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| 1 | The Beneficial Effect of Regular Endurance Exercise Training on Blood Pressure and Quality of Life in Patients with Hypertension显示文摘 | Jen‐Chen Tsai Hung‐Yu Yang Wei‐Hsin Wang Ming‐Hsiung Hsieh Pei‐Ti Chen Ching‐Chiu Kao Pai‐Feng Kao Chia‐Hui Wang Paul Chan | 2004 | Clinical and Experimental Hypertension2004，，3： | 2 |
| 2 | Perihepatic nodes detected by point-of-care ultrasound in acute hepatitis and acute-on-chronic liver disease显示文摘AIM: To study the manifestations of perihepatic lymph nodes during the episode of acute hepatitis flare by point-of-care ultrasonography.METHODS: One hundred and seventy-six patients with an episode of acute hepatitis flare(ALT value > 5 × upper normal limit) were enrolled retrospectively. Diagnosis of etiology of the acute hepatitis flare was based on chart records and serological and virological assays. The patients were categorized into two groups(viral origin and non-viral origin) and further defined into ten subgroups according to the etiologies. An ultrasonograpy was performed within 2 h to 72 h(median, 8 h). The maximum size of each noticeable lymph node was measured. Correlation between clinical parameters and nodal manifestations was analyzed RESULTS: Enlarged lymph nodes(width ≥ 5mm)were noticeable in 110(62.5%) patients, mostly in acute on chronic hepatitis B(54.5%). The viral group had a higher prevalence rate(89/110 = 80.9%) and larger nodal size(median, 7 mm) than those of the non-viral group(21/66 = 31.8%; median, 0 mm)(P < 0.001 for both). Meanwhile, there were significant differences in the nodal size between acute and chronic viral groups(P < 0.01), and between acute hepatitis A and non-hepatitis A viral groups(P < 0.001). In logistical regression analysis, the nodal width still showed strong significance in multivariate analysis(P < 0.0001) to stratify the two groups. The area under the curve of ROC was 0.805, with a sensitivity of 80.9%, a specificity of 68.2%, positive predictive value of 80.92%, negative predictive value of 68.18%, and an accuracy of 76.14%. CONCLUSION: Point-of-care ultrasonography to detect perihepatic nodal change is valuable for clarifying the etiologies in an episode of acute hepatitis flare. | I Che Feng Szu Jen Wang Ming Jen Sheu Lok-Beng Koay Ching Yih Lin Chung Han Ho Chi Shu Sun Hsing Tao Kuo | 2015 | World Journal of Gastroenterology2015，21，44： | 2 |
| 3 | Control of Dkk‐1 ameliorates chondrocyte apoptosis, cartilage destruction, and subchondral bone deterioration in osteoarthritic knees显示文摘 | Lin‐HsiuWeng Ching‐JenWang Jih‐YangKo Yi‐ChihSun Feng‐ShengWang | 2010 | Arthritis & Rheumatism2010，，5： | 1 |
| 4 | 3G telecommunication operators' challenges and roles: A perspective of mobile commerce value chain 显示文摘 | KUO YING - FENG YU CHING - WEN | 2006 | Technovation2006，26，： | 1 |
| 5 | Corpo- rate social responsibility, investor protection, and earnings management: some international evidence显示文摘 | Hsiang - Lin Chih Chung - Hua Shen Feng - Ching Kang | 2008 | Journal of Business Ethics2008，79，： | 1 |
| 6 | Lipid Extract of Mycoplasma penetrans Proteinase K-Digested Lipid-Associated Membrane Proteins Rapidly Activates NF-κB and Activator Protein显示文摘 | Feng SH Ching Lo SC | 1999 | Infect Immun1999，67，6： | 1 |
| 7 | Reversal of doxorubicin resistance in lung cancer cells by neferine is explained by nuclear factor erythroid-derived 2-like 2 mediated lung resistance protein down regulation显示文摘Aim:Development of multi drug resistance and dose limiting cardiotoxicity are hindering the use of Doxorubicin(Dox)in clinical settings.Augmented dox efflux induced by lung resistance protein(LRP)over expression has been related to multi drug resistance phenotype in various cancers.An alkaloid from lotus,Neferine(Nef)shows both anticancer and cardioprotective effects.Here,we have investigated the interconnection between nuclear factor erythroid-derived 2-like 2(NRF2)and LRP in Dox resistance and how Nef can overcome Dox resistance in lung cancer cells by altering this signaling.Methods:Anti-proliferative and apoptotic-inducing effects of Nef and Dox combination in Parental and Dox resistant lung cancer cells were determined in monolayers and 3D spheroids.Intracellular Dox was analyzed using flow cytometry,siRNA knockdown and western blot analysis were used to elucidate NRF2-LRP crosstalk mechanism. | Poornima Paramasivan Jothi Dinesh Kumar Rathinasamy Baskaran Ching Feng Weng Viswanadha Vijaya Padma | 2020 | Cancer Drug Resistance2020，3，3： | 1 |
