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| 1 | It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis显示文摘Background There is concern that blood pressure(BP)lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis.We assessed the effect of glyceryl trinitrate(GTN)in patients with carotid stenosis using data from the Efficacy of Nitric Oxide in Stroke(ENOS)Trial.Methods ENOS randomised 4011 patients with acute stroke and raised systolic BP(140-220 mm Hg)to transdermal GTN or no GTN within 48 hours of onset.Those on prestroke antihypertensives were also randomised to stop or continue their medication for 7 days.The primary outcome was the modified Rankin Scale(mRS)at day 90.Ipsilateral carotid stenosis was split:<30%;30-<50%;50-<70%;≥70%.Data are ORs with 95%CIs adjusted for baseline prognostic factors.results 2023(60.5%)ischaemic stroke participants had carotid imaging.As compared with<30%,≥70%ipsilateral stenosis was associated with an unfavourable shift in mRS(worse outcome)at 90 days(OR 1.88,95%CI 1.44 to 2.44,p<0.001).Those with≥70%stenosis who received GTN versus no GTN had a favourable shift in mRS(OR 0.56,95%CI 0.34 to 0.93,p=0.024).In those with 50-<70%stenosis,continuing versus stopping prestroke antihypertensives was associated with worse disability,mood,quality of life and cognition at 90 days.Clinical outcomes did not differ across bilateral stenosis groups.Conclusions Following ischaemic stroke,severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days.GTN appears safe in ipsilateral or bilateral carotid stenosis,and might improve outcome in severe ipsilateral carotid stenosis. | Jason P Appleton Lisa J Woodhouse Andrew Belcher Daniel Bereczki Eivind Berge Valeria Caso Hui Meng Chang Hanne K Christensen Ronan Collins John Gommans Ann C Laska George Ntaios Serefnur Ozturk Gillian M Sare Szabolcs Szatmari Yongjun Wang Joanna M Wardlaw Nikola Sprigg Philip M Bath for the ENOS investigators | 2019 | Stroke & Vascular Neurology2019,4,1: | 6 |
| 2 | 异型Ti电极直接乙醇燃料电池的制备与性能显示文摘采用Pt/C作为阴极催化剂,PtRu/C作为阳极催化剂,Nafion115和Nafion液涂覆膜作为质子交换膜,管状Ti丝(管)和平板式Ti网作为制备异型直接乙醇燃料电池的阴极和阳极的载体材料,制备管状阴极和平板阳极.观察了异型阴极和阳极的组织和结构,并通过单电池试验,研究了异型电极对直接乙醇燃料电池(DEFCs)性能的影响.结果表明,管状阴极涂覆的Nafion膜均匀一致,阳极催化剂与Ti网的结合能力较强,较高的O2流量有利于提高DEFCs单电池的性能,当膜载量达到25.0 mg/cm2以上时,会提高DEFCs单电池阻抗,当膜载量小于20.2 mg/cm2时,电池的使用寿命大大降低. | 倪红军 汪兴兴 汤东 李飞 Christensen P A | 2010 | 江苏大学学报(自然科学版)2010,31,5: | 4 |
| 3 | Effect of small scale solids migration in filter cake duringfiltration of wastewater solid suspensions 显示文摘 | Sorensen P B Christensen J R Bruus J H | 1995 | Wat Environ Res1995,69,1: | 2 |
| 4 | Pneumocystis murina infection and cigarette smoke exposure interact to cause increased organism burden,development of airspace enlargement,and pulmonary Inflammation in mice显示文摘 | Christensen P J Preston A M Ling T | 2008 | Infect Immun2008,76,8: | 1 |
| 5 | Sperm chromatin structure integrity in liquid stored boar semen and its relationships with field fertility 显示文摘 | BOE HANSEN G B CHRISTENSEN P VIVJERG D | 2008 | Theriogenology2008,69,6: | 1 |
| 6 | Measurement of soil microbial biomass provides an early indication of chan- ges in total soil organic matter due to straw in corporation 显示文摘 | Powlson D S Brookes P C Christensen B | 1987 | Soil Biol Bioehem1987,19,: | 1 |
| 7 | Recent developments in inductively coupled plasma magnetic sector multiple collector mass spectrometry 显示文摘 | Halliday A N Lee D C Christensen J N Walder A J Freedman P A Jones C E Hall C M Yi W Teagle D | 1995 | Int J Mass Spec Ion Proc1995,,: | 1 |
| 8 | A comparison of three methods of extracting resonance information from predictor-coefficient coded speech显示文摘 | CHRISTENSEN R L SREONG W J PALMER E P | 1976 | IEEE Transactions on ASSP1976,24,1: | 1 |
| 9 | Carbon footprint-a catalyst for life cycle assessment 显示文摘 | WEIDEMA B P THRANE M CHRISTENSEN P | 2008 | Journal of Industrial Ecology2008,12,1: | 1 |
| 10 | The importance of lytic and nonlytic immune responses in viral infections显示文摘 | Wodarz D Christensen J P Thomsen A R | 2002 | Trends Immunol2002,23,: | 1 |
| 11 | Perineal repair after extralevator abdominoperineal excision for low rectal cancer显示文摘 | Christensen HK Nerstr(o)m P Tei T | 2011 | Dis Colon Rectum2011,54,: | 1 |
| 12 | Fluids in hydrocarbon basins显示文摘 | Pedersen K S Christensen P L | 2007 | Reviews in Mineralogy and Geochemistry2007,65,1: | 1 |
| 13 | Enhanced diffusion of polycyelic aromatic hydrocarbons in artificial and natural aqueous solutions 显示文摘 | Mayer P Fernqvist M M Christensen P | 2007 | Environmental Science and Technology2007,41,17: | 1 |
| 14 | Acetylenes and related compounds in Cynareae 显示文摘 | Christensen L P Lam J | 1990 | Phytochemistry1990,29,9: | 1 |
| 15 | Measurement of soil microbial biomass provides an early indication of changes in total soil organic matter due to straw incorporation显示文摘 | Powlson D S Brookes P C Christensen B T | 1987 | Soil Biology and Biochemistry1987,19,: | 1 |
| 16 | Porcine lgA allotypes are not equally transcribed or expressed in heterozygous swine 显示文摘 | Navarro P Christensen R K Weber P | 2000 | Molecular-Immunology2000,37,11: | 1 |
| 17 | Health promoting compounds in vegetables and fruits: A systematic approach for identifying plant components with impact on human health 显示文摘 | Brandt K Christensen L P Hansen-Moller J | 2004 | Trends in Food Science & Technology2004,15,: | 1 |
| 18 | Distribution Coefficients of Cd,Co,Ni and Zn in Soils显示文摘 | Anderson P R Christensen T H | 1988 | Journal of Soil Science1988,39,: | 1 |
| 19 | A critical review of Li/air bat-teries显示文摘 | CHRISTENSEN J ALBERTUS P | 2012 | Journal of the Electrochemical Society2012,159,2: | 1 |
| 20 | Re- sponse characteristics and application of cha]cogenide glass Cr ( IV ) selective electrode 显示文摘 | Christensen J H Clemmesen P Hansen G H | 1997 | Sensor Actuat B: Chem1997,45,3: | 1 |