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| 1 | Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer显示文摘AIM: To evaluate the M1 and M2 monocyte phenotype in patients with non-small cell lung cancer(NSCLC) compared to controls. Also, to examine the expression of Th1 and Th2 cytokines in plasma of NSCLC vs controls. METHODS: Freshly prepared peripheral blood mononuclear cells samples were obtained from patients with NSCLC(lung adenocarcinoma and squamous cell lung carcinoma) and from non-cancer controls. Flow cytometry was performed to investigate M1 and M2 phenotypes in peripheral monocytes(classical monocytes CD14+, CD45+ and CD16-) using conventional surface markers. Th1 and Th2 cytokine production was alsoanalysed in the plasma using cytometric bead array technique. RESULTS: There were no significant difference in expression of M1(HLA-DR) and/or M2 markers(CD163 and CD36) markers on classical monocytes in patients with NSCLC compared to non-cancer controls. Expression of CD11 b, CD11 c, CD71 and CD44 was also shown to be similar in patients with NSCLC compared to noncancer controls. Th1 and Th2 cytokines [interleukin(IL)-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12(p70), tumor necrosis factor(TNF)-α, TNF-β, and interferon-γ] analysis revealed no significant difference between patients with NSCLC and non-cancer controls. CONCLUSION: This study shows no alteration in peripheral monocyte phenotype in circulating classical monocytes in patients with NSCLC compared to noncancer controls. No difference in Th1 and Th2 cytokine levels were noted in the plasma of these patients. | Saleh A Almatroodi Christine F Mc Donald Allison L Collins I an A Darby Dodie S Pouniotis | 2014 | World Journal of Clinical Oncology2014，5，5： | 2 |
| 2 | MSCs engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects显示文摘 | Luis A Frederica G Christine MC | 2003 | PNAS2003，100，： | 1 |
| 3 | Evaluation of a sequential extraction procedure for the speciation of heavy metals in sediments显示文摘 | Rhodri P Thomas Sharon E Mc Vey | 1994 | Anal Chim Acta1994，291，： | 1 |
| 4 | Does regular massage from late pregnancy to birth decrease maternal pain perception during labour and birth?—A feasibility study to investigate a programme of massage, controlled breathing and visualization, from 36 weeks of pregnancy until birth显示文摘 | Mary T. Mc Nabb Linda Kimber Anne Haines Christine McCourt | 2006 | Complementary Therapies in Clinical Practice2006，，3： | 1 |
| 5 | Rab39a binds caspase - 1 and is required for caspase - 1 - dependent interleukin - I beta secretion 显示文摘 | Christine EB Emma MC Luke AJ | 2009 | J Biol Chem2009，284，34： | 1 |
