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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Expression of the cystic fibrosis transmembrane conductance regulator in rat spermatids: implication for the site of antispermatogenic agents显示文摘 | Gong X D Li J C Cheung K H | 2001 | Mol Hum Reprod2001，7，8： | 2 |
| 3 | Cervical Intervertebral Disc Degeneration Induced by Unbalanced Dynamic and Static Forces: A Novel In Vivo Rat Model显示文摘 | Yong-Jun Wang Qi Shi W W. Lu K C. M. Cheung Michael Darowish Tian-Fang Li Yu-Feng Dong Chong-Jian Zhou Quan Zhou Zhi-jun Hu Mei Liu Qin Bian Chen-Guang Li K D. K. Luk J C. Y. Leong | 2006 | Spine2006，，14： | 2 |
| 4 | Nitrogen and phosphorus leaching from fertilizer applied on golf course: Lysimeter study 显示文摘 | Wong J W C Chan C W Y Cheung K G | 1998 | Water Air and Soil Pollution1998，107，： | 1 |
| 5 | Indigenous Chinese personality constructs: Is the five factor model complete? 显示文摘 | CHEUNG F M LEUNG K ZI-IANG J X | 2001 | J Cross Cultural Psychol2001，32，40： | 1 |
| 6 | A note on discounted compound renewal sums under dependency 显示文摘 | Woo J K Cheung E C K | 2013 | Insurance: Mathematics and Economics2013，52，2： | 1 |
| 7 | Analgesic and sedalive effects of intranasal dexmedetomidine in third molar surgery un- der local anaesthesia显示文摘 | CHEUNG C W NG K F J LIU J | 2011 | Br J Anaesth2011，107，3： | 1 |
| 8 | Cytogenetics of multiple myeloma:interpretation of fluorescene in situ hybridization results显示文摘 | HARRISON C J MAZZULLO H CHEUNG K L | 2003 | Br J Haematol2003，120，： | 1 |
| 9 | Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+)mice due to attenuation of anti-oxidative stress path-way while potentiates inflammation 显示文摘 | CHEUNG K L LEE J H KHOR T O | 2014 | Mol Carcinog2014，53，1： | 1 |
| 10 | RNA expression analysis using a 30 base pair resolution Escherichia coli genome array显示文摘 | Selinger D W Cheung K J Mei R | 2000 | Nat Biotechnol2000，18，： | 1 |
| 11 | The prevalance of risk factors for back pain among home care nusing personnel in Hong Kong显示文摘 | Cheung K Gillen M Faucett J | 2006 | Am J Ind Med2006，49，1： | 1 |
| 12 | Numerical simulation of micro-bubble drag reductionusing population balance model显示文摘 | MOHANARANGAM K CHEUNG S C P TU J Y etal | 2009 | Ocean Engineering2009，36，： | 1 |
| 13 | Thermal stability and crystallization kinetics of iostactic polypropylene/organomontmorillonite nanocomposites 显示文摘 | He J D Cheung M K Yang M S | 2003 | J Appl Polym Sci2003，89，12： | 1 |
| 14 | Adaptive motion tracking block matching algorithms for video coding显示文摘 | XU J B PO L M CHEUNG C K | 1999 | IEEE Trans on Circuits and System for Video Technology1999，9，7： | 1 |
| 15 | Inhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand显示文摘 | YUAN J CHEUNG P K ZHANG H M | 2005 | J Virol2005，79，4： | 1 |
| 16 | Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line显示文摘 | Liu W K Ho J C Cheung F W | 2004 | Eur J Pharmacol2004，498，13： | 1 |
| 17 | Agglomerative fuzzy k- means clustering algorithm with selection of number of cluster 显示文摘 | M J Li M K Ng Y Cheung | 2008 | IEEE Transactions on Knowledge and Data Engineering2008，20，11： | 1 |
| 18 | The use of web- based learning for simulation - based education and training of central venous catheterization in novice learners 显示文摘 | Cheung J J Koh J Mackinnon K | 2013 | Stud Health Technol Inform2013，184，： | 1 |
| 19 | Does a positive ankle stress test in- dicate the need for operative treatment after lateral malleolus fracture? A preliminary report 显示文摘 | Koval K J Ego1 KA Cheung Y | 2007 | J Orthop Trauma2007，21，7： | 1 |
| 20 | Energy-efficient envelopedesign for high-rise apartments显示文摘 | Cheung C K Fuller R J Luther M B | 2005 | Energy and Buildings2005，37，1： | 1 |
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