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| 1 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 2 | Gizard formation and the role of Bapxl显示文摘 | Corinne N Lewis C M Jay C C | 2001 | Develop Biol2001，231，1： | 1 |
| 3 | Linking Models of Land Use, Resources, and Economy to Simulate the Development of Mountain Regions (ALPSCAPE)显示文摘 | Corinne Lundstr?m Susanne Kytzia Ariane Walz Adrienne Gret-Regamey Peter Bebi | 2007 | Environmental Management2007，，3： | 1 |
| 4 | Hepatic Lesions Observed in Hepatitis C Virus Transgenic Mice Infected by H elicobacter hepaticus显示文摘 | Emilie Roux‐Goglin Pierre Dubus Corinne Asencio Marthe‐Aline Jutand Jean Rosenbaum Francis Mégraud | 2012 | Helicobacter2012，，1： | 1 |
| 5 | Human immature dendritic cells efficiently bind and take up secretory IgA without the induction of maturation显示文摘 | Corinne Moulon Andrea M Woltman | 2002 | J of Immunology2002，168，： | 1 |
| 6 | Inhibition of cytochrome P450 2El by propofol in human and procine liver microsomes 显示文摘 | CORINNE L ALAIN F YANNICK M | 2002 | Biochem Pharmacol2002，780，： | 1 |
| 7 | Resistance of Streptococcus pneumoniae to defonnylase inhibitor is due to mutations in detB显示文摘 | Peter M Corinne H Joaquim T | 2001 | Antimicrob Agents Chemother2001，45，9： | 1 |
| 8 | Activation of the signal transducers and activators of transcription signaling pathway by Growth Hormone (GH) in skin fibroblasts from normal and GH binding protein-positive laron syndrome children显示文摘 | James S Freeth Corinne M Silva | 1998 | Edocrinology1998，139，1： | 1 |
| 9 | Social Behavior in Fmrl Knockout Mice Carrying a Human FMR1 Transgene 显示文摘 | CORINNE M SPENCER DEANNA F | 2008 | Behavioral Neumseience2008，122，3： | 1 |
| 10 | Gamma radiation effect on vascular smooth muscle cells in culture显示文摘 | Corinne M Gajdusek Hua Tian BS | 1996 | Int J Radiat Oncol Biol Phys1996，36，4： | 1 |
| 11 | Characterization of the active part of the human transferrin gene enhancer and purification of two liver nuclear factors interacting with the TGqTIE, C motif present in this region显示文摘 | PETROPOULOS I CORINNE A G ZAKIN M M | 1991 | J Biological Chemistry1991，266，24： | 1 |
| 12 | Expression of CD21 is developmentally regulated during thymus maturation of human T lymphocytes 显示文摘 | Elizabeth MF Amal M Francoise M Veronique Fremeaux-Bacchi Corinne K Hannah G | 1999 | Int Immunol1999，11，11： | 1 |
| 13 | Role of autologous CD4+ T cell clones in human B non-Hodgkin's lymphoma aborted activation and G1blockade induced by cell-cell contact 显示文摘 | Thierry B Corinne R | 1999 | Eur J Immunol1999，29，： | 1 |
| 14 | Alkaline extractability of pectic arabinan and galactan and their mobility in sugar beet and potato cell walls显示文摘 | Agata Z Corinne R M Catherine G | 2006 | Carbohydrate Polymers2006，65，2： | 1 |
| 15 | The NIMA method for improved moment estimation from doppler spectra显示文摘 | CORINNE S M ROBERT K G LARRY B C | 2002 | J Atmos& Oceanic Technology2002，19，3： | 1 |
| 16 | A fuzzy logic method for improved moment estimation from Doppler spectra显示文摘 | CORNMAN L B GOODRICH R K CORINNE S M | 1998 | J Atmos&Oceanic Technol1998，15，6： | 1 |
| 17 | Free/Bound Water Absorption in an Epoxy Adhesive显示文摘 | Sylvain P Corinne R M Christine S G | 2005 | Polymer2005，46，10： | 1 |
| 18 | Current prospects for the production of coenzyme Q10 in microbes 显示文摘 | Corinne P C Adam M B Vincent J J M | 2007 | Trends in Biotechnology2007，25，11： | 1 |
| 19 | Gastric intestinal metaplasia development in African American predominant United States population显示文摘BACKGROUND Gastric cancer significantly contributes to cancer mortality globally.Gastric intestinal metaplasia(GIM)is a stage in the Correa cascade and a premalignant lesion of gastric cancer.The natural history of GIM formation and progression over time is not fully understood.Currently,there are no clear guidelines on GIM surveillance or management in the United States.AIM To investigate factors associated with GIM development over time in African American-predominant study population.METHODS This is a retrospective longitudinal study in a single tertiary hospital in Washington DC.We retrieved upper esophagogastroduodenoscopies(EGDs)with gastric biopsies from the pathology department database from January 2015 to December 2020.Patients included in the study had undergone two or more EGDswith gastric biopsy.Patients with no GIM at baseline were followed up until they developed GIM or until the last available EGD.Exclusion criteria consisted of patients age<18,pregnancy,previous diagnosis of gastric cancer,and missing data including pathology results or endoscopy reports.The study population was divided into two groups based on GIM status.Univariate and multivariate Cox regression was used to estimate the hazard induced by patient demographics,EGD findings,and Helicobacter pylori(H.pylori)status on the GIM status.RESULTS Of 2375 patients who had at least 1 EGD with gastric biopsy,579 patients were included in the study.138 patients developed GIM during the study follow-up period of 1087 d on average,compared to 857 d in patients without GIM(P=0.247).The average age of GIM group was 64 years compared to 56 years in the non-GIM group(P<0.001).In the GIM group,adding one year to the age increases the risk for GIM formation by 4%(P<0.001).Over time,African Americans,Hispanic,and other ethnicities/races had an increased risk of GIM compared to Caucasians with a hazard ratio(HR)of 2.12(1.16,3.87),2.79(1.09,7.13),and 3.19(1.5,6.76)respectively.No gender difference was observed between the study populations.Gastritis was associated with an increased risk for GIM development with an HR of 1.62(1.07,2.44).On the other hand,H.pylori infection did not increase the risk for GIM.CONCLUSION An increase in age and non-Caucasian race/ethnicity are associated with an increased risk of GIM formation.The effect of H.pylori on GIM is limited in low prevalence areas. | Akram I Ahmad Arielle Lee Claire Caplan Colin Wikholm Ioannis Pothoulakis Zaynab Almothafer NishthaRaval Samantha Marshall Ankit Mishra Nicole Hodgins In Guk Kang Raymond K Chang Zachary Dailey Arvin Daneshmand Anjani Kapadia Jae Hak Oh Brittney Rodriguez Abhinav Sehgal Matthew Sweeney Christopher B Swisher Daniel F Childers Corinne O'Connor Lynette M Sequeira Won Cho | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，10： | 1 |
| 20 | Spot fires: fuel bed flammability and capability of firebrands to ignite fuel beds显示文摘 | Anne G Corinne L M Mercedes G | 2009 | International Journal of Wildland Fire2009，，18： | 1 |
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