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| 1 | Efficacy of thioguanine treatment in inflammatory bowel disease: A systematic review显示文摘AIM To critically assess the available literature regarding the efficacy of thioguanine treatment in inflammatory bowel disease(IBD) patients, irrespective of the(hepato-) toxicity profile.METHODS A systematic literature search of the MEDLINE database using Pub Med was performed using the keywords 'thioguanine', '6-TG', 'thioguanine', 'inflammatory bowel disease', 'IBD', 'Crohn's disease', 'Ulcerative colitis' and 'effectiveness' in order to identify relevant articles published in English starting from 2000. Reference lists of the included articles were crosschecked for missing articles. Reviewed manuscripts concerning the effectiveness of thioguanine treatment in IBD were reviewed by the authors and the data were extracted. Data were subsequently analyzed with descriptive statistics. Due to the lack of standardized outcomes, a formal meta-analysis was not performed.RESULTS A total of 11 applicable studies were found that involved the effectiveness of thioguanine therapy in IBD. Eight studies were conducted in a prospectivemanner, in the remaining three studies, data was collected retrospectively. In total, 353 IBD-patients(225 patients with Crohn's disease, 119 with ulcerative colitis and nine with unclassified IBD) with prior azathioprine/mercaptopurine resistance and/or intolerance(n = 321) or de novo thioguanine administration(n = 32) were included for analysis, of which 228(65%) had clinical improvement on thioguanine therapy, based on standard IBD questionnaires, biochemical parameters or global physician assessments. Short-term results were based on 268 treatment years(median follow-up 9 mo, range 3-22 mo) with a median daily dose of 20 mg(range 10-80 mg). Discontinuation, mostly due to adverse events, was reported in 72 patients(20%). CONCLUSION The efficacy of thioguanine therapy in IBD patients intolerant to conventional thiopurine therapy is observed in 65%, with short term adverse events in 20% of patients. | Berrie Meijer Chris JJ Mulder Godefridus J Peters Adriaan A van Bodegraven Nanne KH de Boer | 2016 | World Journal of Gastroenterology2016，22，40： | 5 |
| 2 | 导演张元采访录显示文摘 | Chris Berry | 2000 | 南京艺术学院学报(音乐与表演版)2000，，2： | 3 |
| 3 | 文革“样板戏”电影中的颜色显示文摘我们该如何评说文革'样板戏'电影中的红色呢?如今只要一提起'样板戏'就会让人联想到红色。我们都知道红色是共产主义革命的颜色。但是否还有别的可说呢?本文论证的是,尽管红色在这些电影中的确象征社会主义,但对红色的运用及其含义也有超出我们预期的其他可能性。主要英雄人物更倾向于穿白色而非红色。此外,女性的'学徒角色'(apprentice characters)最倾向于穿着红色,她们的角色身着在前革命时代象征着新娘的红色成为革命的新娘。本文还论证了颜色应被理解为既是含义也是动力(force),这种动力与剪接、构图、音乐、灯光,以及其他元素一起,合力为观众打造出具象参与(embodied engagement)的模式。这一来自象征含义的具象参与的自主性可以帮助我们理解,在这些作品摆脱了当初的政治含义之后很长时间还会持续流行的原因。不过,在表演这些作品的时候不唤起对那些象征含义的回忆是不可能的,这也有助于解释今天红色狂热所引起的不安。 | Chris Berry 王艺 | 2012 | 戏曲艺术2012，33，3： | 2 |
| 4 | China's New 'Women's Cinema'显示文摘 | Berry Chris | 1988 | Camera Obscura1988，，18： | 1 |
| 5 | 占有者是被剥夺者———《下女》(1960年)与金绮泳的价值重估显示文摘在韩国著名导演金绮泳执导的32部电影中,《下女》是最著名的一部,被公认为“韩国三大电影之一”。《汉江怪物》的导演奉俊昊宣称该片为韩国电影史上的《公民凯恩》。《下女》的意义体现在五个方面:第一,抓住了韩国的时代精神;第二,确立了金绮泳作为作者导演及其品牌的地位;第三,开创了韩国电影的恐怖片类型;影片的许多元素不仅出现在金绮泳对该片的四次翻拍中,也出现在1998年金绮泳去世后上映的翻拍片中,在韩国的许多恐怖电影中,某些元素也被多次借用。这种持久的生命力表明该片不仅建立了金绮泳的导演品牌,也建构了韩国恐怖片的许多关键模式;第四,引发了对韩国电影史的重估;第五,这部电影的长期吸引力和受其启发的许多电影表明,该片不仅在1960年成为社会批评和票房轰动的重要文化事件,而且与当今时代也产生了积极的共鸣。 | 裴开瑞(Chris Berry) 柳迪善(译) | 2023 | 贵州大学学报(艺术版)2023，37，3： | 0 |
| 6 | How I treat my inflammatory bowel disease-patients with thiopurines?显示文摘Thiopurines are essential drugs to maintain remission in patients with inflammatory bowel disease(IBD).Thiopurines used in IBD are azathioprine(2.0-2.5 mg/kg),mercaptopurine(1.0-1.5 mg/kg) and thioguanine(0.2-0.3 mg/kg).However,mainly due to numerous adverse events associated with thiopurine use,almost 50% of the patients have to discontinue conventional thiopurine treatment.Extensive monitoring and the application of several treatment strategies,such as split-dose administration,co-administration with allopurinol or dose reduction/increase,may increase the chance of successful therapy.With this review,we provide practical information on how thiopurines are initiated and maintained in two thiopurine research centers in The Netherlands.We provide clinical information concerning safety issues,indications and management of therapy that may serve as a guide for the administration of thiopurines in IBD patients in daily practice. | Berrie Meijer Chris JJ Mulder Adriaan A van Bodegraven Nanne KH de Boer | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，4： | 0 |
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