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20篇 您的检索式:作者名="Ciofini"
    题名 作者 年代 出处 被引量
1Endothelial function and carotid intimal media thickness in young healthy subjects among endothelial nitric oxide synthase Glu298-Asp and T786C polymorphisms显示文摘PARODOSSI U CIOFINI E CLERICO A 2004Stroke2004,35,:1
2Efficiency optimization for a diode-pumped Nd:YAG ceramic slab laser显示文摘LAPUCCI A CIOFINI M 2005Applied Optics2005,44,20:1
3Controlling quasiperiodieity in a CO2 laser with delayed feedback显示文摘Labate A Ciofini M Meueei R 1998Phys Rev E1998,57,5:1
4Experimental control of chaos by means of weak parametric perturbations 显示文摘Mcucci R Gadomski W Ciofini M 1994Phys Rcv E1994,49,:1
5The control of chaos: theoretical schemes and experimental realizations显示文摘Arechi F T Boccaletti S Ciofini M 1998Int J Bifurcation & Chaos1998,8,8:1
6Stabilization of unstable fixed points in the dynamics of a laser with feedback显示文摘CIOFINI M LABATE A MEUCCI R 1999Physics Review E1999,60,1:1
7显示文摘CIOFINI I LAINE P P BEDIOUI F 2006Comptes Rendus Chimie2006,9,22:1
8Photoinducedprocesses within compact dyads based on triphenylpyri-dinium-functionalized bipyridyl complexes of ruthenium(11)显示文摘Laine P P Ciofini I Ochsenbein P 2005Chemistry-A European Journal2005,11,:1
9Photoinduced Intramolecular Electron Transfer in Ruthenium and Osmium Polyads:Insights from Theory显示文摘Ciofini I Laine P P Bedioui F 2004J Am Chem Soc2004,126,10:1
10显示文摘JACQUEMIN D PEROTEE A CIOFINI L 2009Acc Chem Res2009,42,2:1
11Effective Two-dimensional Model for CO2 Lasers 显示文摘Ciofini M Politi A Meucci R 1993Phys Rev A1993,48,:1
12Propagation parameters of the beam extracted from a diode pumped Nd: YAG ceramic slab laser with a hybrid stable-unstable resonator显示文摘CIOFINI M FAVILLA E LAPUCCI A 2007Optics & Laser Technology2007,39,7:1
13Drug resistance and minimal residual disease in multiple myeloma显示文摘Great progress has been made in improving survival in multiple myeloma(MM)patients over the last 30 years.New drugs have been introduced and complete responses are frequently seen.However,the majority of MM patients do experience a relapse at a variable time after treatment,and ultimately the disease becomes drug-resistant following therapies.Recently,minimal residual disease(MRD)detection has been introduced in clinical trials utilizing novel therapeutic agents to measure the depth of response.MRD can be considered as a surrogate for both progression-free and overall survival.In this perspective,the persistence of a residual therapy-resistant myeloma plasma cell clone can be associated with inferior survivals.The present review gives an overview of drug resistance in MM,i.e.,mutation ofβ5 subunit of the proteasome;upregulation of pumps of efflux;heat shock protein induction for proteasome inhibitors;downregulation of CRBN expression;deregulation of IRF4 expression;mutation of CRBN,IKZF1,and IKZF3 for immunomodulatory drugs and decreased target expression;complement protein increase;sBCMA increase;and BCMA down expression for monoclonal antibodies.Multicolor flow cytometry,or next-generation flow,and next-generation sequencing are currently the techniques available to measure MRD with sensitivity at 10-5.Sustained MRD negativity is related to prolonged survival,and it is evaluated in all recent clinical trials as a surrogate of drug efficacy.Alessandro Gozzetti Sara Ciofini Anna Sicuranza Paola Pacelli Donatella Raspadori Emanuele Cencini Dania Tocci Monica Bocchia 2022Cancer Drug Resistance2022,5,1:1
14Extraction of high-quality beams from narrow annular laser sources显示文摘Lapucci A Ciofini M 1999Appl Opt1999,35,21:1
15查看详情显示文摘Ciofini I Laine P P Bedioui F Adamo C 0,,34:1
16First principles modeling of eosin-loaded ZnO films: a step toward the understanding of dye-sensitized solar cell performances显示文摘LABAT F CIOFINI I HRATCHIAN H P 2009J Am Chern Soc2009,131,14:1
17The control of chaos:theoretic schemes and experimental realization显示文摘Arecchi F T Boccaletti S Ciofini M 1998Int J Bifurcation&Chaos1998,8,8:1
18Theoretical modelling of photoactive molecular systems:insights using the Density Functional Theory显示文摘Ciofini I Lainé P P Bedioui F 2006Comptes Rendus Chimie2006,,9:1
19Red-emitting tetraphenylethylene derivative with aggregation-induced enhanced emission for luminescent solar concentrators:A combined experimental and density functional theory study显示文摘This study examines the use of an aggregation-induced enhanced emission fluorophore(TPE-MRh)to prepare red-emitting luminescent solar concentrators(LSCs)based on poly(methyl methacrylate)(PMMA)and poly(cyclohexyl methacrylate)(PCMA).TPE-MRh is a tetraphenylethylene(TPE)derivative bearing two dimethylamino push groups and a 3-methyl-rhodanine pull moiety,with absorption maxima at around 500 nm and fluorescence peak at 700 nm that strongly increases in solid-state.TPE-MRh displays a typical crystallizationinduced enhanced emission that has been rationalized by modeling the compound behavior in solution and solid-state via density functional theory calculations with the inclusion of the environment.TPE-MRh dispersed into 5×5 cm2 polymer films with a thickness of 25±5μm has revealed a partial fluorescence quenching with fluorophore content.Quantum yields(QYs)below 10%for the 2 wt.%of doping have been addressed to the formation of less emissive micro-sized clusters of fluorophores.PMMA slabs with the same surface size but 3 mm of thickness and 200 ppm of TPE-MRh have provided QY of 36.5%thanks to the attenuation of the detrimental effects of fluorophore aggregation.This feature is reflected in the LSCs performance,with devices achieving the largest power collected by the photovoltaic cell.Cosimo Micheletti Qinfan Wang Francesco Ventura Michele Turelli Ilaria Ciofini Carlo Adamo Andrea Pucci 2022Aggregate2022,3,2:0
20Anti-BCMA novel therapies for multiple myeloma显示文摘Recent advances in multiple myeloma therapy have increased the depth of response and ultimately survivals;however,the prognosis remains poor.The BCMA antigen is highly expressed in myeloma cells,thus representing a target for novel therapies.Several agents that target BCMA through different mechanisms,including bispecific T cell engagers drug conjugated to antibody and CAR-T cells,are now available or under development.Immunotherapies targeting BCMA have shown good results in efficacy and safety in multiple myeloma patients previously treated with several lines of therapy.This review will discuss the recent development of anti-BCMA targeted treatments in myeloma,with a special focus on currently available agents.Vincenzo Sammartano Marta Franceschini Sara Fredducci Federico Caroni Sara Ciofini Paola Pacelli Monica Bocchia Alessandro Gozzetti 2023Cancer Drug Resistance2023,6,1:0
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