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6篇 您的检索式：作者名="Christian Melle"

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		题名	作者	年代	出处	被引量
	1	Population Pharmacokinetic Modeling of Hydromorphone in Cardiac Surgery Patients during Postoperative Pain Therapy显示文摘	Christian Jeleazcov Teijo I. Saari Harald Ihmsen Jan Mell Katharina Fr?hlich Ljubica Krajinovic J?rg Fechner Jürgen Schüttler	2014	Anesthesiology2014，，2：	2
	2	Detection and identification of protein interactions of S100 proteins by Protein Chip technology显示文摘	Roland Lehmann Christian Melle Niko Escher	2005	Journal of Proteome Research2005，4，5：	1
	3	A Technical Triadc for Proteomic Identification and Characterization of Cancer Biomarkers 显示文摘	Christian Melle Guonther Ernst Bettina Sehimmel	2004	CANCER RESEARCH2004，64，：	1
	4	Prospective comparison of MR enteroclysis with multidetector spiral-CT enteroclysis: interobserver agreement and sensitivity by means of 'sign-by-sign' correlation显示文摘	Sabine Schmidt Domenico Lepori Jean-Yves Meuwly Bertrand Duvoisin Reto Meuli Pierre Michetti Christian Felley Pierre Schnyder Guy van Melle Alban Denys	2003	European Radiology2003，，6：	1
	5	Prospective comparison of MR enteroclysis with multidetector spiral-CT enteroclysis: interobserver agreement and sensitivity by means of 'sign-by-sign' correlation显示文摘	Sabine Schmidt Domenico Lepori Jean-Yves Meuwly Bertrand Duvoisin Reto Meuli Pierre Michetti Christian Felley Pierre Schnyder Guy van Melle Alban Denys	2003	European Radiology2003，，6：	1
	6	CXCR5^(+)PD-1^(++)CD4^(+)T cells colonize infant intestines early in life and promote B cell maturation显示文摘Gastrointestinal infections are a major cause for serious clinical complications in infants.The induction of antibody responses by B cells is critical for protective immunity against infections and requires CXCR5+PD-1++CD4+T cells(TFH cells).We investigated the ontogeny of CXCR5+PD-1++CD4+T cells in human intestines.While CXCR5+PD-1++CD4+T cells were absent in fetal intestines,CXCR5+PD-1++CD4+T cells increased after birth and were abundant in infant intestines,resulting in significant higher numbers compared to adults.These findings were supported by scRNAseq analyses,showing increased frequencies of CD4+T cells with a TFH gene signature in infant intestines compared to blood.Co-cultures of autologous infant intestinal CXCR5+PD-1+/−CD4+T cells with B cells further demonstrated that infant intestinal TFH cells were able to effectively promote class switching and antibody production by B cells.Taken together,we demonstrate that functional TFH cells are numerous in infant intestines,making them a promising target for oral pediatric vaccine strategies.	Ana Jordan-Paiz Glòria Martrus Fenja L.Steinert Max Kaufmann Adrian F.Sagebiel Renée R.C.E.Schreurs Anne Rechtien Martin E.Baumdick Johannes M.Jung Kimberly J.Möller Lucy Wegner Cordula Grüttner Laura Richert Roland Thünauer Jennifer Schroeder-Schwarz Johannes Bvan Goudoever Teunis B.H.Geijtenbeek Marcus Altfeld Steven T.Pals Daniel Perez Paul L.Klarenbeek Christian Tomuschat Guido Sauter Ingo Königs Udo Schumacher Manuel A.Friese Nathaniel Melling Konrad Reinshagen Madeleine J.Bunders	2023	Cellular & Molecular Immunology2023，20，2：	0

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