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| 1 | The roles of MAPKs in disease显示文摘印射响应许多 ligands 和房间刺激涉及大量的细胞的小径和功能的家族 ases transduce 信号。MAPK 的异常或不恰当的功能现在在从癌症到煽动性的疾病到肥胖和糖尿病的疾病被识别了。在许多房间类型, MAPK ERK1/2 被连接到细胞增殖。因为在地岬和 B-Raf 的变化,能激活 ERK1/2 串联,在许多人的肿瘤被发现, ERK1/2 被认为在一些癌症起一个作用。发信号的反常 ERK1/2 也在 polycystic 肾疾病被发现了,并且象 cardio-facio-cutaneous 症候群那样的严肃的发展混乱在 ERK1/2 串联的部件从变化产生。ERK1/2 在区分得好的房间是必要的并且在神经原并且在上皮的极性的维护被连接了到长期的 potentiation。另外, ERK1/2 为在胰腺的贝它房间的胰岛素基因抄写是重要的,它响应传播葡萄糖的增加生产胰岛素在有机体允许有效葡萄糖利用和存储。导致或镇压的营养素和荷尔蒙胰岛素分泌物以在贝它房间上反映能分泌的需求的一种方式激活或禁止 ERK1/2。在这和另外的规章的小径的骚乱可以导致对某些人的混乱的病原学的 ERK1/2 的贡献。 | Michael C Lawrence Arif Jivan Chunli Shao Lingling Duan Daryl Goad Elma Zaganjor Jihan Osborne Kathleen McGlynn Steve Stippec Svetlana Earnest Wei Chen Melanie H Cobb | 2008 | Cell Research2008，18，4： | 64 |
| 2 | Vascular endothelial growthfactorexprassion in transient focal cerebral ischemia in the rat显示文摘 | Cobbs C S Chen J Grennberg D A | 1998 | Neurosci-lett1998，，： | 1 |
| 3 | A theory of production 显示文摘 | Cobb C W Douglas P H | 1928 | American Economic Review1928，，1： | 1 |
| 4 | Improved bone-forming functionality on diame- ter-controlled Ti02 nanotube surface显示文摘 | Brammer K S Oh S Cobb C J Bjursten L M Heyde H Jin S | 2009 | Acta Biomate- rialia2009，5，8： | 1 |
| 5 | Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates显示文摘 | Devine SM Cobbs C Jennings M | 2003 | Blood2003，101，8： | 1 |
| 6 | Decomposition of green foliage in eastern hemlock forests of southern New England impacted by hem- lock woolly adelgid infestations 显示文摘 | Cobb R C Orwig D A Currie S | 2006 | Canadian Journal of Forest Re- search2006，36，： | 1 |
| 7 | US characteristics of fro zen prostate显示文摘 | ONIK G COBB C COHEN J | 1988 | Radiology1988，168，3： | 1 |
| 8 | A theory of production显示文摘 | COBB C W DOUGLAS P H | 1928 | American E- conomic Review1928，，18： | 1 |
| 9 | The Impact of B-type Natriuretic Peptide,New York Heart Association Classification and Depression on Quality of Life in Nonhospitalized Heart Failure Patients显示文摘 | Ancheta IB Battie C Cobb S | 2009 | Prog Cardiovasc Nurs2009，24，4： | 1 |
| 10 | Nonlethal Method for Forensic Evaluation of Adducer Exposure 显示文摘 | Cobb G P Harper F D Weisskopf C P | 2001 | Environ Contain Toxicol2001，40，： | 1 |
| 11 | Global finance and the growth of offshore fi- nancial centers: the Manx experience 显示文摘 | Cobb S C | 1998 | Geoforum1998，29，1： | 1 |
| 12 | Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates显示文摘 | DEVINE SM COBBS C JENNINGS M | 2003 | Blood2003，101，8： | 1 |
| 13 | Normalizing- Hip Muscle Strength: Establishing Body - Size - Independent Measurements显示文摘 | Bazett- Jones D M Cobb S C Joshi M N | 2011 | Archives of Physical Medicine and Rehabili- tation2011，92，1： | 1 |
| 14 | Comparison of femoral bleeding complications after coronary angiography versus percutane- ous coronary intervention显示文摘 | Berry C Kelly J Cobbe SM | 2004 | Am J Cardiol2004，94，3： | 1 |
| 15 | A Theory of Production显示文摘 | COBB C W DOUGLAS P H | 1928 | The American Economic Review1928，，： | 1 |
| 16 | Does Mind No Longer Matter? The South, the Nation, and The Mind of the South,1941-1991显示文摘 | COBB James C | 1991 | The Journal of Southern History1991，57，4： | 1 |
| 17 | Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates 显示文摘 | Devine SM Cobbs C Jennings M | 2003 | Blood2003，101，8： | 1 |
| 18 | Comparison of femoral bleeding complications after coronary angiography versus percutaneous coronary intervention 显示文摘 | Berry C Kelly J Cobbe SM | 2004 | Am J Cardiol2004，94，4： | 1 |
| 19 | A multiobjective evolutionary conceptual clustering methodology for gene annotation within structural databases:A case of study on the gene ontology database显示文摘 | Romero-Zaliz R C Rubio-Escudero C Cobb J P | 2008 | IEEE Transactions on Evolutionary Computation2008，12，6： | 1 |
| 20 | Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates 显示文摘 | Devine SM Cobbs C Jennings M | 2003 | Blood2003，101，8： | 1 |
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