| 8 | Influence of surface modification on the dispersion of nanoscale ct - AI~O3 particles in a thermoplastic polyurethane matrix 显示文摘 | Cheng -Ho Chen Ching - Feng Mao Ming - Shyong Tsai Fu - Su Yen Jian - Min Lin Ching - Hui Tseng Heng - Yi Chen | 2008 | Journal of Applied Polymer Science2008，110，： | 1 |
| 9 | Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest显示文摘 | Paramasivan Poornima Ching Feng Weng Viswanadha Vijaya Padma | 2014 | BioFactors2014，，1： | 1 |
| 10 | Spinal Microglia Initiate and Maintain Hyperalgesia in a Rat Model of Chronic Pancreatitis显示文摘 | Pei–Yi Liu Ching–Liang Lu Chia–Chuan Wang I–Hui Lee Jen–Chuen Hsieh Chun–Chia Chen Hsing–Feng Lee Han–Chieh Lin Full–Young Chang Shou–Dong Lee | 2012 | Gastroenterology2012，，1： | 1 |
| 11 | Glucose-6-phosphate dehydrogenase deficiency, the UDP-glucuronosyl transferase 1A1 gene, and neonatal hyperbilirubinemia显示文摘 | Ching–Shan Huang Pi–Feng Chang May–Jen Huang En–Sung Chen Wu–Charng Chen | 2002 | Gastroenterology2002，，1： | 1 |
| 12 | Characteristics of the disinfection by- products (DBPs)and process control techniques of the disinfection process using preozonation and lmSt - chlorination显示文摘 | Chang Cheng - Nan Hsu Ching - Feng Chao A C | 1993 | Water Supply1993，13，34： | 1 |
| 13 | Actuator Fault And Ab- normal Operation Diagnoses For Auto-balancing Two-wheeled Cart Control 显示文摘 | Mi Ching Tsai Jia Sheng Hu Feng Rung Hu | 2009 | Mechatronics2009，19，5： | 1 |
| 14 | Applying the genetic approach to simulated annealing in solving some NP-hard problems 显示文摘 | Feng Tselin Cheng Yankao Ching Chihsu | 1993 | IEEE Transon SMC1993，6，： | 1 |
| 15 | CT and MR imaging characteristics of infantile hepatic hemangioendothelioma显示文摘 | Feng ST Chan T Ching AS | 2010 | European Journal of Radiology2010，76，2： | 1 |
| 16 | Metallothionein 3: An androgen‐upregulated gene enhances cell invasion and tumorigenesis of prostate carcinoma cells显示文摘 | Horng‐Heng Juang Li‐Chuan Chung Hsin‐Ching Sung Tsui‐Hsia Feng Yi‐Hua Lee Phei‐Lang Chang Ke‐Hung Tsui | 2013 | Prostate2013，，14： | 1 |
| 17 | A potential antitumor ellagitannin, davidiin, inhibited hepatocellular tumor growth by targeting EZH2显示文摘 | Yan Wang Jingyi Ma Sheung Ching Chow Chi Han Li Zhangang Xiao Ru Feng Jie Fu Yangchao Chen | 2014 | Tumor Biology2014，，1： | 1 |
| 18 | Upfront consolidation treatment with 131I-mIBG followed by myeloablative chemotherapy and hematopoietic stem cell transplantation in high-risk neuroblastoma显示文摘Importance:131I-metaiodobenzylguanidine(131I-mIBG)has a significant targeted antitumor effect for neuroblastoma.However,currently there is a paucity of data for the use of 131I-mIBG as a'front-line'therapeutic agent in those patients with newly diagnosed high-risk neuroblastoma as part of the conditioning regimen for myeloablative chemotherapy(MAC).Objective:To evaluate the feasibility of upfront consolidation treatment with 131I-mIBG plus MAC and hematopoietic stem cell transplantation(HSCT)in high-risk neuroblastoma patients.Methods:A retrospective,single-center study was conducted from 2003-2019 on newly diagnosed high-risk neuroblastoma patients without progressive disease(PD)after the completion of induction therapy.They received 131I-mIBG infusion and MAC followed by HSCT.Results:A total of 24 high-risk neuroblastoma patients were enrolled with a median age of 3.0 years at diagnosis.After receiving this sequential consolidation treatment,3 of 13 patients who were in partial response(PR)before 131I-mIBG treatment achieved either complete response(CR)(n=1)or very good partial response(VGPR)(n=2)after HSCT.With a median follow-up duration of 13.0 months after 131I-mIBG therapy,the 5-year event-free survival and overall survival rates estimated were 29%and 38%for the entire cohort,and 53%and 67%for the patients who were in CR/VGPR at the time of 131I-mIBG treatment.Interpretation:Upfront consolidation treatment with 131I-mIBG plus MAC and HSCT is feasible and tolerable in high-risk neuroblastoma patients,however the survival benefit of this 131I-mIBG regimen is only observed in the patients who were in CR/VGPR at the time of 131I-mIBG treatment. | Jianhua Feng Frankie WT Cheng Alex WK Leung Vincent Lee Eva WM Yeung Hoi Ching Lam Jeanny Cheung Grace KS Lam Terry TW Chow Carol LS Yan Chi Kong Li | 2020 | Pediatric Investigation2020，4，3： | 1 |
| 19 | Flow-injection spectrophotometric determination of mercury( Ⅱ ) in waterby the catalytic decomposition of ferrocyahide显示文摘 | Feng Yong Lai Narasaki Hisatake TianLi Ching | 1999 | Anal Sci1999，15，9： | 1 |
| 20 | Effect of fungal pellet size on the high yield production of destruxin B by Metarhizium anisopliae显示文摘 | FENG Kuo ching ROU 'Fzyy-min LIU Bing-lan | 2004 | Enzyme and Microbial Technol- ogy2004，34，1： | 1 |
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