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您的检索式：作者名="Chuchu Huang"
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| 1 | Ranking-Based Recommendation System with Text Modeling显示文摘In the study of recommendation systems,many methods based on predicting ratings have been put forward.However,the rating-predicting methods have some shortages.It pays too much attention to predicting,instead of the nature of recommendation,which is predicting the order of ratings.Thus,we use a pairwise-based learning algorithm to learn our model and take the zero-sampling method to improve our model.In addition,we propose a text modeling method making the recommendations more explicable.It is proved that our system performs better than other state-of-art | Chuchu Huang Guang Chen | 2015 | 国际计算机前沿大会会议论文集2015，，B12： | 0 |
| 2 | Tailored boron phosphate monolithic foam with multimodal hierarchically porous structure and its applications显示文摘The synthesis of multimodal hierarchically porous materials is of great challenge by facile approach.Herein,we assemble BPO_(4) hollow spheres into macroscopic foam materials with multimodal hierarchically porous structure by combining down-to-up process and Ostwald ripening effect.Tailored monolithic B_(2)O_(3)@BPO_(4) foams were obtained from a sticky hydrogel precursor by a one-step annealing process.The foam has the self-supporting frame of BPO_(4) hollow spheres with covering B_(2)O_(3) nanowires and shows excellent permeability and relatively high surface area due to hierarchical structure.The formation mechanism of monolithic B_(2)O_(3)@BPO_(4) foams mainly undergoes inflation,particle aggregation,and Ostwald ripening process.Monolithic foams exhibit superior catalytic activity in oxidation dehydrogenation of alkanes due to the sufficient exposure of active sites over the special frame structure.Furthermore,various monolithic functionalized BPO_(4) foam composites can be easily synthesized and exhibit superior performance in different applications including the oxidation of carbon monoxide,and the self-driven removal of organic pollutants.More interestingly,we also found the sticky hydrogel precursor possesses good heat shielding effect.This work provides a new insight for constructing multimodal hierarchically porous materials with the remaining superior property of nanoscale to cope with various challenges. | Qiuwen Liu Qiang Liu Yawei Wu Renyou Zeng Fangshu Xing ChuChu Cheng Huibin Qiu Caijin Huang | 2022 | Nano Research2022，15，7： | 0 |
| 3 | Biodegradable calcium sulfide-based nanomodulators for H_(2)S-boosted Ca^(2+)-involved synergistic cascade cancer therapy显示文摘Hydrogen sulfide(H_(2)S)is the most recently discovered gasotransmitter molecule that activates multiple intracellular signaling pathways and exerts concentration-dependent antitumor effect by interfering with mitochondrial respiration and inhibiting cellular ATP generation.Inspired by the fact that H_(2)S can also serve as a promoter for intracellular Ca^(2+)influx,tumor-specific nanomodulators(I-CaS@PP)have been constructed by encapsulating calcium sulfide(CaS)and indocyanine green(ICG)into methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide)(PLGA-PEG).I-CaS@PP can achieve tumor-specific biodegradability with high biocompatibility and pH-responsive H_(2)S release.The released H_(2)S can effectively suppress the catalase(CAT)activity and synergize with released Ca^(2+)to facilitate abnormal Ca^(2+)retention in cells,thus leading to mitochondria destruction and amplification of oxidative stress.Mitochondrial dysfunction further contributes to blocking ATP synthesis and downregulating heat shock proteins(HSPs)expression,which is beneficial to overcome the heat endurance of tumor cells and strengthen ICG-induced photothermal performance.Such a H_(2)S-boosted Ca^(2+)-involved tumor-specific therapy exhibits highly effective tumor inhibition effect with almost complete elimination within 14-day treatment,indicating the great prospect of CaS-based nanomodulators as antitumor therapeutics. | Chuchu Lin Chenyi Huang Zhaoqing Shi Meitong Ou Shengjie Sun Mian Yu Ting Chen Yunfei Yi Xiaoyuan Ji Feng Lv Meiying Wu Lin Mei | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 0 |
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