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		题名	作者	年代	出处	被引量
	1	Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise.	Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook	2011	World Journal of Gastroenterology2011，17，11：	3
	2	Proximal colonic propagating pressure waves sequences and their relationship with movements of content in the proximal human colon显示文摘	Dinning PG Szczesniak MM Cook IJ		0，，05：	1
	3	A matrix for new i- deas in pulmonary fibrosis 显示文摘	Cook DIN Brass DM Schwartz DA	2002	Am J Respir Cell Mol Biol2002，27，2：	1
	4	Proximal colonic propagating pressure waves sequences and their relationship with movements of content in the proximal human colon显示文摘	Dinning P G Szczesniak M M Cook I J	2008	Neurogastroenterology and Motility2008，20，5：	1
	5	排粪梗阻患者近端结肠对直肠机械性和化学性刺激的传动反应受损	Dinning P.G. Bampton P.A. Kennedy M.L. I.J. Cook 尹勇	2006	世界核心医学期刊文摘(胃肠病学分册)2006，0，1：	0
	6	以异常结肠动力模式解释排便梗阻患者的便秘	Dinning P.G. Bampton P.A. Andre J. I.J. Cook 赵天智	2005	世界核心医学期刊文摘(胃肠病学分册)2005，0，1：	0

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