4篇
您的检索式：作者名="Christian Moller"
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| 1 | Conversation dependence of the branching density of the polycondensation of ABn monomers显示文摘 | Uwe Beginn Christian Drohmann Martin Moller | 1997 | Macromolecules1997，30，： | 1 |
| 2 | In vitro selection for oleic and linoleic acid content in segregation populations of microspore derived embryos of Brassica napus显示文摘 | Christian Mollers Beate Rucker Dieter Stelling | 2000 | Euphytica2000，112，： | 1 |
| 3 | Light-stabilized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1显示文摘The precise regulation of microRNA(miRNA)biogenesis is crucial for plant development,which requires core microprocessors and many fine tuners to coordinate their miRNA processing activity/specificity in fluctuating cellular environments.During de-etiolation,light triggers a dramatic accumulation of core microprocessors and primary miRNAs(pri-miRNAs)but decreases pri-miRNA processing activity,resulting in relatively constant miRNA levels.The mechanisms underlying these seemingly contradictory regulatory changes remain unclear.In this study,we identified forkhead-associated domain 2(FHA2)as a light-stabilized suppressor of miRNA biogenesis.We found that FHA2 deficiency increased the level of mature miRNAs,accompanied by a reduction in pri-miRNAs and target mRNAs.Biochemical assays showed that FHA2 associates with the core microprocessors DCL1,HYL1,and SE,forming a complex to suppress their pri-miRNA processing activity.Further analyses revealed that FHA2 promotes HYL1 binding but inhibits the binding of DCL1-PAZ-RNase-RNA-binding domains(DCL1-PRR)to miRNAs,whereas FHA2 does not directly bind to these RNAs.Interestingly,we found that FHA2 protein is unstable in the dark but stabilized by light during de-etiolation.Consistently,disruption of FH A led to defects in light-triggered changes in miRNA expression and reduced the survival rate of deetiolated seedlings after prolonged light deprivation.Collectively,these data suggest that FHA2 is a novel light-stabilized suppressor of miRNA biogenesis and plays a role in fine-tuning miRNA processing during de-etiolation. | Seung Jun Park Suk Won Choi Gu Min Kim Christian Moller Hyun-Sook Pai Seong Wook Yang | 2021 | Molecular Plant2021，14，4： | 1 |
| 4 | Complex Regulation of Prolyl-4-Hydroxylases Impacts Root Hair Expansion显示文摘根头发是由尖端生长,与花粉试管分享的一个过程,轴突,和真菌的 hyphae 发展的单个房间。然而,结构的植物细胞墙强加限制完成尖端生长。除了多糖,植物房间墙由 hydroxyproline 富有的 glycoproteins (HRGP ) 组成,它包括几组 O-glycoproteins,包括 extensins (EXT ) 。脯氨酸 hydroxylation, HRGP 的早 translational 以后修正(PTM ) 由 prolyl 4-hydroxylases (P4Hs ) 催化,定义他们的随后的 O-glycosylation 地点。在这个工作,我们的基因分析证明那 P4H5,并且到更小的程度 P4H2 和 P4H13,为根头发尖端生长是枢轴的。第二,我们证明 P4H5 把 invitro 比较喜欢为 EXT 底层而非为另外的 HRGP 的特性。第三由交换途径的 P4H 倡导者和蛋白质, weshow 那 P4H2 和 P4H13 有可互换的功能,但是不能代替 P4H5。这三 P4Hs 被显示被指向到能分泌的小径,在 P4H5 与 P4H2 和 P4H13 形成 dimers 的地方。最后,我们在房间墙建筑学上探索缺乏的脯氨酸 hydroxylation 的影响。一起拿,我们的结果支持在哪个在 EXT 上改正 peptidyl 脯氨酸 hydroxylation 的一个模型,并且可能在另外的 HRGP,在 Arabidopsis thaliana 为自己组装的合适的房间墙和因此根头发延伸被要求。 | Silvia M. Velasauez Martiniano M. Ricardi Christian Peter Poulsen Ai Oikawa Adiphol Dilokpimol Adnan Halim Silvina Mangano Silvina Paola Denita Juarez Eliana Marzol Juan D. Salgado Salter Javier Gloazzo Dorosz Cecilia Borassi Svenning Rune Moller Rafael Buono Yukiko Ohsawa Ken Matsuoka Marisa S. Otegui Henrik V. Scheller Naomi Geshi Bent Larsen Petersen Norberto D. lusem Jose M. Estevez | 2015 | Molecular Plant2015，8，5： | 0 |
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