| 6 | The ABO blood group system and plasmodium falciparum malaria显示文摘 | Christine MC Walter HD | 2007 | Blood2007，110，22： | 1 |
| 7 | Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination显示文摘 | Ruth MH Christin MC | 1995 | Mol Microbiol1995，15，4： | 1 |
| 8 | Principal Component Analysis:A Versatile Method for Processing and Investigation of XPS Spectra显示文摘 | Kevin M. Mc Evoy Michel J. Genet Christine C. Dupont-Gil ain | | 0，，： | 1 |
| 9 | Ptosis associated with botulinum toxin treatment of strabismus and blepharospasm显示文摘 | Christine L Burns CL Gammon JA GemmilL MC | 1986 | Ophthalmology1986，93，： | 1 |
| 10 | Health communication on the internet:an effective channel for health behavior change?显示文摘 | Michael MC Christine J Brian C | 1998 | Journal of Health Communication1998，3，： | 1 |
| 11 | Effect of matrix metalloproteinases activity on outflow in perfused human organ culture显示文摘 | Bradley JMB Janice V Christine MC | 1998 | Invest Ophthalmol Vis Sci1998，39，： | 1 |
| 12 | 第一站,葡萄牙显示文摘预算不高,免费飞机餐使我兴奋不已;沉重的行囊背上身,差点叫我仰翻过去;早高峰的异国公交上,周围乘客的脸看起来都很“欧洲”;阴冷的早晨,在林中乱逛的我被老男人尾随,吓得魂飞魄散;蜷缩在咖啡馆里,十分想家,但又因温暧而觉得满足;不知自己有没有设置错闹钟,担心了一夜结果睡过头,错过飞机的我在机场号啕大哭……这些趣事、囿事、傻事通通都发生在我18岁那年的葡萄牙之旅。 | Christine Mc Cafferty 张健 | 2016 | 英语学习2016，0，9： | 0 |
| 13 | 欢喜大团圆显示文摘这于我而言的确是个奇怪的场景:在一个异域国度,她站在一个如明信片风景图般的?古老旅店边,腰上系着一条围裙,远远地在那里等我。“这是我最好的朋友。” | Christine MC Cafferty 木沐 | 2017 | 英语学习2017，0，2： | 0 |
| 14 | 到南半球去显示文摘在明媚的阳光下,我看见地面上有很多房子和泳池,也散布着森林和乡村。城市沿着海岸矗立,但与环绕着它的广阔天地相比却显得小了许多。海是一汪耀眼的蓝色。感觉棒极了,仿佛这就是我的家。 | Christine Mc Cafferty 鹿尤 | 2016 | 英语学习2016，0，7： | 0 |
| 15 | 遇见古老的英格兰显示文摘作者Christine与好友Shannon终于相见了,在英格兰泰晤士河边的小镇里,她们打算边工作边游览,可是事情并不像作者想的那样简单。小镇古香古色,中世纪英伦风十足,又充满了文化底蕴,可是Christine的工作却不太顺利,她们的室友又总是自以为是,面对这些不快,她们最后会怎么办呢? | Christine Mc Cafferty 魏聪 | 2017 | 英语学习2017，0，3： | 0 |
| 16 | 向着空档年,出发!显示文摘1.gapyear:(高中毕业后与进入大学前的)间隔年,空档年。2.lightsout:就寝时间。3.cover:被子,毯子。4.torch:手电筒。5.dreary:沉闷的,枯燥无味的;set off:启程,出发。6.budget:价格低廉的;eatery:餐馆。 | Christine Mc Cafferty | 2016 | 英语学习2016，0，8： | 0 |
| 17 | 失败的赌局显示文摘看雪的愿望实现后,作者Christine和朋友Shannon回到了布莱尔高里小镇,与她们同行的还有Ian——一个友善风趣的英国小伙, | Christine Mc Cafferty | 2017 | 英语学习2017，0，10： | 0 |
| 18 | 摘水果的希望显示文摘由于发现了Ian的秘密赌局,Shannon开始疏远他并心生戒备。可迫于囊中羞涩,她们只得搭Ian的车赶往附近的一个农场,据说那里可以找到摘水果的工作。就在两人兴奋不已地盘算着能好好挣上一笔、 | Christine Mc Cafferty 李步 | 2017 | 英语学习2017，0，11： | 0 |
| 19 | 爱尔兰的男孩们显示文摘香依和克里斯汀,我们的两位背包客刚从遥远的爱尔兰西海岸回来,她们又冷又脏,浑身湿透。作为补偿,热情的东道主要给两人介绍英俊潇洒、风流倜傥的爱尔兰男孩!新的艳遇就在眼前,两人为此还特意去做了头发。结果如何?一起来看。 | Christine Mc Cafferty 李智镕 | 2018 | 英语学习2018，0，5： | 0 |
| 20 | 机车,文身与朋克显示文摘在卖海报的计划泡汤之后,作者和朋友搭车来到了阿伦岛,从泰瑞的口中她们了解到,阿伦岛是个宁静的地方,那里只有农民与零星的徒步旅行者。然而刚下车她们却被眼前的景象惊呆了:到处部是穿着奇装异服的人——机车手、朋克和嬉皮士……一场新的冒险即将开启。 | Christine Mc Cafferty | 2017 | 英语学习2017，0，8： | 0 |
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