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408篇 您的检索式:作者名="Claussen"
    题名 作者 年代 出处 被引量
1Application of poly-lactide-co-glycolide-microspheres in the transarterial chemoembolization in an animal model of hepatocellular carcinoma显示文摘AIM:To introduce an animal model of hepatocellular carcinoma (HCC) in ACI-rats, and to evaluate the therapeutic effects of Poly-lactide-co-glycolide(PIcg)-microspheres in the transarterial chemoembolization (TACE) in this model, as well the value of this model in the experiments of interventional therapy.Jochen Truebenbach Florian Graepler Philippe Pereira Peter Huppert Thomas Eul Gundula Wiemann Claus Claussen 2003World Journal of Gastroenterology2003,9,1:24
2Liver fat content determined by magnetic resonance imaging and spectroscopy显示文摘Hepatic steatosis as the most prevalent liver disorder can either be related to alcoholic liver disease (ALD) or non-alcoholic fatty liver disease (NAFLD). In both conditions, hepatocytes excessively accumulate fatcontaining vacuoles within their cytoplasm, which is the key histological feature. In contrast to ALD, NAFLD is commonly associated with metabolic syndrome, obesity and insulin resistance. To determine increased liver fat content, liver biopsy is currently considered the gold standard. Besides the invasive technique, various other non-invasive techniques have been developed, such as ultrasound, computed tomography (CT), magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) based methods. Among these techniques, ultrasound and CT provide only qualitative information about hepatic steatosis, whereas MRS-or MRI-based methods are able to determine even small amounts of fat accurately. These non-invasive magnetic resonance techniques have already proven their great potential, especially in longitudinal and cross-sectional studies regarding various metabolic conditions and medical treatment regimens. In this review, the most common, non-invasive MRS/MRI techniques for assessment of intrahepatic lipid content are described with their inherent advantages and limitations.Fabian Springer Jürgen Machann Claus D Claussen Fritz Schick Nina F Schwenzer 2010World Journal of Gastroenterology2010,16,13:19
3同种移植大鼠肝细胞癌模型的建立及其磁共振表现显示文摘目的 采取同种移植技术 ,在ACI大鼠建立 1种理想的、适合于介入治疗和MRI观察的肝细胞癌模型。方法 在 1只雄性ACI大鼠背部皮下注射MorrisHepatoma 392 4A肝癌细胞。 13d后从生长的肿瘤中切取 1mm3 瘤块移植到另外的雄性ACI大鼠左肝包膜下 (共 12只 ) ,移植术后 14d利用MRI观察肿瘤体积及其特征 ,并取肿瘤标本做病理切片检查。结果 移植术后 14d时 ,MR检查见所有ACI大鼠肝内均长出孤立性结节状肿瘤 ,不伴有转移和腹水 ,肿瘤平均体积为 (0 .0 90±0 .0 0 8)cm3 。在所有被移植大鼠中 ,病灶在T1WI上呈低信号 ,在T2 WI上呈高信号。病理切片检查示肿瘤内无明显坏死和出血 ,其周围血管丰富。结论 该种建立肝细胞癌动物模型的方法操作简便 ,易于重复 ,移植成功率高 ,肿瘤生长速度适宜 ,无转移和腹水 ,MR检查效果良好 ,尤其适于肝癌介入治疗的研究。钱骏 冯敢生 Truebenbach Jochen Pereira Philippe Huppert Peter Claussen Claus 2002中华放射学杂志2002,36,5:15
4树莓派4:全新的背后,依然是优秀的表现吗?显示文摘引言全新的树莓派(Pi)4终于发布了!树莓派4的发布带来了许多我们期待已久的变化,现在就让我们亲自来对新的硬件进行测评,并总结第一印象。在此之前,树莓派每代的变化都不太大。树莓派2到3是一次不错的更新,但是树莓派3 B+相对3B而言就仅仅是外观上有些变化。树莓派3 B+发布之后,其他竞争者发布了更加强大且功能丰富的硬件,比如包含USB 3.0和原生以太网。在尽可能保持和以往外形相似的前提下,新的树莓派4不得不在硬件上有所创新。图1和图2展示了硬件的细节,在介绍完硬件之后我们会介绍软件。Mathias Claussen 禾沐(译) 2020单片机与嵌入式系统应用2020,20,6:8
5ACI大鼠肝细胞癌模型在介入治疗实验中的初步应用显示文摘目的 评价在ACI大鼠肝细胞癌模型进行多种介入治疗方案的疗效及该模型在介入治疗实验中的应用价值。方法 在 5 8只雄性ACI大鼠肝包膜下植入MorrisHepatoma 3 92 4A肝癌瘤块( 1mm3) ,移植术后 13d行MR检查 ,测量肿瘤体积 (V1) ,第 14天时 ,经腹部切开术及胃十二指肠动脉逆行插管而采取以下介入治疗方案 :(A)丝裂霉素 4只 ;(B)降解淀粉 4只 ;(C)碘油 5只 ;(D)肝动脉结扎 4只 ;(E)丝裂霉素 +降解淀粉 4只 ;(F)丝裂霉素 +动脉结扎 5只 ;(G)丝裂霉素 +碘油 5只 ;(H)降解淀粉 +动脉结扎 4只 ;(I)碘油 +动脉结扎 4只 ;(J)丝裂霉素 +聚丙交酯复合乙交酯 (poly lactid co glycolid ,Plcg)微球 4只 ;(K)丝裂霉素 +碘油 +动脉结扎 4只 ;(L)丝裂霉素 +降解淀粉 +动脉结扎4只 ;(M) 0 9%生理盐水 (对照组 ,7只 )。 13d后再次行磁共振检查以确定肿瘤体积 (V2 )变化 ,并对各组间V2 /V1的比值进行比较。结果 肝癌移植率为 10 0 %。介入治疗后肿瘤体积与治疗前肿瘤体积之比 (V2 /V1)分别为A组 4 5 0 ,B组 12 73 ,C组 15 84,D组 10 17,E组 90 2 0 ,F组 7 16,G组 4 0 8,H组 3 45 ,I组 9 99,J组 2 86,K组 3 76,L组 7 71,M组 2 7 12。与对照组相比 ,采取A、G、H、J和K组方法能明显抑制肿瘤生长 ( χ2 值分别为 5钱骏 Truebenbach Jochen Eul Thomas Graepler Florian Pereira Philippe Huppert Peter 冯敢生 Claussen Claus 2003中华放射学杂志2003,37,1:5
