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5篇 您的检索式:作者名="Clara NERVI"
    题名 作者 年代 出处 被引量
1Dynamic and reversibility of heterochromatic gene silencing in human dis-ease显示文摘In eukaryotic organisms cellular fate and tissue specific gene expression are regulated by the activity of proteins known as transcription factors that by interacting with specific DNA sequences direct the activation or repression of target genes. The post genomic era has shown that transcription factors are not the unique key regulators of gene expression. Epigenetic mechanisms such as DNA methylation, post-translational modifications of histone proteins, remodeling of nucleosomes and expression of small regulatory RNAs also contribute to regulation of gene expression, determination of cell and tissue specificity and assurance of inheritance of gene expression levels. The relevant contri- bution of epigenetic mechanisms to a proper cellular function is highlighted by the effects of their deregulation that cooperate with genetic alterations to the development of various diseases and to the establishment and progression of tumors.Giuseppe ZARDO Francesco FAZI Lorena TRAVAGLINI Clara NERVI 2005Cell Research2005,15,9:5
2Retinoic acid receptors and cancer: from molecular mechanisms to therapy显示文摘Alessandra di Masi Loris Leboffe Elisabetta De Marinis Francesca Pagano Laura Cicconi Cécile Rochette-Egly Francesco Lo Coco Paolo Ascenzi Clara Nervi 2014Molecular Aspects of Medicine2014,,:2
3Epigenetic Silencing of the Myelopoiesis Regulator microRNA-223 by the AML1/ETO Oncoprotein显示文摘Francesco Fazi Serena Racanicchi Giuseppe Zardo Linda M. Starnes Marco Mancini Lorena Travaglini Daniela Diverio Emanuele Ammatuna Giuseppe Cimino Francesco Lo-Coco Francesco Grignani Clara Nervi 2007Cancer Cell2007,,:1
4Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity 显示文摘Clara Nervi Ugo Borello Francesco Fazi 2001Cancer Research2001,61,:1
5A Minicircuitry Comprised of MicroRNA-223 and Transcription Factors NFI-A and C/EBPα Regulates Human Granulopoiesis显示文摘Francesco Fazi Alessandro Rosa Alessandro Fatica Vania Gelmetti Maria Laura De Marchis Clara Nervi Irene Bozzoni 2005Cell2005,,5:1
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