(2)O_(2)to produce O_(2)bubbles,which drove the shedding of the outer RM to expose the positively charged inner core,thus facilitated effective internalization by cardiac cells.Based on the combined contribution of mI-mediated miR-208a silencing and CAT-mediated alleviation of oxidative stress,NCs effectively ameliorated the myocardial microenvironment,hence reducing the infarct size as well as fibrosis and promoting recovery of cardiac functions.This study provides an effective strategy for the cytosolic delivery of nucleic acid cargoes in the myocardium,and it renders an enlightened approach to resolve the blood circulation/cell internalization dilemma of cell membrane-coated delivery systems. | Jianhui Lu Jiaheng Zhang Wen Yan Chenglong Ge Yang Zhou Rongying Zhu Shanzhou Duan Lichen Yin Yongbing Chen | 2023 | Nano Research2023，16，8： | 0 |
| 9 | Recent changing patterns of the Changjiang(Yangtze River) Estuary caused by human activities显示文摘To evaluate the controlling factors for coastline change of the Changjiang(Yangtze River) Estuary since 1974,we extracted the mean high tide line from multi-temporal remote sensing images that span from 1974 to 2014 at 2-year intervals.We chose 42 scenes to constrain the changing pattern of the Changjiang Estuary coastline,and implemented GIS technology to analyze the area change of the Changjiang(Yangtze) Subaerial Delta.Runoff,sediment discharge and coastal engineering were withal considered in the analysis of the coastline changes.The coastline has transgressed seaward since 1974,and a part of it presents inter-annual variations.The area of the Changjiang Subaerial Delta increased by 871 km2,with a net accretion rate of 21.8 km2/a.Based on the change of sediment discharge due to the major projects in the Changjiang River Basin,we divided the changing pattern of the coastline into three stages:the slow accretion stage(1974–1986),the moderate accretion stage(1987–2002),and the rapid accretion stage(2003–2014).Liner regression analysis illustrated that there is a significantly positive correlation between the area changes and sediment discharge in the Chongming Eastern Shoal and Jiuduansha.This suggested that sediment load has a fundamental effect on the evolution of the Changjiang Estuary.Construction of Deep Waterway in the North Passage of the Changjiang River(1998–2010) led to a rapid accretion in the Hengsha Eastern Shoal and Jiuduansha by influencing the hydrodynamics in North Passage.Coastal engineering such as reclamation and harbor construction can also change the morphology of the Changjiang Estuary.We defined a contribution rate of area change to assess the impact of reclamation on the evolution of Changjiang Estuary.It turned out that more than 45.3% of area increment of the Changjiang Estuary was attributed to reclamation. | WANG Chenglong ZHAO Yifei ZOU Xinqing XU Xinwanghao GE Chendong | 2017 | Acta Oceanologica Sinica2017，36，4： | 0 |
| 10 | Accelerated Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydride via Inorganic Nano-initiators显示文摘While the accelerated polymerization of N-carboxyanhydrides (NCAs) has been utilized to synthesize versatile polypeptide materials in an efficient manner with minimized side reactions, the preparation of polypeptide-based inorganic/organic hybrid materials with the acceleration strategy remained largely unexplored. Herein, we report the accelerated ring-opening polymerization (ROP) of NCAs mediated by amine-modified inorganic nano-initiators, such as mesoporous silica nanoparticles (MSN-NH2), which is driven by the cooperative effect of the neighboring α-helical polypeptide chains in a dichloromethane (DCM)/water biphasic system. Well-defined nano-hybrids were prepared within 15 min from non-purified NCA monomers, through in situ purification and subsequent ultrafast polymerization process. NCAs can be rapidly initiated by amino groups of MSN uniformly dispersed at the interface of DCM and water, and subsequently formed the well-defined polypeptides within 15 min. The prepared inorganic/organic nano-hybrid with MSN as the core and polypeptide as the shell adopted spherical morphology and uniform size distribution due to the excellent controllability of ROP. Besides, this system is also suitable for a variety of NCAs and inorganic nano-initiators. This research allows efficient and rapid preparation of inorganic/organic nano-hybrids, and further promotes the extensive application of this material in the biomedical fields. | Junliang Zhu Yunjie He Chenglong Ge Wenting Si Ziyuan Song Lichen Yin | 2023 | Chinese Journal of Chemistry2023，41，19： | 0 |
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