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3篇 您的检索式:作者名="Chuda CHITTASUPHO"
    题名 作者 年代 出处 被引量
1显示文摘Zhang Na Chittasupho Chuda Duangrat Chadarat ct a 2008Bioeonjugate Chem2008,19,1:1
2ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells 显示文摘Chuda Chittasupho Sheng-Xue Xie Abdulgader Baoum 2009European Journal of Pharmaceutical Sciences2009,37,:1
3Atractylodin-loaded PLGA nanoparticles:formulation and characterization显示文摘OBJECTIVE To formulate atractylodin-loaded poly(lactic-co-glycolic acid)(PLGA)nanoparticles and characterize the prepared nanoparticle formulation.METHODS The nanoparticle formulation was developed using solvent displacement method.The encapsulation and loading efficiency were characterized and particle size,and zeta potential were determined by dynamic light scattering technique.Drug release was assessed in vitro.RESULTS The size(mean±SD of diameter) of the prepared atractylodin-loaded PLGA nanoparticles were(161.27 ± 1.87)nm with narrow size distribution(mean PDI:0.068±0.015) and zeta potential(28.83±0.35)mV.The encapsulation and loading efficiency were(48.31±0.83)% and(2.15±0.04)%,respectively.Drug release from atractylodin-loaded PLGA nanoparticles was observed up to(87.70±0.47)% in 72 h with biphasic manner.Moreover,the nanoparticles were found to be freely dispersible in water without aggregation.CONCLUSION Results suggest that PLGA nanoparticles may be used as an effective drug delivery system for atractylodin.The anti-cholangiocarcinoma activity of this nanoparticle formulation is required.Nadda MUHAMAD Tullayakorn PLENGSURIYAKARN Chuda CHITTASUPHO Kesara NA-BANGCHANG 2018中国药理学与毒理学杂志2018,32,4:0
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