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| 1 | Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation:Inferences on process modelling requirements and process sensitivities 显示文摘 | Rohit Ramachandran Jonathan MH Poon Constantijn FW Sanders | 2008 | Powder Technology2008,188,2: | 1 |
| 2 | Word skipping in reading: On the interplay of linguistic and visual factors显示文摘 | Denis Drieghe Marc Brysbaert Timothy Desmet Constantijn De Baecke | 2004 | 2004 (1-2)2004,,1: | 1 |
| 3 | Model Predictive Control of Continuous Drum Granulation 显示文摘 | Thomas G Constantijn F W S Wang F Y | 2009 | Journal of Process Control2009,19,4: | 1 |
| 4 | Fluid status,blood pressure,and cardiovascular abnormalities in patients on peritoneal dialysis显示文摘 | Constantijn J Konings A M Frank M | 2002 | Perit Dial Int2002,22,4: | 1 |
| 5 | Potential benefit of lymph node dissection during radical nephrectomy for kidney cancer:A review and critical analysis of current literature显示文摘Objective:The role of lymph node dissection(LND)is still controversial in patients with renal cell carcinoma undergoing surgery.We aimed to provide a comprehensive review of the literature about the effect of LND on survival,prognosis,surgical outcomes,as well as patient selection and available LND templates.Methods:Recent literature(from January 2011 to December 2021)was assessed through PubMed and MEDLINE databases.A narrative review of most relevant articles was provided.Results:The frequencies in which LNDs are being carried out are decreasing due to an increase in minimally invasive and nephron sparing surgery.Moreover,randomized clinical trials and meta-analyses failed to show any survival advantage of LND versus no LND.However,retrospective studies suggest a survival benefit of LND in high-risk patients(bulky tumors,T3-4 stage,and cN1 patients).Moreover,extended LND might provide important staging information,which could be of interest for adjuvant treatment planning.Conclusion:No level 1 evidence of any survival advantage deriving from LND is currently available in literature.Thus,the role of LND is limited to staging purposes.However,low grade evidence suggests a possible role of LND in high-risk patients.Randomized clinical trials are warranted to corroborate these findings. | Michele Marchioni Daniele Amparore Igino Andrea Magli Riccardo Bertolo Umberto Carbonara Selcuk Erdem Alexandre Ingels Constantijn H.J.Muselaers Onder Kara Marco Mascitti Tobias Klatte Maximilian Kriegmair Nicola Pavan Eduard Roussel Angela Pecoraro Laura Marandino Riccardo Campi Luigi Schips | 2022 | Asian Journal of Urology2022,9,3: | 1 |
| 6 | A mechanistic rationale for combining ale- mtuzumab and rituximab in the treatment of ALL 显示文摘 | BART A N MARIANKE L J CONSTANTIJN J M H | 2010 | Blood2010,116,: | 1 |
| 7 | Arterial wall properties in patients with renal failure显示文摘 | Constantijn J A M K Ruben Dammers PL | 2002 | Am J Kidney Dis2002,39,6: | 1 |
| 8 | Current strategies to diagnose and manage positive surgical margins and local recurrence after partial nephrectomy显示文摘Objective:No standard strategy for diagnosis and management of positive surgical margin(PSM)and local recurrence after partial nephrectomy(PN)are reported in literature.This review aims to provide an overview of the current strategies and further perspectives on this patient setting.Methods:A non-systematic review of the literature was completed.The research included the most updated articles(about the last 10 years).Results:Techniques for diagnosing PSMs during PN include intraoperative frozen section,imprinting cytology,and other specific tools.No clear evidence is reported about these methods.Regarding PSM management,active surveillance with a combination of imaging and laboratory evaluation is the first option line followed by surgery.Regarding local recurrence management,surgery is the primary curative approach when possible but it may be technically difficult due to anatomy resultant from previous PN.In this scenario,thermal ablation(TA)may have the potential to circumvent these limitations representing a less invasive alternative.Salvage surgery represents a valid option;six studies analyzed the outcomes of nephrectomy on local recurrence after PN with three of these focused on robotic approach.Overall,complication rates of salvage surgery are higher compared to TA but ablation presents a higher recurrence rate up to 25%of cases that can often be managed with repeat ablation.Conclusion:Controversy still exists surrounding the best strategy for management and diagnosis of patients with PSMs or local recurrence after PN.Active surveillance is likely to be the optimal first-line management option for most patients with PSMs.Ablation and salvage surgery both represent valid options in patients with local recurrence after PN.Conversely,salvage PN and radical nephrectomy have fewer recurrences but are associated with a higher complication rate compared to TA.In this scenario,robotic surgery plays an important role in improving salvage PN and radical nephrectomy outcomes. | Umberto Carbonara Daniele Amparore Cosimo Gentile Riccardo Bertolo Selcuk Erdem Alexandre Ingels Michele Marchioni Constantijn H.J.Muselaers Onder Kara Laura Marandino Nicola Pavan Eduard Roussel Angela Pecoraro Fabio Crocerossa Giuseppe Torre Riccardo Campi Pasquale Ditonno | 2022 | Asian Journal of Urology2022,9,3: | 0 |
| 9 | 未经治疗的血管瘤:生长模式及残余病灶显示文摘背景与目的婴幼儿血管瘤具有快速增长及可能损毁容貌的特性,因此,应给予重视。本研究旨在探讨血管瘤的生长模式和残余病灶的危险因素。方法对1985—2000年间临床监护、未经任何治疗的血管瘤患儿进行随访调查研究。从病案资料中提取相关信息。访问患儿(或其家长)完成问卷调查表,请患儿到我们的门诊,对问卷调查表的相关内容进行讨论,并对患儿行体格检查。对血管瘤的各生长阶段情况进行记录,创建各生长阶段时问轴,如果有残余病灶,对其进行评估。结果共对97例患儿的137处血管瘤病灶进行评估。48%患儿有前期病变。8个月时瘤体尺寸达到最大。消退期平均在患儿2岁时开始,并于平均4岁时结束。69%患儿有残余病灶。表浅结节状血管瘤的残余病灶(74%)明显比深层血管瘤(25%)多(P〈0.001;优势率8.4;95%可信区间2.4~29.1)。97%患儿出现因感染、溃疡、出血未经治疗而产生的瘢痕。结论血管瘤残余病灶会引起表皮损伤。血管瘤的生长模式与形成残余病灶的危险因素问无关联。这一结论将有助于更详细地预知血管瘤的预后情况,并将有助于判别哪些患儿需要治疗,哪些不需要。 | Constantijn G. Bauland Thomas H. Luning Jeroen M. Smit Clark J. Zeebregts Paul H. M. Spauwen 魏峰 高景恒 袁继龙 石杰 张晨 | 2012 | 中国美容整形外科杂志2012,23,3: | 0 |