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3篇 您的检索式:作者名="Colin Bishop"
    题名 作者 年代 出处 被引量
1SNL fibroblast feeder layers support derivation and maintenance of human induced pluripotent stem cells显示文摘Induced pluripotent stem(iPS) cells can be derived from human somatic cells by cellular reprogramming.This technology provides a potential source of non-controversial therapeutic cells for tissue repair,drug discovery,and opportunities for studying the molecular basis of human disease.Normally,mouse embryonic fibroblasts(MEFs) are used as feeder layers in the initial derivation of iPS lines.The purpose of this study was to determine whether SNL fibroblasts can be used to support the growth of human iPS cells reprogrammed from somatic cells using lentiviral expressed reprogramming factors.In our study,iPS cells expressed common pluripotency markers,displayed human embryonic stem cells(hESCs) morphology and unmethylated promoters of NANOG and OCT4.These data demonstrate that SNL feeder cells can support the derivation and maintenance of human iPS cells.Chuanying Pan Amy Hicks Xuan Guan Hong Chen Colin E. Bishop 2010Journal of Genetics and Genomics2010,37,4:5
2The Structure of the Y Chromosome and Its Role in Male Infertility显示文摘Leslie Ayensu-Coker Colin Bishop Jan Rohozinski 2007The Genetics of Male Infertility2007,,:1
3Oxidative stress is involved in age- dependent spermatogenic damage of immp 21 mu- tant mice显示文摘George Sunil K George Yah Jiao Colin E Bishop 2012Free Radic Biol Med2012,52,1112:1
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