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21篇 您的检索式：作者名="Cornil C"

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	题名	作者	年代	出处	被引量
1	Effect of propylene glycol supplementation around parturition on milk yield,reproduction performance and some hormonal and metabolic characteristics in dairy cows显示文摘	Formigoni A Cornil M C Prandi A		0，，01：	1
2	Progress in hydroformylation and carbonylation显示文摘	BELLER M CORNILS B FROHNING C D	1995	J Mol Catal A:Chem1995，104，1：	1
3	Adenocarcinoma of the urachus显示文摘	Cornil C Reynolds CT Kickham CJE	1967	J Urol1967，98，：	1
4	Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia显示文摘A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongation and many signal transduction pathways.Identification of new and relevant compounds targeting the FGFR3 signaling pathway is of broad importance for the treatment of ACH,and natural plant compounds are prime drug candidate sources.Here,we found that the phenolic compound(-)-epicatechin,isolated from Theobroma cacao,effectively inhibited FGFR3’s downstream signaling pathways.Transcriptomic analysis in an Fgfr3 mouse model showed that ciliary mRNA expression was modified and influenced significantly by the Indian hedgehog and PKA pathways.(-)-Epicatechin is able to rescue mRNA expression impairments that control both the structural organization of the primary cilium and ciliogenesis-related genes.In femurs isolated from a mouse model(Fgfr3^(Y367C/+))of ACH,we showed that(-)-epicatechin eliminated bone growth impairment during 6 days of ex vivo culture.In vivo,we confirmed that daily subcutaneous injections of(-)-epicatechin to Fgfr3^(Y367C/+) mice increased bone elongation and rescued the primary cilium defects observed in chondrocytes.This modification to the primary cilia promoted the typical columnar arrangement of flat proliferative chondrocytes and thus enhanced bone elongation.The results of the present proof-of-principle study support(-)-epicatechin as a potential drug for the treatment of ACH.	Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet	2022	Bone Research2022，10，1：	1
5	Carcinoma of the urachus显示文摘	Cornil C	1967	J Urol1967，98，1：	1
6	Lower olefins via Fischer-Tropsch 显示文摘	BUSSEMIER B FROHNING C D CORNILS B	1976	Hydrocarbon Process1976，55，11：	1
7	Lower Olefins via Fischer-Yropsch 显示文摘	Bussemeier B Frohning C D Cornils B	1976	Hydrocarbon Process1976，55，11：	1
8	Effect of propylene glycol supplementation around parturition on milk yield,reproduction performance and some hormonal and metabolic characteristics in dairy cows显示文摘	FORMIGONI A CORNIL M C PRANDI A	1996	J Dairy Res1996，63，1：	1
9	Diversity of mechanisms involved in aromatase regulation and estrogen ac- tion in the brain 显示文摘	CHARLIER T D CORNIL C A BALL G F	2010	Bioehim Biophys Aeta2010，1800，10：	1
10	Lower olefins via Fischer-Tropsch显示文摘	BUSSEMEIER B FROHNING C D CORNIL B	1976	Hydro Proc1976，55，11：	1
11	Dopamine binds to alpha (2)-adrenergic receptors in the song control system of zebra finches (Taeniopygia guttata)显示文摘	CORNIL C A CASTELINO C B BALL G F	2008	Journal of Chemical Neuroanatomy2008，35，2：	1
12	Immunocytochemical localization of ionotropic glutamate receptors subunits in the adult quail forebrain显示文摘	Cornil C Foidart A Minet A	2000	J Comp Neurol2000，428，4：	1
13	Cooperative exosite- dependent cleavage of synaptobrevin by tetanus toxin light chain 显示文摘	Cornille F Martin L Lenoir C	1997	J Biol Chem1997，272，：	1
14	Progress in hydroformylation and carbonylation 显示文摘	BELLER M CORNILS B FROHNING C D	1995	J Mol Catal A: Chem1995，104，1：	1
15	Interplay among catecholamine systems:dopamine binds to alpha2-adrenergic receptors in birds and mammals显示文摘	Cornil C A Ball G F	2008	J Comp Neurol2008，511，61：	1
16	Rapid decreases in preoptic aromatase activity and brain monoanfine concentrations after engaging in male sexual behavior显示文摘	Cornil CA Dalla C Papadopoulou-Daifoti Z	2005	Endocrinology2005，146，9：	1
17	查看详情显示文摘	Martinelli N G Savini M Muccioli L Olivier Y Castet F Zannoni C Beljonne D Cornil J		0，，：	1
18	Chromothripsis from DNA damage in micronuclei显示文摘	Zhang C Z Spektor A Cornils H	2015	Nature2015，522，7555：	1
19	Progress in hydroformylation and carbonylation显示文摘	Cornils B Beller M Frohning C D	1995	Journal of Molecular Catalysis A:Chemical1995，104，：	1
20	Carcinoma of the urachus显示文摘	Cornil C Reynolds CT Kickham CJ		0，，01：	1

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