维普中文期刊产品整合服务
12篇 您的检索式:作者名="Congar"
    题名 作者 年代 出处 被引量
1Postsynaptic injection of calcium-independent phospholipase A2 inhibitors selectively increases AMPA receptor-mediated synaptic transmission 显示文摘St-Gelais F Menard C Congar P 2004Hippocampus2004,14,3:1
2Hippocampal CA1 lacu no- sum-moleculare interneurons: comparison of effects of anoxia on excitatory and inhibitory postsynaptic currents显示文摘Khazipov R Congar P Ben-Ari Y 1995J Neu- rophysiol1995,74,5:1
3Pennanent reduction of seizure threshold in postischemic CA3 pyramidal neurons显示文摘Congar P Gaiarsa J PopoVici T 2007Neurophysiol2007,83,4:1
4Permanent reduction of seizure threshold in post-ischemic CA3 pyramidal neurons显示文摘Congar P Gaigrsa J Popovici T 2000Neurophysiol2000,83,4:1
5Pennanent reduction of seizure threshold in postischemic CA3 pyramidal neurons显示文摘Congar P Gaiarsa J PopoVici T 2007Neurophysiol2007,83,:1
6Permanent reduction of seizure threshold in post-ischemic CA3 pvramidal neurons 显示文摘Congar P Gaiarsa J Popovici T 2000J Neurophysiol2000,83,:1
7Pennanent reduction ofse izure threshold in postischem ic CA3 pyramidal neurons 显示文摘Congar P Gaiarsa J Popo Vici T 2007Neu rophysio2007,83,:1
8Differential regulation of metabotropic glutamate receptor- and AMPA receptor-mediated dendritic Ca^2+ signals by presynaptic and postsynaptic activity in hippocampal interneurons显示文摘Topolnik L Congar P Lacaille J C 2005J Neurosci2005,25,:1
9Permanent reduction of seizure threshold in post-isehemic CA3 pyramidal neurons显示文摘Congar P Gaiarsa JL Popoviei T 2000J Neurophysiol2000,83,4:1
10Permanent reduction of seizure threshold in post-ischemic CA3 pyramidal neurorls显示文摘Congar P Gaiarsa J Popovici T 0,,04:1
11Endothelin increases the proliferation of rat olfactory mucosa cells显示文摘The olfactory mucosa holds olfactory sensory neurons directly in contact with an aggressive environment. In order to maintain its integrity, it is one of the few neural zones which are continuously renewed during the whole animal life. Among several factors regulating this renewal, endothelin acts as an anti-apoptotic factor in the rat olfactory epithelium. In the present study, we explored whether endothelin could also act as a proliferative factor. Using primary culture of the olfactory mucosa, we found that an early treatment with endothelin increased its growth. Consistently, a treatment with a mixture of BQ123 and BQ788(endothelin receptor antagonists) decreased the primary culture growth without affecting the cellular death level. We then used combined approaches of calcium imaging, reverse transcriptase-quantitative polymerase chain reaction and protein level measurements to show that endothelin was locally synthetized by the primary culture until it reached confluency. Furthermore, in vivo intranasal instillation of endothelin receptor antagonists led to a decrease of olfactory mucosa cell expressing proliferating cell nuclear antigen(PCNA), a marker of proliferation. Only short-term treatment reduced the PCNA level in the olfactory mucosa cells. When the treatment was prolonged, the PCNA level was not statistically affected but the expression level of endothelin was increased. Overall, our results show that endothelin plays a proliferative role in the olfactory mucosa and that its level is dynamically regulated. This study was approved by the Comité d’éthique en expérimentation animale COMETHEA(COMETHEA C2 EA-45;protocol approval #12-058) on November 28, 2012.Bertrand Bryche Audrey Saint-Albin Claire Le Poupon Schlegel Christine Baly Patrice Congar Nicolas Meunier 2020Neural Regeneration Research2020,15,2:0
12Prada Transformer显示文摘在2009年4月下旬,令人期待已久的Prada Transformer在首尔隆重面世,一系列震撼性的跨文化展览、电影放映和现场活动在这里进行。五个月以来,多项跨学科的项目在这个姿态多变的场地上举行了,为韩国带来别树一帜的视觉艺术大融和。Hyoeun Kim Ye Rin Kang Vincent Mc Ilduff David Moon Mariano Sagasta Claudia Romao Eva Dietrich Alex de Jong Wayne Congar Miguel Huelga de la Fuente Gustavo Paternina-Soberon Nam Joo Kim 2014城市环境设计2014,,6:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费