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| 1 | Nanoscalezerovalent iron alters soil bacterial community structure and inhibits chloroaromatic biodegradation potential in Aroclor 1242-contaminated soil 显示文摘 | Tilston EL Collins CD Mitchell GR | 2013 | Environ Pollut2013，173，： | 1 |
| 2 | Inhibition ofSOCS1 lethal autoinflammatory disease correlated toenhanced peripheral Foxp3 + regulatory T cell homeostasis显示文摘 | Collins EL Jager LD Dabelic R | 2011 | J Immunol2011，187，5： | 1 |
| 3 | Distribution and origin of secretoneurin-immunoreactive nerves in the female rat uterus显示文摘 | Collins J J Wilson K Fischer-Colbrie R el al | 2000 | Neuroscience2000，95，1： | 1 |
| 4 | Quercetin and myricetin protect against hydrogen peroxide-induced DNA damage (strand breaks and oxidized pyrimidines)in human lymphocytes显示文摘 | Duthie S J Collins A R Duthie G C el al | 1997 | Mutat Res1997，393，： | 1 |
| 5 | In vitro antimicrobial activities of capuramycin analogues against non-tuberculous mycobacteria 显示文摘 | Dubuisson T Bogatcheva El Krishnan MY Collins MT Einck L Nacy CA Reddy VM | 2010 | J Antimicrob Chemother2010，65，12： | 1 |
| 6 | Inhibition of SOCSI -/- lethal autoinflammatory disease correlated to enhanced peripheral Foxp3 + regulatory T cell homeostasis 显示文摘 | Collins EL Jager LD Dabelic R | 2011 | J Immunol2011，187，5： | 1 |
| 7 | Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial显示文摘 | Robins S J Collins D Wittes JT el al | 2001 | JAMA2001，285，12： | 1 |
| 8 | Vascular endothelia| growth factor and basic fibroblast growth factor and found in resolving venous thrombi显示文摘 | Waltham M Bumand KG Collins M el al | 2000 | J Vasc Surg2000，32，5： | 1 |
| 9 | Androgen and oestro- gen responsiveness of strom',d cells derived from the human hyper- platie prostate : oestrogen regulation of the androgen receptor显示文摘 | Collins AT Zhiming B Gilmore K el al | 1994 | J Endocrinol1994，143，2： | 1 |
| 10 | Improved re- sponse of plaque psoriasis after multiple treatments with topical 5-aminolae-vulinic acid photodynamic ther- apy340 显示文摘 | Robinson D J Collins P Stringer MR el al | 1999 | Acta Dermato-Venereol1999，79，： | 1 |
| 11 | Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis显示文摘 | Chan EL Peace BE Collins MH | | 0，，03： | 1 |
| 12 | Eotaxin: a potent eosinophii chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation显示文摘 | Jose PJ Griffiths - Johnson DA Collins PD el ai | 1994 | J Exp Med1994，1791，： | 1 |
| 13 | Natural history of cervical human papillomavirus infection in young women:longitudinal cohorts study 显示文摘 | Woodman CB Collins S Winter H el al | 2001 | Lancet2001，357，： | 1 |
| 14 | A new surgical education and training programme显示文摘 | Collins JP Gough IR Civil ID el al | 2007 | Ausl NZ J Surg2007，77，： | 1 |
| 15 | Effects of raloxifene oncardiovascular events and breast cancer in postmenopausal womcn显示文摘 | Barrett-Connor E Mosca L Collins P el al | 2006 | NEngl J Med2006，355，2： | 1 |
| 16 | Mutations in C2ORF71 cause autosomal recessive retinitis pigmenlosa 显示文摘 | Collin RW Safieh C Littink KW el al | 2010 | Am J Hure C-enet2010，86，8： | 1 |
| 17 | Effects of different feed additives alone or in combination on broiler performance,gut microflora and ileal histology 显示文摘 | Owens B Tucker L Collins M A et el | 2008 | British Poultry Science2008，49，2： | 1 |
| 18 | Peripheral arterial dis- ease is associated with higher rates of hip bone loss and in- creased fracture risk in older men显示文摘 | Collins TC Ewing SK Diem SJ el at | 2009 | Circulation2009，119，17： | 1 |
| 19 | Plant community responses to resource availability and heterogeneity during rostoration显示文摘 | Baer SG Blair J M Collins S L el al | 2004 | Oecologia2004，139，4： | 1 |
| 20 | LC-MS Identification and Preliminary Pharmacological Study of the Aqueous and Ethanol Extracts from Combretum glutinosum Perr ex DC.(Combretaceae)显示文摘Background:Combretum glutinosum is a plant whose leaves are consumed as a vegetable and used in traditional medicine for the treatment of microbial infections.Objective:The present study was designed to identify the compounds in C.glutinosum leaves extracts,and evaluate its antimicrobial activity,antioxidant ability and its toxicity in Artemia salina larvae in vitro.Methods:The aqueous and ethanol extracts obtained from the leaves of the plant as well as known compounds previously isolated and characterized from the leaves of C.glutinosum were tested on eleven different microbial strains.The antioxidant activity of the extracts was evaluated by the Ferric Reducing Antioxidant Power method and the larval toxicity on Artemia salina larvae was also detected.Phytochemical screening and HPLC-DAD-HRESI-MS analysis were performed on the extracts to characterize its chemical composition.Results:When tested at a concentration of 20 mg‧mL^(−1),the extracts of C.glutinosum leaves strongly inhibited the growth of the bacterial strains with an inhibition diameter ranging from 7.25 mm to 44 mm,superior to those of the positive controls(tetracycline at 30μg‧mL^(−1)and amikacin at 30μg‧mL^(−1)),inhibition diameters from 15 mm to 33 mm.The evaluated larval toxicity demonstrated that it had no harmful effects on Artemia salina larvae.The extracts present a good antioxidant activity at a concentration of 0.17 and 1.33 mmol ascorbic acid(per gram of extract)for the aqueous and ethanol extracts,respectively.However,none of the compounds tested at 500μg‧mL^(−1)were able to show good activity on the 11 reference strains.Phytochemical analysis revealed the presence of alkaloids,polyphenols,steroids,triterpenoids,reducing compounds,etc.in both extracts.The HPLC-DAD-HRESI-MS analyses revealed 18 compounds in the ethanol extract,from which 3 were identified,15 compounds in the aqueous extract from which 5 could be identified.Conclusion:The present work has shown that C.glutinosum extracts can be a good source of antimicrobial agents.They also possess the antioxidant property with absence of toxicity on A.salina larvae.A further bio-guided study could allow the identification and isolation of the active ingredients. | Placide Mahougnan Toklo Mathias Amour Ahomadegbe Durand Dah-Nouvlessounon Jean-Bosco Jouda Billy Toussie Tchegnitegni Steven Collins Njonte Wouamba Djidénou Ahoton Mahoudo Fidèle Assogba Joseph Tchamgoue Bruno Ndjakou Lenta Simeon Fogue Kouam Lamine Baba-Moussa Eléonore Chikani Yayi Ladekan Joachim Djimon Gbenou | 2023 | Clinical Complementary Medicine and Pharmacology2023，3，4： | 0 |
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