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| 1 | Viral manipulation of cellular protein conjugation pathways: The SUMO lesson显示文摘Small ubiquitin-like modifier(SUMO)ylation is a key posttranslational modification mechanism that controls the function of a plethora of proteins and biological processes. Given its central regulatory role, it is not surprising that it is widely exploited by viruses. A number of viral proteins are known to modify and/or be modified by the SUMOylation system to exert their function, to create a cellular environment more favorable for virus survival and propagation, and to prevent host antiviral responses. Since the SUMO pathway is a multi-step cascade, viral proteins engage with it at many levels, to advance and favor each stage of a typical infection cycle: replication, viral assembly and immune evasion. Here we review the current knowledge on the interplay between the host SUMO system and viral lifecycle. | Domenico Mattoscio Chiara V Segré Susanna Chiocca | 2013 | World Journal of Virology2013，2，2： | 8 |
| 2 | 国际癌症研究机构工作组乳腺癌筛查简报显示文摘乳腺癌是导致全球女性死亡最常见的恶性肿瘤之一,而且超过一半发生在低至中等收入的国家。近年来在我国,特别是大中城市及沿海经济发展较快地区,乳腺癌已排在女性恶性肿瘤的第一位,是危害妇女健康的主要疾病。如何在早期筛查乳腺癌,以提高防癌效果,对社区及临床有重要意义。本期世界全科医学工作嘹望对2015—06-03在线发表于《新英格兰杂志》的《国际癌症研究机构(IARC)工作组乳腺癌筛查简报》进行了部分翻译,IARC对经乳腺钼靶X线摄影检查筛查乳腺癌的利弊进行了细致评估后,推荐50~69岁女性接受筛查利大于弊。同时,简报还对一般人群及乳腺癌高危人群采取不同方法进行乳腺癌筛查的利弊相关证据评价进行了总结,对全科医生和临床医师筛查工作提供了借鉴。 | Béatrice Lauby-Secretan Chiara Scoccianti Dana Loomis Lamia Benbrahim-Tallaa Véronique Bouvard Franca Bianchini Kurt Straif | 2015 | 中国全科医学2015，18，27： | 2 |
| 3 | Impact of testosterone on body fat composition 显示文摘 | CHIARA DE M STELLA V ANNA P | 2012 | J Cell Physiol2012，227，12： | 1 |
| 4 | Reward system and addiction:what dopamine does and doesn't do显示文摘 | Di Chiara G Bassareo V | 2007 | Curr Opin Pharmacol2007，7，1： | 1 |
| 5 | Action fluency in Parkinson's disease:a follow-up study显示文摘 | MATTEO S CHIARA V | 2006 | Movement Disorders2006，21，4： | 1 |
| 6 | Determinants of children's eating behavior显示文摘 | Silvia S Chiara A Fiamametta V | 2011 | Am J Clin Nutr2011，，： | 1 |
| 7 | Spectroscopy in the Z= 49 108,110In isotopes: Lifetime measurements in shears bands 显示文摘 | CHIARA C J FOSSAN D B JANZEN V P | 2001 | Physical Review C2001，64，： | 1 |
| 8 | Procalcitonin in acute car- diac patients显示文摘 | Claudio P Chiara L Serafina V | 2011 | Intern Emerg Med2011，6，3： | 1 |
| 9 | The diagnosis: and clas- sification of undifferentiated connective tissue diseases 显示文摘 | Marta M Chiara T Sabrina V | 2014 | Journal of autoimmunity2014，48，： | 1 |
| 10 | Differential Expression of Motivational Stimulus Properties by Dopamine in Nucleus Accumbens Shell versus Core and Prefrontal Cortex显示文摘 | Bassareo V De Luca MA Di Chiara G | 2002 | J Neurosci2002，22，11： | 1 |
| 11 | Early psychological adjustment in breast cancer patients-A prospective study显示文摘 | Chiara N Jonathan V R Timothy C | 2002 | J Psycho Res2002，53，6： | 1 |
| 12 | High cell density culti- vation of probioties and lactic acid production显示文摘 | CHIARA S VINEENZO VIVIEN V | 2002 | Biotechnology and Bioengineering2002，82，2： | 1 |
| 13 | A role for dopamine D1 receptors of the nucleus accumbens shell in conditioned taste aversion learning显示文摘 | Fenu S Bassareo V Di Chiara G | | 0，，17： | 1 |
| 14 | Structure of the C-ter- minal domain of Neisseria heparin binding antigen ( NHBA), oneof the main antigens of a novel vaccine against Neisseria meningit- idis显示文摘 | Esposito V Musi V de Chiara C | 2011 | J Biol Chem2011，286，41： | 1 |
| 15 | Surface lipids as multifunctional mediators of skin responses to environmental stimuli 显示文摘 | Chiara DL Giuseppe V | 2010 | Mediators Inflamm2010，210，： | 1 |
| 16 | Extracorporeal life support for out-of-hospital cardiac arrest:part of a treatment bundle显示文摘 | CHIARA L SERAFINA V ADRIANO P | 2015 | Eur Heart J:Acute Cardiovasc Care2015，25，： | 1 |
| 17 | If star scientists do not pa- tent : the effect of productivity, business and impact on the decision to patent in the academic world 显示文摘 | MARIO CHIARA F ANDREA V | 2007 | Research Policy2007，，36： | 1 |
| 18 | Spectroscopy in the Z=49 108,110 In isotopes:Lifetime measurements in shears bands显示文摘 | CHIARA C J FOSSAN D B JANZEN V P | 2001 | Physics Review C2001，64，05： | 1 |
| 19 | Determinants of chil- dren's eating hehavior显示文摘 | Silvia S Chiara A Fiammetta V | 2011 | Am J Clin Nutr2011，，： | 1 |
| 20 | Assessing alternative solutions to carbon leakage 显示文摘 | Antimiani A Costantini V Chiara M | 2013 | Energy Economics2013，36，： | 1 |
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