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| 1 | Mouse embryos cloned from brain tumors显示文摘Cancer cells escape from growth cont rol by accumulating genetic and epig enetic alterations.In rare instances,epigenetic changes alone are oncogenic.Furthermore,a gents that modify DNA methylation or chromatin structure can restore a normal phenotype to cells harboring oncogenic mutations.How ever,it is unclear to what extent epi genetic reprogramming can reverse o ncogenesis.Using somatic nuclear transfer,we show that medul loblastomas arising in Ptc1+/-mice can direct preimplantation develop ment.Additionally,blastocysts derived from medullobl astoma nuclei form postimplantatio n embryos with typical cell layers.T hus,tumor cells can be epigenetically reprogrammed into n ormal cell types.This approach coul d lead to a general strategy for assessing genetic and epigenetic contributions to tumorigenesis. | Li L Connelly MC Wetmore C Curran T Morgan JI | 2003 | 癌症2003，22，7： | 11 |
| 2 | The role of bisphenol A in shaping the brain, epigenome and behav- ior显示文摘 | Wolstenholme J T Rissman E F Connelly J J | 2011 | Horm Behav2011，59，3： | 1 |
| 3 | Dynamic Compression Regulates the Expression and Synthesis of Chondrocyte Specific Matrix Molecules in Bone Marrow Stromal Cells 显示文摘 | Mouw J K Connelly J T Wilson C G | 2007 | Stem Cells2007，25，3： | 1 |
| 4 | The role of bisphenol A in shaping the brain, epigenome and behavior 显示文摘 | WOLSTENHOLME J T RISSMAN E F CONNELLY J J | 2011 | Hormones and Behav- ior2011，59，3： | 1 |
| 5 | Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression显示文摘 | Connelly L Jacobs A T Palacios-Callender M | 2003 | JBiol Chem2003，278，26： | 1 |
| 6 | Early complications of permanent pacemaker implantation:no difference between dual and single chamber systems显示文摘 | Aggarwal R K Connelly D T Ray S G | 1995 | Br Heart J1995，73，： | 1 |
| 7 | The role of Bisphe- nol A in shaping the brain, epigenome and behavior 显示文摘 | Wolstenholme J T Rissman E F Connelly J J | 2011 | Horm Behav2011，59，3： | 1 |
| 8 | An Integrated analog/digital random noise source显示文摘 | W T Holman J A Connelly A B Dowlatabadi | 1997 | IEEE Transactions on Circuits and Systems I Jun1997，44，6： | 1 |
| 9 | Increased nitric oxide levels and iNOS over-expression in oral squamous cell carcinoma显示文摘 | CONNELLY S T MACABEO-ONG M DEKKER N | 2005 | Oral Oncol2005，41，3： | 1 |
| 10 | Evidence for psychrophiles outnumbering psychrotolerant marine bacteria in the springtime coastal Arctic 显示文摘 | Connelly T L Tilburg C M Yager P L | 2006 | Limnology and Oceanography2006，51，2： | 1 |
| 11 | An integrated analog/di-gital random noise source显示文摘 | Holman W T Connelly J A | 1997 | IEEE Trans on Circuits and Systems-I: Fundamental Theory and Applications1997，44，6： | 1 |
| 12 | Transeriptomic and proteomic characterization of the fur modulon in the metal-reducing bacterium Shewanella oneidensis 显示文摘 | WAN X F VERBERKMOES N C MCCUE L A STANEK D CONNELLY H HAUSER L J WU L Y LIU X D YAN T F LEAPHART A HETTICH R L ZHOU J Z THOMPSON D K | 2004 | Journal of Bacteriology2004，186，24： | 1 |
| 13 | Dynamic compression regulates the expression and synthesis of chondrocyte-specific matrix molecules in bone marrow stromal cells显示文摘 | MOUW J K CONNELLY J T WILSON C G | 2007 | Stem Cells2007，25，3： | 1 |
| 14 | Age and Reading:The impact of distraction 显示文摘 | Connelly S Hasher L Zacks T | 1991 | Psychology and Aging1991，，6： | 1 |
| 15 | An optimized wild bootstrap method for evaluation of measurement uncertainties of DTI - derived parameters in human brain 显示文摘 | Zhu T Liu X Connelly PR | 2008 | Neuroimage2008，40，3： | 1 |
| 16 | A molecular fingerprint for medulloblastoma显示文摘Medulloblastoma is the most common malignant pediatric brain tumor. In mice, Ptcl haploinsufficiency and disruption of DNA repair (DNA ligase IV inactivation) or cell cycle regulation (Kipl, Ink4d, or Inkd.c inactivation), in conjunction with p53 dysfunction, predispose to medulloblastoma. To identify genes important for this tumor, we evaluated gene expression profiles in medulloblastomas from these mice. Unexpectedly, medulloblastoma | Lee Y Miller HL Jensen P Hernan R Connelly M Wetmore C Zindy F Roussel MF Curran T Gilbertson RJ McKinnon PJ | 2003 | 中国神经肿瘤杂志2003，1，3： | 1 |
| 17 | Circulating melanoma cells and survival in metastatic melanoma显示文摘 | Rao C Bui T Connelly M | 2011 | International journal of on- cology2011，38，： | 1 |
| 18 | Signaling Theory: A Review and Assessment 显示文摘 | CONNELLY B L CERTO S T IRELAND R D | 2011 | Journal of Management2011，37，1： | 1 |
| 19 | The role of Bis- phenol A in shaping the brain, epigenome and behavior 显示文摘 | Wolstenholme J T Rissman E F Connelly J J | 2011 | Holm Behav2011，59，3： | 1 |
| 20 | Language fMRI abnormalities associated with FOXP2 gene mutation 显示文摘 | Liegeois F Baldeweg T Connelly A | 2003 | Nat Neurosci2003，6，11： | 1 |
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