6聚丙交酯复合乙交酯微球经肝动脉化疗栓塞术治疗肝癌的动物实验显示文摘目的 :在肝细胞癌动物模型上观察聚丙交酯复合乙交酯 (PLcG)微球经肝动脉化疗栓塞术 (TACE)治疗肝癌的疗效。方法 :在雄性ACI大鼠 ( 15例 )肝包膜下植入MorrisHepatoma 392 4A肝癌小瘤块 ( 1mm3) ,移植术后 13天时行磁共振检查。再经正中腹切开术和经胃十二指肠动脉逆行插管进行以下介入治疗 :治疗组A( 40mgPLcG + 0 .0 5mg丝裂霉素 ,4例 )、对照组B( 0 .0 5mg丝裂霉素 + 0 .0 4mg碘化油 +肝动脉结扎 ,4例 )和对照组C( 1.5ml生理盐水 ,7例 )。插管术后 13天再次行磁共振术观察肝肿瘤体积变化。结果 :在C组 ,肿瘤体积在实验期间增长 2 7.12倍 ,在B组 ,肿瘤体积增长 3.76倍 ,而在A组 ,肿瘤体积仅增长 2 .87倍。A组与C组肿瘤体积增长率在t检验时均有显著性差异 (P <0 .0 5 )。结论 :在动物实验中将PLcG微球运用于TACE可明显抑制肝肿瘤生长。钱骏 冯敢生 TruebenbachJ Pereira PL Huppert PE Graepler F Eul T Claussen CD 2001放射学实践2001,16,6:4
7Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography 1 1 This study was performed without additional financial support.显示文摘Stephen Schroeder Andreas F Kopp Andreas Baumbach Christoph Meisner Axel Kuettner Christian Georg Bernd Ohnesorge Christian Herdeg Claus D Claussen Karl R Karsch 2001Journal of the American College of Cardiology2001,,5:3
8Fracture toughness of Al2O3 with an unstabilized ZrO2 dispersed phase 显示文摘Claussen N 1976J Am Ceram Soc1976,59,1:3
9MQTT传感器中枢——使用ESP32 PICO KIT读取和传输传感器数值显示文摘我们在最近一期中发布的一个项目是Monster LED钟,它有一个很大的七段显示器(见图1)。这个显示器不仅可以显示一天的时间,还可以显示通过MQTT从无线网络接收的传感器数值。在本文中,我们将介绍其他一些可将传感器直接连接到ESP32上的固件。数据使用MQTT发送到中央代理器。中央代理器可以使用一个运行Mosquitto和Node RED的Raspberry Pi来实现。Mathias Claussen 禾沐 2020单片机与嵌入式系统应用2020,20,2:2
10Influence of heart rate on vessel visibility in noninvasive coronary angiography using new multislice computed tomography显示文摘Stephen Schroeder Andreas F Kopp Axel Kuettner Christof Burgstahler Christian Herdeg Martin Heuschmid Andreas Baumbach Claus D Claussen Karl R Karsch Ludger Seipel 2002Clinical Imaging2002,,2:2
11Genotypic differences in the heat-shock response and thermotolerance in four potato cultivars 显示文摘Ahn Y J Claussen K Zimmerman J L 2004Plant Science2004,166,4:1
12Whole-body low -dose multi-detector row-CT in the diagnosis of multiple myeloma:an alternative to conventional radiograph显示文摘Horger M Claussen CD Bross-Bach U 2005Eur J Radiol2005,54,2:1
13Auxin induced growth and its link- age to potassium channels显示文摘Claussen M Luthen H Borer M 1997Planta1997,201,:1
14Fracture toughness of Al2O3 with an unstabilized ZrO2 dispersed phase显示文摘CLAUSSEN N 1976J Am Ceram Soc1976,59,:1
15Very early indicators of response to systemic therapy in lymphoma patients based on alterations in water diffusivity: a preliminary experience in 20 patients undergoing whole-body diffusion-weighted imaging显示文摘Horger M Claussen C Kramer U 2014Eur J Radiol2014,83,9:1
16Effect of ammonium or nitrate nutrition on net photosynthesis, growth, and activity of the enzymes nitrate reductase and glutamine synthetase in blueberry, raspberry and strawberry显示文摘W. Claussen F. Lenz 1999Plant and Soil1999,,1:1
17Femtocells: past, present, and future显示文摘Andrews J G Claussen H Dohler M 2012IEEE Journal on Selected Areas in Communications2012,30,3:1
18Strength and fracture toughness of aluminum/alumina composites with interpenetrating networks显示文摘PRIELIPP H KNECHTEL M CLAUSSEN N el al 1995Materials Science and Engineering: A1995,197,1:1
19Exploiting early sorting and early partitioning for decision support query processing显示文摘Claussen J Kemper A Kossmann D 2000The VLDB Journal2000,9,3:1
20Bolus geometry and dynamics after intravenous contrast medium injection 显示文摘Claussen CD BanzerD Pfretzschner C 1984Radiology1984,153,:1
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