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3篇 您的检索式:作者名="Colin H Wilson"
    题名 作者 年代 出处 被引量
1Biodegradable stent or balloon dilatation for benign oesophageal stricture: Pilot randomised controlled trial显示文摘AIM:To undertake a randomised pilot study comparing biodegradable stents and endoscopic dilatation in patients with strictures.METHODS:This British multi-site study recruitedseventeen symptomatic adult patients with refractory strictures.Patients were randomisedus in gamulticentre,blinded assessor design,comparing a biodegradable stent(BS)with endoscopic dilatation(ED).The primary endpoint was the average dysphagia score during the first 6 mo.Secondary endpoints included repeat endoscopic procedures,quality of life,and adverse events.Secondary analysis included follow-up to 12 mo.Sensitivity analyses explored alternative estimation methods for dysphagia and multiple imputation of missing values.Nonparametric tests were used.RESULTS:Although both groups improved,the average dysphagia scores for patients receiving stents were higher after 6 mo:BS-ED 1.17(95%CI:0.63-1.78)P=0.029.The finding was robust under different estimation methods.Use of additional endoscopic procedures and quality of life(QALY)estimates were similar for BS and ED patients at 6 and12 mo.Concomitant use of gastrointestinal prescribed medication was greater in the stent group(BS 5.1,ED 2.0 prescriptions;P<0.001),as were related adverse events(BS 1.4,ED 0.0 events;P=0.024).Groups were comparable at baseline and findings were statistically significant but numbers were small due to under-recruitment.The oesophageal tract has somatic sensitivity and the process of the stent dissolving,possibly unevenly,might promote discomfort or reflux.CONCLUSION:Stenting was associated with greater dysphgia,co-medication and adverse events.Rigorously conducted and adequately powered trials are needed before widespread adoption of this technology.Anjan Dhar Helen Close Yirupaiahgari K Viswanath Colin J Rees Helen C Hancock A Deepak Dwarakanath Rebecca H Maier Douglas Wilson James M Mason 2014World Journal of Gastroenterology2014,20,48:1
2Evaluation of eight preservation solutions for endothelial in situ preservation 显示文摘WILSON COLIN H STANSBY J Surg Res0,78,7:1
3Review of abdominal solid organ transplantation in Jehovah’s Witness patients显示文摘Managing blood loss in Jehovah’s Witness(JW)patients is a matter of controversy.These patients will not accept transfusions of red blood cells,white blood cells,platelets or plasma,even if that is required to save their lives.There are many discussions regarding safety of operating upon JW patients in general surgical procedures,but in solid organ transplantation there is a paucity of literature on this subject.We have reviewed individual case reports and small series documenting on experience with solid organ transplantation in JW patients and the strategies adopted to facilitate that.It is clear that such patients require the surgical team to dedicate more time to ensure their safe management.This begins with a thorough,detailed consent of exactly which products and interventions they will or will not accept.Planning must begin weeks before surgery if possible.Each case must be assessed individually,but provided they meet fitness requirements,there are no absolute contraindications to abdominal organ transplantation.Rodrigo S Figueiredo Rohan G Thakkar Paul R Ainley Colin H Wilson 2019World Journal of Transplantation2019,9,5:0
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